Search Results - "Yau, Christina"

Rethinking the Standard for Ductal Carcinoma In Situ Treatment by Esserman, Laura, Yau, Christina

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Pathologic Complete Response Predicts Recurrence-Free Survival More Effectively by Cancer Subset: Results From the I-SPY 1 TRIAL—CALGB 150007/150012, ACRIN 6657 by ESSERMAN, Laura J, BERRY, Donald A, LIVASY, Chad, KRONTIRAS, Helen, MONTGOMERY, Leslie, TRIPATHY, Debasish, LEHMAN, Constance, LIU, Minetta C, OLOPADE, Olufunmilayo I, RUGO, Hope S, CARPENTER, John T, DRESSLER, Lynn, DEMICHELE, Angela, CHHIENG, David, SINGH, Baljit, MIES, Carolyn, RABBAN, Joseph, CHEN, Yunn-Yi, GIRI, Dilip, VAN'T VEER, Laura, HYLTON, Nola, CAREY, Lisa, DAVIS, Sarah E, BUXTON, Meredith, HUDIS, Cliff, GRAY, Joe W, PEROU, Charles, YAU, Christina

“…Neoadjuvant chemotherapy for breast cancer provides critical information about tumor response; how best to leverage this for predicting recurrence-free…”
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Event-Related Desynchronization During Mirror Visual Feedback: A Comparison of Older Adults and People After Stroke by Fong, Kenneth N. K., Ting, K. H., Zhang, Jack J. Q., Yau, Christina S. F., Li, Leonard S. W.

“…Event-related desynchronization (ERD), as a proxy for mirror neuron activity, has been used as a neurophysiological marker for motor execution after mirror…”
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Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer by Lee, Joyce V., Housley, Filomena, Yau, Christina, Nakagawa, Rachel, Winkler, Juliane, Anttila, Johanna M., Munne, Pauliina M., Savelius, Mariel, Houlahan, Kathleen E., Van de Mark, Daniel, Hemmati, Golzar, Hernandez, Grace A., Zhang, Yibing, Samson, Susan, Baas, Carole, Kok, Marleen, Esserman, Laura J., van ‘t Veer, Laura J., Rugo, Hope S., Curtis, Christina, Klefström, Juha, Matloubian, Mehrdad, Goga, Andrei

“…Few patients with triple negative breast cancer (TNBC) benefit from immune checkpoint inhibitors with complete and durable remissions being quite rare…”
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A Randomized Controlled Trial of Mental Imagery Augment Generalization of Learning in Acute Poststroke Patients by LIU, Karen P. Y, CHAN, Chetwyn C. H, WONG, Rebecca S. M, KWAN, Ivan W. L, YAU, Christina S. F, LI, Leonard S. W, LEE, Tatia M. C

“…Our previous studies demonstrated that mental imagery intervention enhanced poststroke patients relearning daily task performance. This study aimed to test the…”
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Gene co-expression modules as clinically relevant hallmarks of breast cancer diversity by Wolf, Denise M, Lenburg, Marc E, Yau, Christina, Boudreau, Aaron, van 't Veer, Laura J

“…Co-expression modules are groups of genes with highly correlated expression patterns. In cancer, differences in module activity potentially represent the…”
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A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer by Yau, Christina, Esserman, Laura, Moore, Dan H, Waldman, Fred, Sninsky, John, Benz, Christopher C

“…Various multigene predictors of breast cancer clinical outcome have been commercialized, but proved to be prognostic only for hormone receptor (HR) subsets…”
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Application of virtual reality for peritoneal dialysis exchange learning in patients with end-stage renal disease and cognitive impairment by Lee, Connie M. S., Fong, Kenneth N. K., Mok, Maggie M. Y., Lam, M. K., Kung, Y., Chan, Paven P. W., Ma, Maggie K. M., Lui, S. L., Kwan, Lorraine P. Y., Chu, W. L., Hui, P. C., Yau, Christina S. F., Kwan, Ivan W. L., Chan, Kelsey Y. M., Chan, T. M.

“…Cognitive impairment is not uncommon in patients with end-stage renal disease and can make it more difficult for these patients to carry out peritoneal…”
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The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting by Severson, Tesa M, Wolf, Denise M, Yau, Christina, Peeters, Justine, Wehkam, Diederik, Schouten, Philip C, Chin, Suet-Feung, Majewski, Ian J, Michaut, Magali, Bosma, Astrid, Pereira, Bernard, Bismeijer, Tycho, Wessels, Lodewyk, Caldas, Carlos, Bernards, René, Simon, Iris M, Glas, Annuska M, Linn, Sabine, van 't Veer, Laura

“…Patients with BRCA1-like tumors correlate with improved response to DNA double-strand break-inducing therapy. A gene expression-based classifier was developed…”
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RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer by Engebraaten, Olav, Yau, Christina, Berg, Kristian, Borgen, Elin, Garred, Øystein, Berstad, Maria E. B., Fremstedal, Ane S. V., DeMichele, Angela, Veer, Laura van ’t, Esserman, Laura, Weyergang, Anette

