Search Results - "Yasui, Yuko"

SIGMAR1 Confers Innate Resilience against Neurodegeneration by Couly, Simon, Yasui, Yuko, Su, Tsung-Ping

“…The sigma-1 receptor (SIGMAR1) is one of a kind: a receptor chaperone protein. This 223 amino acid-long protein is enriched at the mitochondria-associated…”
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Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion by Nakamura, Yoki, Dryanovski, Dilyan I, Kimura, Yuriko, Jackson, Shelley N, Woods, Amina S, Yasui, Yuko, Tsai, Shang-Yi, Patel, Sachin, Covey, Daniel P, Su, Tsung-Ping, Lupica, Carl R

“…Cocaine is an addictive drug that acts in brain reward areas. Recent evidence suggests that cocaine stimulates synthesis of the endocannabinoid…”
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Knocking Out Sigma-1 Receptors Reveals Diverse Health Problems by Couly, Simon, Goguadze, Nino, Yasui, Yuko, Kimura, Yuriko, Wang, Shao-Ming, Sharikadze, Nino, Wu, Hsiang-En, Su, Tsung-Ping

“…Sigma-1 receptor (Sig-1R) is a protein present in several organs such as brain, lung, and heart. In a cell, Sig-1R is mainly located across the membranes of…”
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Establishment and characterization of a non-gestational choriocarcinoma patient-derived xenograft model by Oda, Yukari, Niimi, Kaoru, Yoshida, Kosuke, Tamauchi, Satoshi, Yokoi, Akira, Yasui, Yuko, Nishiko, Yuki, Shibata, Mayu, Shimizu, Yusuke, Yoshihara, Masato, Ikeda, Yoshiki, Yoshikawa, Nobuhisa, Nishino, Kimihiro, Yamamoto, Eiko, Kajiyama, Hiroaki

“…Abstract Background Non-gestational choriocarcinoma (NGC) is a rare subtype of malignant germ cell tumour and there is no consensus on its treatment. The lack…”
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Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain by Wang, Shao-Ming, Goguadze, Nino, Kimura, Yuriko, Yasui, Yuko, Pan, Bin, Wang, Tzu-Yun, Nakamura, Yoki, Lin, Yu-Ting, Hogan, Quinn H., Wilson, Katherine L., Su, Tsung-Ping, Wu, Hsiang-en

“…Sigma-1 receptors (Sig-1Rs) are endoplasmic reticulum (ER) chaperones implicated in neuropathic pain. Here we examine if the Sig-1R may relate to neuropathic…”
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Correction to: Genomic Action of Sigma-1 Receptor Chaperone Relates to Neuropathic Pain by Wang, Shao-Ming, Goguadze, Nino, Kimura, Yuriko, Yasui, Yuko, Pan, Bin, Wang, Tzu-Yun, Nakamura, Yoki, Lin, Yu-Ting, Hogan, Quinn H., Wilson, Katherine L., Su, Tsung-Ping, Wu, Hsiang-en

“…A correction to this paper has been published: 10.1007/s12035-021-02310-3…”
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Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr by Kitamori, Kazuya, Naito, Hisao, Tamada, Hazuki, Kobayashi, Miya, Miyazawa, Daisuke, Yasui, Yuko, Sonoda, Kunihiro, Tsuchikura, Satoru, Yasui, Naomi, Ikeda, Katsumi, Moriya, Takashi, Yamori, Yukio, Nakajima, Tamie

“…Patients with nonalcoholic fatty liver disease are increasing worldwide, and preventive measures are an urgent need and primary concern today. This study aimed…”
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PMA-induced GCMa phosphorylation stimulates its transcriptional activity and degradation by Yasui, Yuko, Miyazawa, Daisuke, Ueda, Hiroshi, Sato, Katsuya, Kitade, Yukio, Yamada, Kazuyo

“…Glial cells missing Drosophila homolog a (GCMa) is a member of the GCM transcription factor family and plays critical roles in trophoblast differentiation and…”
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Biochemical responses to dietary α-linolenic acid restriction proceed differently among brain regions in mice by Miyazawa, Daisuke, Yasui, Yuko, Yamada, Kazuyo, Ohara, Naoki, Okuyama, Harumi

“…Previously, we noted that the dietary restriction of α-linolenic acid (ALA, n-3) for 4 weeks after weaning brought about significant decreases in the BDNF…”
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Testosterone-lowering activity of canola and hydrogenated soybean oil in the stroke-prone spontaneously hypertensive rat by Okuyama, Harumi, Ohara, Naoki, Tatematsu, Kenjiro, Fuma, Shinya, Nonogaki, Tomoyuki, Yamada, Kazuyo, Ichikawa, Yuko, Miyazawa, Daisuke, Yasui, Yuko, Honma, Seijiro

