Search Results - "Yates, Luke"

The Long and Short of MicroRNA by Yates, Luke A., Norbury, Chris J., Gilbert, Robert J.C.

“…MicroRNAs (miRNAs) are versatile regulators of gene expression in higher eukaryotes. In order to silence many different mRNAs in a precise manner, miRNA…”
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Structural basis of homologous recombination by Sun, Yueru, McCorvie, Thomas J., Yates, Luke A., Zhang, Xiaodong

“…Homologous recombination (HR) is a pathway to faithfully repair DNA double-strand breaks (DSBs). At the core of this pathway is a DNA recombinase, which, as a…”
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Interfacial Thermal Conductance across Room-Temperature-Bonded GaN/Diamond Interfaces for GaN-on-Diamond Devices by Cheng, Zhe, Mu, Fengwen, Yates, Luke, Suga, Tadatomo, Graham, Samuel

“…The wide bandgap, high-breakdown electric field, and high carrier mobility makes GaN an ideal material for high-power and high-frequency electronics…”
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Cross validation for model selection: A review with examples from ecology by Yates, Luke A., Aandahl, Zach, Richards, Shane A., Brook, Barry W.

“…Specifying, assessing, and selecting among candidate statistical models is fundamental to ecological research. Commonly used approaches to model selection are…”
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Eating together and eating alone: meal arrangements in British households by Yates, Luke, Warde, Alan

“…Sociology traditionally accounts for eating in terms of the social organization of meals, their provision and consumption. A recurrent public concern is that…”
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Regulation of DNA break repair by RNA by Yates, Luke A.

“…Genomic stability is critical for cell survival and its effective repair when damaged is a vital process for preserving genetic information. Failure to…”
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Phosphoregulation of the checkpoint kinase Mec1ATR by Yates, Luke A., Zhang, Xiaodong

“…Yeast Mec1, and its mammalian ortholog, Ataxia-Telangiectasia and Rad3-related, are giant protein kinases central to replication stress and double strand DNA…”
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Structures and regulations of ATM and ATR, master kinases in genome integrity by Williams, Rhys M, Yates, Luke A, Zhang, Xiaodong

“…•cryo-EM structures of ATMTel1 and ATRMec1 reveal the molecular basis for their intrinsically low kinase activities.•PRD-Insert plays key roles in maintaining…”
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A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA by Yates, Luke A., Aramayo, Ricardo J., Pokhrel, Nilisha, Caldwell, Colleen C., Kaplan, Joshua A., Perera, Rajika L., Spies, Maria, Antony, Edwin, Zhang, Xiaodong

“…Replication Protein A (RPA), the major eukaryotic single stranded DNA-binding protein, binds to exposed ssDNA to protect it from nucleases, participates in a…”
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A DNA damage–induced phosphorylation circuit enhances Mec1ATR Ddc2ATRIP recruitment to Replication Protein A by Yates, Luke A, Tannous, Elias A, Morgan, R Marc, Burgers, Peter M, Zhang, Xiaodong

“…The cell cycle checkpoint kinase Mec1ATR and its integral partner Ddc2ATRIP are vital for the DNA damage and replication stress response. Mec1–Ddc2 "senses"…”
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Parsimonious model selection using information theory: a modified selection rule by Yates, Luke A., Richards, Shane A., Brook, Barry W.

“…Information-theoretic approaches to model selection, such as Akaike’s information criterion (AIC) and cross validation, provide a rigorous framework to select…”
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Cryptic enzymatic assembly of peptides armed with β-lactone warheads by Xu, Guangcai, Torri, Daniele, Cuesta-Hoyos, Sebastian, Panda, Deepanjan, Yates, Luke R. L., Zallot, Rémi, Bian, Kehan, Jia, Dongxu, Iorgu, Andreea I., Levy, Colin, Shepherd, Sarah A., Micklefield, Jason

“…Nature has evolved biosynthetic pathways to molecules possessing reactive warheads that inspired the development of many therapeutic agents, including…”
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Dominant carnivore loss benefits native avian and invasive mammalian scavengers by Fielding, Matthew W, Cunningham, Calum X, Buettel, Jessie C, Stojanovic, Dejan, Yates, Luke A, Jones, Menna E, Brook, Barry W

“…Scavenging by large carnivores is integral for ecosystem functioning by limiting the build-up of carrion and facilitating widespread energy flows. However, top…”
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Thermal conductance across β-Ga2O3-diamond van der Waals heterogeneous interfaces by Cheng, Zhe, Yates, Luke, Shi, Jingjing, Tadjer, Marko J., Hobart, Karl D., Graham, Samuel

“…Because of its ultra-wide bandgap, high breakdown electric field, and large-area affordable substrates grown from the melt, β-Ga2O3 has attracted great…”
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Low Thermal Boundary Resistance Interfaces for GaN-on-Diamond Devices by Yates, Luke, Anderson, Jonathan, Gu, Xing, Lee, Cathy, Bai, Tingyu, Mecklenburg, Matthew, Aoki, Toshihiro, Goorsky, Mark S, Kuball, Martin, Piner, Edwin L, Graham, Samuel

“…The development of GaN-on-diamond devices holds much promise for the creation of high-power density electronics. Inherent to the growth of these devices, a…”
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Direct Visualization of Thermal Conductivity Suppression Due to Enhanced Phonon Scattering Near Individual Grain Boundaries by Sood, Aditya, Cheaito, Ramez, Bai, Tingyu, Kwon, Heungdong, Wang, Yekan, Li, Chao, Yates, Luke, Bougher, Thomas, Graham, Samuel, Asheghi, Mehdi, Goorsky, Mark, Goodson, Kenneth E

“…Understanding the impact of lattice imperfections on nanoscale thermal transport is crucial for diverse applications ranging from thermal management to energy…”
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Spatial pattern analysis of line‐segment data in ecology by Yates, Luke A., Brook, Barry W., Buettel, Jessie C.

“…The spatial analysis of linear features (lines and curves) is a challenging and rarely attempted problem in ecology. Existing methods are typically expressed…”
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Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1 by Feng, Tianshu, Yamamoto, Atsushi, Wilkins, Sarah E., Sokolova, Elizaveta, Yates, Luke A., Münzel, Martin, Singh, Pooja, Hopkinson, Richard J., Fischer, Roman, Cockman, Matthew E., Shelley, Jake, Trudgian, David C., Schödel, Johannes, McCullagh, James S.O., Ge, Wei, Kessler, Benedikt M., Gilbert, Robert J., Frolova, Ludmila Y., Alkalaeva, Elena, Ratcliffe, Peter J., Schofield, Christopher J., Coleman, Mathew L.

“…Efficient stop codon recognition and peptidyl-tRNA hydrolysis are essential in order to terminate translational elongation and maintain protein sequence…”
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Why some countries but not others? Urbanisation, GDP and endemic disease predict global SARS-CoV-2 excess mortality patterns by Fountain-Jones, Nicholas M., Charleston, Michael, Flies, Emily J., Carver, Scott, Yates, Luke A.

“…Context The global impact of the SARS-CoV-2 pandemic has been uneven, with some regions experiencing significant excess mortality while others have been…”
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A DNA damage-induced phosphorylation circuit enhances Mec1 ATR Ddc2 ATRIP recruitment to Replication Protein A by Yates, Luke A, Tannous, Elias A, Morgan, R Marc, Burgers, Peter M, Zhang, Xiaodong

“…The cell cycle checkpoint kinase Mec1 and its integral partner Ddc2 are vital for the DNA damage and replication stress response. Mec1-Ddc2…”
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