“…HER2 is a predictive biomarker for HER2-targeted therapeutics. For antibody–drug conjugates (ADCs; e.g., trastuzumab emtansine (T-DM1)), HER2 is utilized as a…”
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The Effect of Mirror Visual Feedback on Spatial Neglect for Patients after Stroke: A Preliminary Randomized Controlled Trial by Fong, Kenneth N K, Ting, K H, Zhang, Xinfei, Yau, Christina S F, Li, Leonard S W

“…We investigated the effects of mirror visual feedback (MVF), with reference to using a glass wall or a covered mirror, on the reduction of spatial neglect for…”
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A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population by Kang, Taekyu, Yau, Christina, Wong, Christopher K, Sanborn, John Z, Newton, Yulia, Vaske, Charlie, Benz, Stephen C, Krings, Gregor, Camarda, Roman, Henry, Jill E, Stuart, Josh, Powell, Mark, Benz, Christopher C

“…Abstract Background Previous studies have identified and validated a risk-associated Active transcriptome phenotype commonly expressed in the cancer-adjacent…”
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B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast cancer by Steenbruggen, Tessa G, Wolf, Denise M, Campbell, Michael J, Sanders, Joyce, Cornelissen, Sten, Thijssen, Bram, Salgado, Roberto A, Yau, Christina, O-Grady, Nick, Basu, Amrita, Bhaskaran, Rajith, Mittempergher, Lorenza, Hirst, Gillian L, Coppe, Jean-Philippe, Kok, Marleen, Sonke, Gabe S, van 't Veer, Laura J, Horlings, Hugo M

“…Abstract Background Despite major improvements in treatment of HER2-positive metastatic breast cancer (MBC), only few patients achieve complete remission and…”
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Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer by Lee, Joyce V., Housley, Filomena, Yau, Christina, Nakagawa, Rachel, Winkler, Juliane, Anttila, Johanna M., Munne, Pauliina M., Savelius, Mariel, Houlahan, Kathleen E., Van de Mark, Daniel, Hemmati, Golzar, Hernandez, Grace A., Zhang, Yibing, Samson, Susan, Baas, Carole, Kok, Marleen, Esserman, Laura J., van ‘t Veer, Laura J., Rugo, Hope S., Curtis, Christina, Klefström, Juha, Matloubian, Mehrdad, Goga, Andrei

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Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes by Yu, Katharine, Basu, Amrita, Yau, Christina, Wolf, Denise M, Goodarzi, Hani, Bandyopadhyay, Sourav, Korkola, James E, Hirst, Gillian L, Asare, Smita, DeMichele, Angela, Hylton, Nola, Yee, Douglas, Esserman, Laura, van 't Veer, Laura, Sirota, Marina

“…Drug resistance is a major obstacle in cancer treatment and can involve a variety of different factors. Identifying effective therapies for drug resistant…”
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Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer by Lips, Esther H., Mukhtar, Rita A., Yau, Christina, de Ronde, Jorma J., Livasy, Chad, Carey, Lisa A., Loo, Claudette E., Vrancken-Peeters, Marie-Jeanne T. F. D., Sonke, Gabe S., Berry, Donald A., van‘t Veer, Laura J., Esserman, Laura J., Wesseling, Jelle, Rodenhuis, Sjoerd, Shelley Hwang, E.

“…Invasive lobular carcinoma (ILC) has been reported to be less responsive to neoadjuvant chemotherapy (NAC) than invasive ductal carcinoma (IDC). We sought to…”
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Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer by Zhou, Yamei, Yau, Christina, Gray, Joe W, Chew, Karen, Dairkee, Shanaz H, Moore, Dan H, Eppenberger, Urs, Eppenberger-Castori, Serenella, Benz, Christopher C

“…Signaling pathways that converge on two different transcription factor complexes, NFkappaB and AP-1, have been identified in estrogen receptor (ER)-positive…”
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Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers by Yau, Christina, Benz, Christopher C

“…Oxidative stress can modify estrogen receptor (ER) structure and function, including induction of progesterone receptor (PR), altering the biology and clinical…”
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Biologic markers determine both the risk and the timing of recurrence in breast cancer by Esserman, Laura J., Moore, Dan H., Tsing, Pamela J., Chu, Philip W., Yau, Christina, Ozanne, Elissa, Chung, Robert E., Tandon, Vickram J., Park, John W., Baehner, Frederick L., Kreps, Stig, Tutt, Andrew N. J., Gillett, Cheryl E., Benz, Christopher C.

“…Breast cancer has a long natural history. Established and emerging biologic markers address overall risk but not necessarily timing of recurrence. 346 adjuvant…”
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Circulating tumor DNA and magnetic resonance imaging to predict neoadjuvant chemotherapy response and recurrence risk by Magbanua, Mark Jesus M., Li, Wen, Wolf, Denise M., Yau, Christina, Hirst, Gillian L., Swigart, Lamorna Brown, Newitt, David C., Gibbs, Jessica, Delson, Amy L., Kalashnikova, Ekaterina, Aleshin, Alexey, Zimmermann, Bernhard, Chien, A. Jo, Tripathy, Debu, Esserman, Laura, Hylton, Nola, van ‘t Veer, Laura

“…We investigated whether serial measurements of circulating tumor DNA (ctDNA) and functional tumor volume (FTV) by magnetic resonance imaging (MRI) can be…”
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