Search Results - "Yates, Mark T."

Antioxidant activity of probucol and its analogs in hypercholesterolemic Watanabe rabbits by Mao, Simon J. T, Yates, Mark T, Rechtin, Ann E, Jackson, Richard L, Van Sickle, William A

“…Probucol (1) and probucol analogues with the substitutions at the disulfide-linked carbon (2, 3) and an additional substitution at a tert-butyl of each…”
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After Pell Grants: The Neoliberal Assault on Prisoners by Yates, Mark T., Lakes, Richard D.

“…The number of prisoners in the United States has accelerated over the past thirty years, giving it the highest incarceration rate in the world. The rise in the…”
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Interaction of hirudin with thrombin: identification of a minimal binding domain of hirudin that inhibits clotting activity by Mao, Simon J. T, Yates, Mark T, Owen, Thomas J, Krstenansky, John L

“…Hirudin, isolated from the European leech Hirudo medicinalis, is a potent inhibitor of thrombin, forming an almost irreversible thrombin-hirudin complex…”
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Antioxidant activity and serum levels of probucol and probucal metabolites by Mao, S J, Yates, M T, Jackson, R L

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Positional effects of sulfation in hirudin and hirudin PA related anticoagulant peptides by Payne, Marguerite H, Krstenansky, John L, Yates, Mark T, Mao, Simon J. T

“…C-Terminal fragment analogues of the leech protein hirudin or the related protein hirudin PA block thrombin's cleavage of fibrinogen. Three series of synthetic…”
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N-Terminal requirements of small peptide anticoagulants based on hirudin 54-65 by Owen, Thomas J, Krstenansky, John L, Yates, Mark T, Mao, Simon J. T

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Congressional Debates over Prisoner Education: A Critical Discourse Analysis by Yates, Mark T

“…The United States has the highest incarceration rate of any country. The causes for the large number of prisoners can be traced, in part, to a politicized war…”
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Human hepatic triglyceride lipase expression reduces high density lipoprotein and aortic cholesterol in cholesterol-fed transgenic mice by BUSCH, S. J, BARNHART, R. L, MARTIN, G. A, FITZGERALD, M. C, YATES, M. T, MAO, S. J. T, THOMAS, C. E, JACKSON, R. L

“…We have produced a line of transgenic mice expressing human hepatic triglyceride lipase (hH-TGL) to examine the in vivo effects of hepatic lipase expression on…”
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Congressional debates over prisoner education: A critical discourse analysis by Yates, Mark T

“…The United States has the highest incarceration rate of any country. The causes for the large number of prisoners can be traced, in part, to a politicized war…”
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A protective role for nitric oxide in the oxidative modification of low density lipoproteins by mouse macrophages by Yates, Mark T., Lambert, Laurie E., Whitten, Jeffrey P., McDonald, Ian, Mano, Masayuki, Ku, George, Mao, Simon J.T.

“…Low density lipoproteins (LDL) oxidatively modified by macrophages have been shown to be atherogenic in ex vivo studies. We studied the potential role of…”
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Attenuation of atherosclerosis in a modified strain of hypercholesterolemic Watanabe rabbits with use of a probucol analogue (MDL 29,311) that does not lower serum cholesterol by Mao, S J, Yates, M T, Parker, R A, Chi, E M, Jackson, R L

“…Probucol is a drug that lowers plasma cholesterol in both humans and animals. In low density lipoprotein (LDL) receptor-deficient Watanabe rabbits, probucol…”
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Development of MDL 28,050, a small stable antithrombin agent based on a functional domain of the leech protein, hirudin by Krstenansky, J L, Broersma, R J, Owen, T J, Payne, M H, Yates, M T, Mao, S J

“…MDL 28,050 is a decapeptide antithrombin agent that inhibits alpha-thrombin-induced fibrin clot formation by binding to a non-catalytic site on alpha-thrombin…”
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Antioxidant and cholesterol lowering properties of 2,6-DI- t-butyl-4-[(dimethylphenylsilyl)methyloxy]phenol and derivatives: A new class of anti-atherogenic compounds by Parker, Roger A., Barnhart, Roger L., Chen, Kim S., Edwards, Michael L., Matt, James E., Rhinehart, Barry L., Robinson, Keith M., Vaal, Mark J., Yates, Mark T.

“…Di- t-butylphenol derivatives were synthesized and evaluated as antioxidants and cholesterol lowering agents. When evaluated in cholesterol-fed rabbits, the…”
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Anticoagulant peptides. Nature of the interaction of the C-terminal region of hirudin with a noncatalytic binding site on thrombin by Krstenansky, John L., Owen, Thomas J., Yates, Mark T., Mao, Simon J. T.

“…A series of 20 C-terminal fragment analogues of the anticoagulant peptide hirudin were synthesized by solid-phase techniques in order to investigate the nature…”
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The C‐terminal binding domain of hirullin P18 by Krstenansky, John L., Owen, Thomas J., Yates, Mark T., Mao, Simon J.T.

“…Hirullin P18 is a 61‐amino acid hirudin‐related protein having potent antithrombin activity. Similar to hirudin, it contains a highly acidic C‐terminus, but…”
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The C-terminal binding domain of hirullin P18: Antithrombin activity and comparison to hirudin peptides by Krstenansky, John L., Owen, Thomas J., Yates, Mark T., Mao, Simon J.T.

“…Hirullin P18 is a 61-amino acid hirudin-related protein having potent antithrombin activity. Similar to hirudin, it contains a highly acidic C-terminus, but…”
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N-terminal requirements of small peptide anticoagulants based on hirudin54-65 by OWEN, T. J, KRSTENANSKY, J. L, YATES, M. T, MAO, S. J. T

“…C-terminal fragment analogues of the leech anticoagulant peptide hirudin represent a unique class of thrombin inhibitors that blocks thrombin's cleavage of…”
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Comparison of hirudin and hirudin PA C-terminal fragments and related analogs as antithrombin agents by Krstenansky, J L, Owen, T J, Yates, M T, Mao, S J

“…Hirudin PA54-66 and related hirudin fragment analogs were synthesized and assessed for their inhibition of thrombin-induced fibrin-clot formation in plasma…”
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Rapid purification and revised amino-terminal sequence of hirudin: a specific thrombin inhibitor of the bloodsucking leech by Mao, S J, Yates, M T, Blankenship, D T, Cardin, A D, Krstenansky, J L, Lovenberg, W, Jackson, R L

“…Hirudin is a specific polypeptide thrombin inhibitor consisting of 65 amino acids that is produced by the leech, Hirudo medicinalis. We describe a rapid method…”
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Preparation of antibodies to a synthetic C terminus of hirudin and identification of an antigenic site by Mao, S J, Yates, M T, Owen, T J, Krstenansky, J L

“…Hirudin is a 65 amino acid anticoagulant peptide produced in the leech. The single polypeptide is cross-linked by three disulfide linkages in the NH2 terminal…”
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