Search Results - "Yates, Susan P"

Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry by Merrill, A. Rod, Andersen, Gregers R, Jørgensen, René, Yates, Susan P, Marquez, Victor E, Schwan, Adrian L, Boesen, Thomas

“…The bacteria causing diphtheria, whooping cough, cholera and other diseases secrete mono-ADP-ribosylating toxins that modify intracellular proteins. Here, we…”
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Structural Basis of the Substrate Specificity of Bifunctional Isocitrate Dehydrogenase Kinase/Phosphatase by Yates, Susan P, Edwards, Thomas E, Bryan, Cassie M, Stein, Adam J, Van Voorhis, Wesley C, Myler, Peter J, Stewart, Lance J, Zheng, Jimin, Jia, Zongchao

“…Isocitrate dehydrogenase kinase/phosphatase (AceK) regulates entry into the glyoxylate bypass by reversibly phosphorylating isocitrate dehydrogenase (ICDH). On…”
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Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa by Yates, Susan P, Taylor, Patricia L, Jørgensen, René, Ferraris, Dana, Zhang, Jie, Andersen, Gregers R, Merrill, A Rod

“…The mono-ADPRT (mono-ADP-ribosyltransferase), Pseudomonas aeruginosa ETA (exotoxin A), catalyses the transfer of ADP-ribose from NAD+ to its protein substrate…”
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Structural and mechanistic insights into the bifunctional enzyme isocitrate dehydrogenase kinase/phosphatase AceK by Zheng, Jimin, Yates, Susan P., Jia, Zongchao

“…The switch between the Krebs cycle and the glyoxylate bypass is controlled by isocitrate dehydrogenase kinase/phosphatase (AceK). AceK, a bifunctional enzyme,…”
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Crystal Structure of ADP-ribosylated Ribosomal Translocase from Saccharomyces cerevisiae by Jørgensen, René, Yates, Susan P., Teal, David J., Nilsson, Jakob, Prentice, Gerry A., Merrill, A. Rod, Andersen, Gregers Rom

“…The crystal structure of ADP-ribosylated yeast elongation factor 2 in the presence of sordarin and GDP has been determined at 2.6 Å resolution. The…”
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Stealth and mimicry by deadly bacterial toxins by Yates, Susan P., Jørgensen, René, Andersen, Gregers R., Merrill, A. Rod

“…Diphtheria toxin and exotoxin A are well-characterized members of the ADP-ribosyltransferase toxin family that function as virulence factors in the pathogenic…”
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Overexpression of cardiac actin with baculovirus is promoter dependent by Yates, Susan P., Otley, Marissa D., Dawson, John F.

“…The influence of the promoter and an N-terminal hexahistidine tag on human cardiac actin (ACTC) expression and function was investigated using four baculovirus…”
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Actin polymerization is controlled by residue size at position 204 by Yates, Susan P, Loncar, Ana, Dawson, John F

“…Previous work has shown that purified double mutant A204C/C374A yeast actin is polymerization-deficient in vitro under physiological concentrations. To…”
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Characterization of oxidized nicotinamide adenine dinucleotide (NAD +) analogues using a high-pressure-liquid-chromatography-based NAD +-glycohydrolase assay and comparison with fluorescence-based measurements by Yates, Susan P., Merrill, A. Rod

“…A high-pressure-liquid-chromatography (HPLC)-based technique was developed to assess the oxidized nicotinamide adenine dinucleotide (NAD +)-glycohydrolase…”
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Elucidation of eukaryotic elongation factor-2 contact sites within the catalytic domain of Pseudomonas aeruginosa exotoxin A by Yates, Susan P, Merrill, Allan R

“…Pseudomonas aeruginosa produces the virulence factor, ETA (exotoxin A), which catalyses an ADP-ribosyltransferase reaction of its target protein, eEF2…”
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Insight into the catalytic mechanism of Pseudomonas aeruginosa exotoxin A. Studies of toxin interaction with eukaryotic elongation factor-2 by Armstrong, Souzan, Yates, Susan P, Merrill, A Rod

“…The molecular nature of the protein-protein interactions between the catalytic domain from Pseudomonas aeruginosa exotoxin A (PE24H) and its protein substrate,…”
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A Catalytic Loop within Pseudomonas aeruginosa Exotoxin A Modulates Its Transferase Activity by Yates, Susan P., Merrill, A.Rod

“…Mutagenesis techniques were used to replace two loop regions within the catalytic domain of Pseudomonas aeruginosa exotoxin A (ETA) with functionally silent…”
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Insight into the Catalytic Mechanism of Pseudomonas aeruginosa Exotoxin A by Armstrong, Souzan, Yates, Susan P., Merrill, A. Rod

“…The molecular nature of the protein-protein interactions between the catalytic domain from Pseudomonas aeruginosa exotoxin A (PE24H) and its protein substrate,…”
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