Search Results - "Yay Donderici, Elifnur"
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Future expenditure risk of silent members: a statistical analysis
Published in BMC health services research (29-07-2016)“…Silent-members are members of a medical health plan who submit no claims for healthcare services in a benefit year despite 12 months of continuous-enrollment…”
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Associations Among Optimal Lung Cancer Treatment, Clinical Outcomes, and Health Care Utilization in Patients Who Underwent Comprehensive Genomic Profiling
Published in Journal of the National Comprehensive Cancer Network (01-01-2024)“…Although immune checkpoint inhibitor immunotherapies are contraindicated as first-line treatment of advanced non-small cell lung cancer (NSCLC) in patients…”
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Population health outcomes of blood-based screening for colorectal cancer in comparison to current screening modalities: insights from a discrete-event simulation model incorporating longitudinal adherence
Published in Journal of medical economics (31-12-2024)“…Insufficient adherence to colorectal cancer (CRC) screening impedes individual and population health benefits, with about one-third of individuals non-adherent…”
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AI-generated synthetic clinical-genomic data for precision oncology research: Validation using a case study on lung adenocarcinoma
Published in Journal of clinical oncology (01-06-2024)“…e13627 Background: The analysis of genomic variants is crucial in precision oncology research, offering insights into cancer risks and progression, especially…”
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ctDNA-based genomic landscape analysis to evaluate molecular brake and gatekeeper mutations in FGFR2 alterations
Published in Journal of clinical oncology (01-06-2023)“…3049 Background: FGFR2 and FGFR3 (FGFR2/3) gene alterations are oncogenic drivers found across various cancer types and have been successful targets of drug…”
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Circulating tumor DNA molecular analyses and real-world evidence outcomes of FGFR2 amplified gastroesophageal cancers
Published in The oncologist (Dayton, Ohio) (05-08-2024)“…In addition to the existing biomarkers HER2 and PD-L1, FGFR2b has become an area of interest for the development of new targeted-based treatment. Given that…”
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Impact of STK11 mutation on first-line immune checkpoint inhibitor (ICI) outcomes in a real-world KRAS G12C mutant lung adenocarcinoma cohort
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 9106 Background: The introduction of KRAS G12C inhibitors into clinical trials has demonstrated promise and may provide a new therapeutic option…”
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Abstract 4122: Occurrence of BRAF class II and III alterations is common across solid tumors and is associated with inferior clinical outcomes in NSCLC and melanoma
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Background: Oncogenic BRAF alterations can be categorized by their distinct structural and signaling properties which lead to activation of the MAPK…”
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