Search Results - "Yatsenko, Andriy S."

Distant activation of Notch signaling induces stem cell niche assembly by Yatsenko, Andriy S, Shcherbata, Halyna R

“…Here we show that multiple modes of Notch signaling activation specify the complexity of spatial cellular interactions necessary for stem cell niche assembly…”
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Drosophila miR-9a Targets the ECM Receptor Dystroglycan to Canalize Myotendinous Junction Formation by Yatsenko, Andriy S., Shcherbata, Halyna R.

“…Establishment of intercellular interactions between various cell types of different origin is vital for organism development and tissue maintenance. Therefore,…”
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Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier by Tsap, Mariana I, Yatsenko, Andriy S, Hegermann, Jan, Beckmann, Bibiana, Tsikas, Dimitrios, Shcherbata, Halyna R

“…Mutations in Swiss cheese (SWS) gene or its vertebrate orthologue neuropathy target esterase (NTE) lead to progressive neuronal degeneration in flies and…”
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Notch signaling sculpts the stem cell niche by Zamfirescu, Ana-Maria, Yatsenko, Andriy S, Shcherbata, Halyna R

“…Adult stem cells depend on their niches for regulatory signaling that controls their maintenance, division, and their progeny differentiation. While…”
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Profiling of the muscle-specific dystroglycan interactome reveals the role of Hippo signaling in muscular dystrophy and age-dependent muscle atrophy by Yatsenko, Andriy S, Kucherenko, Mariya M, Xie, Yuanbin, Aweida, Dina, Urlaub, Henning, Scheibe, Renate J, Cohen, Shenhav, Shcherbata, Halyna R

“…Dystroglycanopathies are a group of inherited disorders characterized by vast clinical and genetic heterogeneity and caused by abnormal functioning of the ECM…”
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Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization by Yatsenko, Andriy S, Kucherenko, Mariya M, Xie, Yuanbin, Urlaub, Henning, Shcherbata, Halyna R

“…To assemble a brain, differentiating neurons must make proper connections and establish specialized brain compartments. Abnormal levels of cell adhesion…”
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Loss of swiss cheese in Neurons Contributes to Neurodegeneration with Mitochondria Abnormalities, Reactive Oxygen Species Acceleration and Accumulation of Lipid Droplets in Drosophila Brain by Melentev, Pavel A., Ryabova, Elena V., Surina, Nina V., Zhmujdina, Darya R., Komissarov, Artem E., Ivanova, Ekaterina A., Boltneva, Natalia P., Makhaeva, Galina F., Sliusarenko, Mariana I., Yatsenko, Andriy S., Mohylyak, Iryna I., Matiytsiv, Nataliya P., Shcherbata, Halyna R., Sarantseva, Svetlana V.

“…Various neurodegenerative disorders are associated with human NTE/PNPLA6 dysfunction. Mechanisms of neuropathogenesis in these diseases are far from clearly…”
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Increase of α-dicarbonyls in liver and receptor for advanced glycation end products on immune cells are linked to nonalcoholic fatty liver disease and liver cancer by Petriv, Nataliia, Neubert, Lavinia, Vatashchuk, Myroslava, Timrott, Kai, Suo, Huizhen, Hochnadel, Inga, Huber, René, Petzold, Christina, Hrushchenko, Anastasiia, Yatsenko, Andriy S., Shcherbata, Halyna R., Wedemeyer, Heiner, Lichtinghagen, Ralf, Falfushynska, Halina, Lushchak, Volodymyr, Manns, Michael P., Bantel, Heike, Semchyshyn, Halyna, Yevsa, Tetyana

“…Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver with a very poor prognosis and constantly growing incidence. Among other…”
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Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy by Shcherbata, Halyna R, Yatsenko, Andriy S, Patterson, Larissa, Sood, Vanita D, Nudel, Uri, Yaffe, David, Baker, David, Ruohola-Baker, Hannele