“…Canola and some other types of oil unusually shorten the survival of stroke-prone spontaneously hypertensive rats (SHRSP), compared with soybean oil, perilla…”
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Establishment of MTX-resistant cell lines of choriocarcinoma and search for therapeutic agents by drug repositioning by Nishiko, Yuki, Niimi, Kaoru, Yasui, Yuko, Yoshida, Kosuke, Nishino, Kimihiro, Yamamoto, Eiko, Kajiyama, Hiroaki

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Benzomorphan and non-benzomorphan agonists differentially alter sigma-1 receptor quaternary structure, as does types of cellular stress by Couly, Simon, Yasui, Yuko, Foncham, Semnyonga, Grammatikakis, Ioannis, Lal, Ashish, Shi, Lei, Su, Tsung-Ping

“…Sigma-1 receptor (S1R) is a calcium-sensitive, ligand-operated receptor chaperone present on the endoplasmic reticulum (ER) membrane. S1R plays an important…”
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Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine by Wang, Shao-Ming, Wu, Hsiang-En, Yasui, Yuko, Geva, Michal, Hayden, Michael, Maurice, Tangui, Cozzolino, Mauro, Su, Tsung-Ping

“…Macroautophagy/autophagy is an essential process for cellular survival and is implicated in many diseases. A critical step in autophagy is the transport of the…”
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Unique genomic profiles of choriocarcinoma based on whole exome sequencing analysis by Oda, Yukari, Niimi, Kaoru, Yasui, Yuko, Nishiko, Yuki, Shibata, Mayu, Nishino, Kimihiro, Yamamoto, Eiko, Kajiyama, Hiroaki

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Establishment and application of MTX-resistant choriocarcinoma cell lines by Nishiko, Yuki, Niimi, Kaoru, Yosida, Kosuke, Imagawa, Takuya, Yasui, Yuko, Shibata, Mayu, Oda, Yukari, Nishino, Kimihiro, Yamamoto, Eiko, Kajiyama, Hiroaki

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RNA sequencing reveals XBP1 as a novel factor contributing to the progression of post-molar GTN by Shibata, Mayu, Niimi, Kaoru, Yoshida, Kousuke, Imagawa, Takuya, Yasui, Yuko, Nishiko, Yuki, Oda, Yukari, Nishino, Kimihiro, Yamamoto, Eiko, Kajiyama, Hiroaki

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Elucidation of the role of XBP1 in the progression of complete hydatidiform mole to invasive mole through RNA-seq by Shibata, Mayu, Yoshida, Kosuke, Yokoi, Akira, Suzuki, Hironori, Yamamoto, Yusuke, Kitagawa, Masami, Asano-Inami, Eri, Yasui, Yuko, Nishiko, Yuki, Yoshihara, Masato, Tamauchi, Satoshi, Yoshikawa, Nobuhisa, Nishino, Kimihiro, Yamamoto, Eiko, Niimi, Kaoru, Kajiyama, Hiroaki

“…A complete hydatidiform mole (CHM) is a common disease and is known to develop post-molar gestational trophoblast neoplasia (GTN). However, the molecular…”
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Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models by Crouzier, Lucie, Danese, Alberto, Yasui, Yuko, Richard, Elodie M, Liévens, Jean-Charles, Patergnani, Simone, Couly, Simon, Diez, Camille, Denus, Morgane, Cubedo, Nicolas, Rossel, Mireille, Thiry, Marc, Su, Tsung-Ping, Pinton, Paolo, Maurice, Tangui, Delprat, Benjamin

“…The Wolfram syndrome is a rare autosomal recessive disease affecting many organs with life-threatening consequences; currently, no treatment is available. The…”
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Identification of novel therapeutic agents for choriocarcinoma based on drug repositioning strategies by Yoshida, Kosuke, Watanabe, Eri, Imagawa, Takuya, Yasui, Yuko, Nishiko, Yuki, Shibata, Mayu, Oda, Yukari, Nishino, Kimihiro, Yamamoto, Eiko, Niimi, Kaoru, Kajiyama, Hiroaki

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Dietary soybean oil, canola oil and partially-hydrogenated soybean oil affect testicular tissue and steroid hormone levels differently in the miniature pig by Miyazawa, Daisuke, Ohara, Naoki, Yamada, Kazuyo, Yasui, Yuko, Kitamori, Kazuya, Saito, Yoshiaki, Usumi, Kenji, Nagata, Tomoko, Nonogaki, Tsunemasa, Hashimoto, Yoko, Miyashiro, Yoshimichi, Homma, Seijiro, Okuyama, Harumi

“…The present study was conducted to examine the influence of dietary canola oil (CAN) and partially-hydrogenated soybean oil (HSO) compared to soybean oil (SOY,…”
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