Search Results - "Yasuhiko Irie"

Discovery and development of safe-in-man broad-spectrum antiviral agents by Andersen, Petter I., Ianevski, Aleksandr, Lysvand, Hilde, Vitkauskiene, Astra, Oksenych, Valentyn, Bjørås, Magnar, Telling, Kaidi, Lutsar, Irja, Dumpis, Uga, Irie, Yasuhiko, Tenson, Tanel, Kantele, Anu, Kainov, Denis E.

“…•We reviewed the discovery and development process of broad-spectrum antiviral agents.•We summarized the information on 120 safe-in-man agents in a freely…”
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Black Queen Hypothesis, partial privatization, and quorum sensing evolution by Souza, Lucas Santana, Irie, Yasuhiko, Eda, Shigetoshi

“…Microorganisms produce costly cooperative goods whose benefit is partially shared with nonproducers, called 'mixed' goods. The Black Queen Hypothesis predicts…”
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Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange by Hmelo, Laura R, Borlee, Bradley R, Almblad, Henrik, Love, Michelle E, Randall, Trevor E, Tseng, Boo Shan, Lin, Chuyang, Irie, Yasuhiko, Storek, Kelly M, Yang, Jaeun Jane, Siehnel, Richard J, Howell, P Lynne, Singh, Pradeep K, Tolker-Nielsen, Tim, Parsek, Matthew R, Schweizer, Herbert P, Harrison, Joe J

“…Here, the authors describe genetically engineering the Pseudomonas genome by two-step allelic exchange. Suicide vector-encoded alleles are used to generate…”
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The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix by Colvin, Kelly M., Irie, Yasuhiko, Tart, Catherine S., Urbano, Rodolfo, Whitney, John C., Ryder, Cynthia, Howell, P. Lynne, Wozniak, Daniel J., Parsek, Matthew R.

“…Summary Extracellular polysaccharides comprise a major component of the biofilm matrix. Many species that are adept at biofilm formation have the capacity to…”
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Self-produced exopolysaccharide is a signal that stimulates biofilm formation in Pseudomonas aeruginosa by Irie, Yasuhiko, Borlee, Bradley R, O’Connor, Jennifer R, Hill, Preston J, Harwood, Caroline S, Wozniak, Daniel J, Parsek, Matthew R

“…Bacteria have a tendency to attach to surfaces and grow as structured communities called biofilms. Chronic biofilm infections are a problem because they tend…”
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Role of Multicellular Aggregates in Biofilm Formation by Kragh, Kasper N, Hutchison, Jaime B, Melaugh, Gavin, Rodesney, Chris, Roberts, Aled E L, Irie, Yasuhiko, Jensen, Peter Ø, Diggle, Stephen P, Allen, Rosalind J, Gordon, Vernita, Bjarnsholt, Thomas

“…In traditional models ofin vitrobiofilm development, individual bacterial cells seed a surface, multiply, and mature into multicellular, three-dimensional…”
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Pseudomonas aeruginosa biofilm matrix polysaccharide Psl is regulated transcriptionally by RpoS and post-transcriptionally by RsmA by Irie, Yasuhiko, Starkey, Melissa, Edwards, Adrianne N, Wozniak, Daniel J, Romeo, Tony, Parsek, Matthew R

“…Extracellular polysaccharides are important components of biofilms. In non-mucoid Pseudomonas aeruginosa strains, the Pel and Psl polysaccharides are major…”
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Fluorescence-Based Reporter for Gauging Cyclic Di-GMP Levels in Pseudomonas aeruginosa by RYBTKE, Morten T, BORLEE, Bradley R, MURAKAMI, Keiji, IRIE, Yasuhiko, HENTZER, Morten, NIELSEN, Thomas E, GIVSKOV, Michael, PARSEK, Matthew R, TOLKER-NIELSEN, Tim

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Shaping the Growth Behaviour of Biofilms Initiated from Bacterial Aggregates by Melaugh, Gavin, Hutchison, Jaime, Kragh, Kasper Nørskov, Irie, Yasuhiko, Roberts, Aled, Bjarnsholt, Thomas, Diggle, Stephen P, Gordon, Vernita D, Allen, Rosalind J

“…Bacterial biofilms are usually assumed to originate from individual cells deposited on a surface. However, many biofilm-forming bacteria tend to aggregate in…”
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ChIP-Seq and RNA-Seq reveal an AmrZ-mediated mechanism for cyclic di-GMP synthesis and biofilm development by Pseudomonas aeruginosa by Jones, Christopher J, Newsom, David, Kelly, Benjamin, Irie, Yasuhiko, Jennings, Laura K, Xu, Binjie, Limoli, Dominique H, Harrison, Joe J, Parsek, Matthew R, White, Peter, Wozniak, Daniel J

