Search Results - "Yasukochi, T"

Characterisation of Th1/Th2 type, glucose-6-phosphate isomerase reactive T cells in the generation of rheumatoid arthritis by Kori, Y, Matsumoto, I, Zhang, H, Yasukochi, T, Hayashi, T, Iwanami, K, Goto, D, Ito, S, Tsutsumi, A, Sumida, T

“…[...]our findings suggest that GPI reactive IFN[GAMMA]+/IL4+ T cells may have a crucial role in the generation of arthritis in HLA-DRB1*0405 or *0901 positive…”
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Defuzzified clustering algorithms derived from the method of entropy-based fuzzy c-means by Miyamoto, S., Yasukochi, T., Inokuchi, R.

“…A class of hard c-means algorithms is derived from 'defuzzifying' objective functions of the entropy-based fuzzy c-means and the KL-information based fuzzy…”
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Chemoenzymatic Synthesis of a Trisaccharide–Serine Conjugate, Gal(β1-3)Gal(β1-4)Xyl(β1-O)–L-Ser, Use of Galactosyl Fluoride as a Donor for Transglycosylation by Fukase, Koichi, Yasukochi, Takashi, Kusumoto, Shoichi

“…The trisaccharide–serine conjugate [Gal(β1-3)Gal(β1-4)Xyl(β)-Ser], constituting the linkage region between the glycosaminoglycan and protein in proteoglycan,…”
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A Mutation Study of Catalytic Residue Asp 52 in Hen Egg Lysozyme by Hashimoto, Yoshio, Yamada, Keiko, Motoshima, Hiroyuki, Omura, Tadahiro, Yamada, Hidenori, Yasukochi, Takanori, Miki, Takeyoshi, Ueda, Tadashi, Imoto, Taiji

“…We constructed a system for the expression and secretion of mature hen lysozyme by yeast using an intermediate “secretion-signal cassette” vector, pKP1700,…”
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Macrophage Activation in Response to S-Form Lipopolysaccharides (LPS) Separated by Centrifugal Partition Chromatography from Wild-Type LPS: Effects of the O-Polysaccharide Portion of LPS by Suda, Y., Kirikae, T., Shiyama, T., Yasukochi, T., Kirikae, F., Nakano, M., Rietschel, E.T., Kusumoto, S.

“…The S-form lipopolysaccharide (LPS) was effectively separated from a native preparation of smooth-type Salmonella abortus equi LPS by means of the centrifugal…”
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Improvement of IGCR technique using FRET by Yasukochi, T, Ooyama, A, Kumazawa, H, Kawanabe, J, Ozawa, K, Shibanaka, Y

“…The fluorescent detection system has been introduced into the study on denaturation/reassociation process of DNA fragments in gel, for improving In-Gel…”
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Therapeutic effects of antibodies to tumor necrosis factor-alpha, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis by Matsumoto, Isao, Zhang, Hua, Yasukochi, Takanori, Iwanami, Keiichi, Tanaka, Yoko, Inoue, Asuka, Goto, Daisuke, Ito, Satoshi, Tsutsumi, Akito, Sumida, Takayuki

“…Immunization with glucose-6-phosphate isomerase (GPI) induces severe arthritis in DBA/1 mice. The present study was designed to identify the cytokines and…”
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New quantitative analysis of fibrinolytic activity by 1 dimensional diffusion. 1. Fibrinolytic activity of plasmin and "euglobulin plus streptokinase" by Yasukochi, T

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Nitropyridyl glycosides: new glycosyl donors for enzymatic transglycosylation by Yasukochi, Takashi, Inaba, Chikako, Fukase, Koichi, Kusumoto, Shoichi

“…New glycosyl donors, 3-nitro-2-pyridyl and 5-nitro-2-pyridyl glycosides, proved to be effective for transglycosylation reaction catalyzed by glycosidases, such…”
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Antifibrinolytic factor by Yasukochi, T, Nakagawa, S

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3-Nitro-2-pyridyl glycoside as donor for chemical glycosylation and its application to chemoenzymatic synthesis of oligosaccharide by Yasukochi, Takashi, Fukase, Koichi, Kusumoto, Shoichi

“…3-Nitro-2-pyridyl (3NPy) glycosides, which act as versatile glycosyl donors in enzymatic transglycosylation, can also be chemically activated. Chemical…”
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A functional variant of Fcγ receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies by Matsumoto, Isao, Zhang, Hua, Muraki, Yoshifumi, Hayashi, Taichi, Yasukochi, Takanori, Kori, Yuko, Goto, Daisuke, Ito, Satoshi, Tsutsumi, Akito, Sumida, Takayuki

