Search Results - "Yates, G."
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Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner
Published in Cell (05-03-2020)“…Cognitive dysfunction and reactive microglia are hallmarks of traumatic brain injury (TBI), yet whether these cells contribute to cognitive deficits and…”
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Systemic Immune Response to Traumatic CNS Injuries-Are Extracellular Vesicles the Missing Link?
Published in Frontiers in immunology (20-11-2019)“…Inflammation following traumatic injury to the central nervous system (CNS) persists long after the primary insult and is known to exacerbate cell death and…”
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Evaluating the effects of oseltamivir phosphate on platelet counts: a retrospective review
Published in Platelets (Edinburgh) (16-11-2020)“…Desialylation of platelets results in platelet clearance by the Ashwell-Morrell Receptors (AMR) found on hepatocytes. Studies suggest that oseltamivir…”
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Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury
Published in Journal of neuroinflammation (06-01-2021)“…The acute phase response (APR) to CNS insults contributes to the overall magnitude and nature of the systemic inflammatory response. Aspects of this response…”
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Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human
Published in Frontiers in physiology (30-07-2019)“…Preterm brain injury, occurring in approximately 30% of infants born <32 weeks gestational age, is associated with an increased risk of neurodevelopmental…”
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HDL and LDL have distinct, opposing effects on LPS-induced brain inflammation
Published in Lipids in health and disease (24-04-2023)“…Endotoxemia and sepsis induce neuroinflammation and increase the risk of neurodegenerative disorders although the mechanism by which peripheral infection leads…”
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Impaired cellulose decomposition in a headwater stream receiving subsurface agricultural drainage
Published in Ecological processes (01-12-2022)“…Background Agricultural development of former wetlands has resulted in many headwater streams being sourced by subsurface agricultural drainage systems…”
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Nafamostat reduces systemic inflammation in TLR7-mediated virus-like illness
Published in Journal of neuroinflammation (06-01-2022)“…The serine protease inhibitor nafamostat has been proposed as a treatment for COVID-19, by inhibiting TMPRSS2-mediated viral cell entry. Nafamostat has been…”
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Wound healing complications following folded flap palatoplasty in brachycephalic dogs
Published in Australian veterinary journal (01-12-2022)“…Objective To determine the incidence and characteristics of wound healing complications after folded flap palatoplasty (FFP). Methods Prospective study of 25…”
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The Biological Assessment and Rehabilitation of the World's Rivers: An Overview
Published in Water (Basel) (31-01-2021)“…The biological assessment of rivers i.e., their assessment through use of aquatic assemblages, integrates the effects of multiple-stressors on these systems…”
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Transfusion management of factor V deficiency: three case reports and review of the literature
Published in Transfusion (Philadelphia, Pa.) (01-07-2016)“…BACKGROUND Factor V (FV) deficiency may be inherited as an autosomal recessive disease or acquired as a result of autoantibody formation, either spontaneously…”
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AAV-vectored expression of monospecific or bispecific monoclonal antibodies protects mice from lethal Pseudomonas aeruginosa pneumonia
Published in Gene therapy (01-07-2024)“…Pseudomonas aeruginosa poses a significant threat to immunocompromised individuals and those with cystic fibrosis. Treatment relies on antibiotics, but…”
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Use of Advanced Flexible Modeling Approaches for Survival Extrapolation from Early Follow-up Data in two Nivolumab Trials in Advanced NSCLC with Extended Follow-up
Published in Medical decision making (01-01-2023)“…Objectives Immuno-oncology (IO) therapies are often associated with delayed responses that are deep and durable, manifesting as long-term survival benefits in…”
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Montelukast reduces grey matter abnormalities and functional deficits in a mouse model of inflammation-induced encephalopathy of prematurity
Published in Journal of neuroinflammation (29-10-2022)“…Encephalopathy of prematurity (EoP) affects approximately 30% of infants born < 32 weeks gestation and is highly associated with inflammation in the foetus…”
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Analysis of Thrombophilia Test Ordering Practices at an Academic Center: A Proposal for Appropriate Testing to Reduce Harm and Cost
Published in PloS one (13-05-2016)“…Ideally, thrombophilia testing should be tailored to the type of thrombotic event without the influence of anticoagulation therapy or acute phase effects which…”
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Volcanic glass properties from 1459 C.E. volcanic event in South Pole ice core dismiss Kuwae caldera as a potential source
Published in Scientific reports (08-10-2019)“…A large volcanic sulfate increase observed in ice core records around 1450 C.E. has been attributed in previous studies to a volcanic eruption from the…”
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Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression
Published in Translational psychiatry (25-11-2021)“…Lithium, a mood stabilizer and common adjunctive treatment for refractory depression, shares overlapping mechanisms of action with ketamine and enhances the…”
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Recombinant Newcastle disease viruses expressing immunological checkpoint inhibitors induce a pro-inflammatory state and enhance tumor-specific immune responses in two murine models of cancer
Published in Frontiers in microbiology (2024)“…Tumor microenvironments are immunosuppressive due to progressive accumulation of mutations in cancer cells that can drive expression of a range of inhibitory…”
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Intranasal vaccination with an NDV-vectored SARS-CoV-2 vaccine protects against Delta and Omicron challenges
Published in npj vaccines (23-05-2024)“…The rapid development and deployment of vaccines following the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been estimated to…”
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Boron isotopic composition of tourmaline, prismatine, and grandidierite from granulite facies paragneisses in the Larsemann Hills, Prydz Bay, East Antarctica: Evidence for a non-marine evaporite source
Published in Geochimica et cosmochimica acta (01-12-2013)“…A unique assemblage of B-rich rocks (<2 wt.% B) containing the borosilicate minerals tourmaline (Tur), prismatine (Prs) and grandidierite (Gdd) is exposed in…”
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