“…The transcription factor AmrZ regulates genes important for P. aeruginosa virulence, including type IV pili, extracellular polysaccharides, and the flagellum;…”
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Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections by Harrison, Joe J, Almblad, Henrik, Irie, Yasuhiko, Wolter, Daniel J, Eggleston, Heather C, Randall, Trevor E, Kitzman, Jacob O, Stackhouse, Bethany, Emerson, Julia C, Mcnamara, Sharon, Larsen, Tyler J, Shendure, Jay, Hoffman, Lucas R, Wozniak, Daniel J, Parsek, Matthew R

“…Pseudomonas aeruginosa colonizes the airways of cystic fibrosis (CF) patients, causing infections that can last for decades. During the course of these…”
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Hfq-Assisted RsmA Regulation Is Central to Pseudomonas aeruginosa Biofilm Polysaccharide PEL Expression by Irie, Yasuhiko, La Mensa, Agnese, Murina, Victoriia, Hauryliuk, Vasili, Tenson, Tanel, Shingler, Victoria

“…To appropriately switch between sessile and motile lifestyles, bacteria control expression of biofilm-associated genes through multiple regulatory elements. In…”
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Evolutionary adaptations of biofilms infecting cystic fibrosis lungs promote mechanical toughness by adjusting polysaccharide production by Kovach, Kristin, Davis-Fields, Megan, Irie, Yasuhiko, Jain, Kanishk, Doorwar, Shashvat, Vuong, Katherine, Dhamani, Numa, Mohanty, Kishore, Touhami, Ahmed, Gordon, Vernita D

“…Biofilms are communities of microbes embedded in a matrix of extracellular polymeric substances, largely polysaccharides. Multiple types of extracellular…”
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The cabABC Operon Essential for Biofilm and Rugose Colony Development in Vibrio vulnificus by Park, Jin Hwan, Jo, Youmi, Jang, Song Yee, Kwon, Haenaem, Irie, Yasuhiko, Parsek, Matthew R, Kim, Myung Hee, Choi, Sang Ho

“…A transcriptome analysis identified Vibrio vulnificus cabABC genes which were preferentially expressed in biofilms. The cabABC genes were transcribed as a…”
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Carbohydrates from Pseudomonas aeruginosa biofilms interact with immune C-type lectins and interfere with their receptor function by Singh, Sonali, Almuhanna, Yasir, Alshahrani, Mohammad Y., Lowman, Douglas W., Rice, Peter J., Gell, Chris, Ma, Zuchao, Graves, Bridget, Jackson, Darryl, Lee, Kelly, Juarez, Rucha, Koranteng, Janice, Muntaka, Sirina, Daniel A. Mitchell, da Silva, Ana C., Hussain, Farah, Yilmaz, Gokhan, Mastrotto, Francesca, Irie, Yasuhiko, Williams, Paul, Williams, David L., Cámara, Miguel, Martinez-Pomares, Luisa

“…Bacterial biofilms represent a challenge to the healthcare system because of their resilience against antimicrobials and immune attack. Biofilms consist of…”
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Explorative gene analysis of antibiotic tolerance-related genes in adherent and biofilm cells of Pseudomonas aeruginosa by Murakami, Keiji, Ono, Tsuneko, Noma, Yasuki, Minase, Issei, Amoh, Takashi, Irie, Yasuhiko, Hirota, Katsuhiko, Miyake, Yoichiro

“…Abstract Background Antibiotic tolerance has attracted worldwide attention, as it leads to chronic, refractory, and persistent infections that are difficult to…”
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The Bvg Virulence Control System Regulates Biofilm Formation in Bordetella bronchiseptica by IRIE, Yasuhiko, MATTOO, Seema, YUK, Ming H

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Pseudomonas aeruginosa Quorum-Sensing autoinducer analog enhances the activity of antibiotics against resistant strains by Amoh, Takashi, Murakami, Keiji, Kariyama, Reiko, Hori, Kenji, Irie, Yasuhiko, Viducic, Darija, Hirota, Katsuhiko, Igarashi, Jun, Suga, Hiroaki, Kumon, Hiromi, Miyake, Yoichiro

“…In this study, we have investigated the effects of the newly synthesized analog of Pseudomonas aeruginosa quorum-sensing autoinducer named AIA-1 (autoinducer…”
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Correction: The cabABC Operon Essential for Biofilm and Rugose Colony Development in Vibrio vulnificus by Park, Jin Hwan, Jo, Youmi, Jang, Song Yee, Kwon, Haenaem, Irie, Yasuhiko, Parsek, Matthew R, Kim, Myung Hee, Choi, Sang Ho

“…[This corrects the article DOI: 10.1371/journal.ppat.1005192.]…”
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Expression of the Primary Carbohydrate Component of the Bordetella bronchiseptica Biofilm Matrix Is Dependent on Growth Phase but Independent of Bvg Regulation by IRIE, Yasuhiko, PRESTON, Andrew, YUK, Ming H

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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