“…Anti-glucose-6-phosphate isomerase (GPI) antibodies are known to be arthritogenic autoantibodies in K/B×N mice, although some groups have reported that few…”
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A column gel electrophoresis-coupled genomic DNA subtractive hybridization technique by Ozawa, Kazuo, McElgunn, Cathal J., Yasukochi, Takanori, Shibanaka, Yasuhiko

“…We have developed a DNA subtractive hybridization technique especially designed for mammalian genome comparison. The core of this protocol is a newly devised…”
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Immunoglobulin G from anti-glucose-6-phosphate isomerase antibodies positive patient with rheumatoid arthritis induces synovitis in cynomolgus monkeys by Suzuki, Takeshi, Muraki, Yoshifumi, Yasukochi, Takanori, Zhang, Hua, Kori, Yuko, Wakamatsu, Ei, Hayashi, Taichi, Goto, Daisuke, Ito, Satoshi, Tsutsumi, Akito, Sumichika, Hiroshi, Sumida, Takayuki, Matsumoto, Isao

“…Anti-glucose-6-phosphate isomerase (GPI) antibodies (Abs) solely induce arthritis in mice. High titers of anti-GPI Abs are found in some patients with…”
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The exploration of joint-specific immunoreactions on immunoglobulins G of anti-glucose-6-phosphate isomerase antibody-positive patients with rheumatoid arthritis by Matsumoto, Isao, Muraki, Yoshifumi, Yasukochi, Takanori, Hua, Zhang, Kori, Yuko, Hayashi, Taichi, Goto, Daisuke, Ito, Satoshi, Tsutsumi, Akito, Ikeda, Kotaro, Sumichika, Hiroshi, Sumida, Takayuki

“…The pathogenic role of autoantibodies in rheumatoid arthritis (RA) remains elusive. Anti-glucose-6-phosphate isomerase (GPI) antibodies (Abs) are candidates…”
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Multiple role of hydrophobicity of tryptophan-108 in chicken lysozyme: structural stability, saccharide binding ability, and abnormal pKa of glutamic acid-35 by Inoue, Makoto, Yamada, Hidenori, Yasukochi, Takanori, Kuroki, Ryota, Miki, Takeyoshi, Horiuchi, Tadao, Imoto, Taiji

“…Trp108 of chicken lysozyme is in van der Waals contact with Glu35, one of two catalytic carboxyl groups. The role of Trp108 in lysozyme function and stability…”
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Chemoenzymatic synthesis of Gal(β1-3)Gal(β1-4)Xyl(β)- l-Ser and Gal(β1-3)Gal(β1-4)Xyl(β)-MU by the use of β- d-galactosidase by Fukase, Koichi, Yasukochi, Takashi, Suda, Yasuo, Yoshida, Masao, Kusumoto, Shoichi

“…The title trisaccharide-serine conjugate 1 constituting the linkage region between glycosaminoglycan and protein in proteoglycan, was synthesized via a…”
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Analysis of abnormally expressed genes in synovium from patients with rheumatoid arthritis using a column gel electrophoresis-coupled subtractive hybridization technique by Tomoo, Takashi, Tsutsumi, Akito, Yasukochi, Takanori, Ikeda, Kotaro, Ochiai, Naoyuki, Ozawa, Kazuo, Shibanaka, Yasuhiko, Ito, Satoshi, Matsumoto, Isao, Goto, Daisuke, Sumida, Takayuki

“…Rheumatoid arthritis (RA) is a chronic disease of unknown pathogenesis. To identify abnormally expressed genes in synovium from RA patients, we performed…”
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p-Nitrophenyl group for anomeric protection of oligosaccharides, selective oxidative cleavage via p-acetamidophenyl glycosides by Fukase, Koichi, Yasukochi, Takashi, Nakai, Yoshihiko, Kusumoto, Shoichi

“…Versatile use of the p-nitrophenyl group for anomeric protection of carbohydrates is described. It can be readily removed via conversion into a…”
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Enzymatic Synthesis of 4-Methylumbelliferyl Glycosides of Trisaccharide and Core Tetrasaccharide, Gal(β1-3)Gal(β1-4)Xyl and GlcA(β1-3)Gal(β1-3)Gal(β1-4)Xyl, Corresponding to the Linkage Region of Proteoglycans by Yasukochi, Takashi, Fukase, Koichi, Suda, Yasuo, Takagaki, Keiichi, Endo, Masahiko, Kusumoto, Shoichi

“…Fluorescence labeled trisaccharide, Gal(β1-3)Gal(β1-4)Xyl(β)–MU [MU = 4-methyl-2-oxo-2H-chromen-7-yl (4-methylumbelliferyl)], and tetrasaccharide,…”
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