“…Perturbation in the Dystroglycan (Dg)–Dystrophin (Dys) complex results in muscular dystrophies and brain abnormalities in human. Here we report that Drosophila…”
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Genetic modifier screens reveal new components that interact with the Drosophila dystroglycan-dystrophin complex by Kucherenko, Mariya M, Pantoja, Mario, Yatsenko, Andriy S, Shcherbata, Halyna R, Fischer, Karin A, Maksymiv, Dariya V, Chernyk, Yaroslava I, Ruohola-Baker, Hannele

“…The Dystroglycan-Dystrophin (Dg-Dys) complex has a capacity to transmit information from the extracellular matrix to the cytoskeleton inside the cell. It is…”
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Stereotypical architecture of the stem cell niche is spatiotemporally established by miR-125-dependent coordination of Notch and steroid signaling by Yatsenko, Andriy S, Shcherbata, Halyna R

“…Stem cell niches act as signaling platforms that regulate stem cell self-renewal and sustain stem cells throughout life; however, the specific developmental…”
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Ecdysteroids affect Drosophila ovarian stem cell niche formation and early germline differentiation by König, Annekatrin, Yatsenko, Andriy S, Weiss, Miriam, Shcherbata, Halyna R

“…Previously, it has been shown that in Drosophila steroid hormones are required for progression of oogenesis during late stages of egg maturation. Here, we show…”
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Tissue-specific regulation of translational readthrough tunes functions of the traffic jam transcription factor by Karki, Prajwal, Carney, Travis D, Maracci, Cristina, Yatsenko, Andriy S, Shcherbata, Halyna R, Rodnina, Marina V

“…Translational readthrough (TR) occurs when the ribosome decodes a stop codon as a sense codon, resulting in two protein isoforms synthesized from the same…”
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A Putative Src Homology 3 Domain Binding Motif but Not the C-terminal Dystrophin WW Domain Binding Motif Is Required for Dystroglycan Function in Cellular Polarity in Drosophila by Yatsenko, Andriy S., Gray, Elizabeth E., Shcherbata, Halyna R., Patterson, Larissa B., Sood, Vanita D., Kucherenko, Mariya M., Baker, David, Ruohola-Baker, Hannele

“…The conserved dystroglycan-dystrophin (Dg·Dys) complex connects the extracellular matrix to the cytoskeleton. In humans as well as Drosophila, perturbation of…”
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miRNA-based buffering of the cobblestone–lissencephaly-associated extracellular matrix receptor dystroglycan via its alternative 3′-UTR by Yatsenko, Andriy S., Marrone, April K., Shcherbata, Halyna R.

“…Many proteins are expressed dynamically during different stages of cellular life and the accuracy of protein amounts is critical for cell endurance. Therefore,…”
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Measurement of metabolic rate in Drosophila using respirometry by Yatsenko, Andriy S, Marrone, April K, Kucherenko, Mariya M, Shcherbata, Halyna R

“…Metabolic disorders are a frequent problem affecting human health. Therefore, understanding the mechanisms that regulate metabolism is a crucial scientific…”
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Paraffin-Embedded and Frozen Sections of Drosophila Adult Muscles by Kucherenko, Mariya M., Marrone, April K., Rishko, Valentyna M., Yatsenko, Andriy S., Klepzig, Annekatrin, Shcherbata, Halyna R.

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Paraffin-embedded and frozen sections of Drosophila adult muscles by Kucherenko, Mariya M, Marrone, April K, Rishko, Valentyna M, Yatsenko, Andriy S, Klepzig, Annekatrin, Shcherbata, Halyna R

“…The molecular characterization of muscular dystrophies and myopathies in humans has revealed the complexity of muscle disease and genetic analysis of muscle…”
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Ecdysteroids affect Drosophila ovarian stem cell niche formation and early germline differentiation: Steroids in stem cells and their niches by König, Annekatrin, Yatsenko, Andriy S, Weiss, Miriam, Shcherbata, Halyna R

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Measurement of Metabolic Rate in Drosophila using Respirometry by Yatsenko, Andriy S., Marrone, April K., Kucherenko, Mariya M., Shcherbata, Halyna R.

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