Search Results - "Yasuhiko HIGASHI"

Simultaneous liquid chromatographic assay of amantadine and its four related compounds in phosphate-buffered saline using 4-fluoro-7-nitro-2,1,3-benzoxadiazole as a fluorescent derivatization reagent by Higashi, Yasuhiko, Nakamura, Shota, Matsumura, Hiroki, Fujii, Youichi

“…Simultaneous HPLC assay of 1‐adamantanamine hydrochloride (amantadine) and its four related compounds [2‐adamantanamine hydrochloride (2‐ADA),…”
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Selective Delivery of Estradiol to Bone by Aspartic Acid Oligopeptide and Its Effects on Ovariectomized Mice by Yokogawa, Koichi, Miya, Kazuhiro, Sekido, Tohru, Higashi, Yasuhiko, Nomura, Masaaki, Fujisawa, Ryuichi, Morito, Keiko, Masamune, Yukito, Waki, Yoshihiro, Kasugai, Shohei, Miyamoto, Ken-ichi

“…We have developed a novel osteotropic prodrug of estradiol (E2) conjugated with l-Asp-hexapeptide (E2·3D6), which has very low affinity for estrogen receptors,…”
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Liquid chromatographic determination of 1-adamantanamine and 2-adamantanamine in human plasma after pre-column derivatization with o-phthalaldehyde and 1-thio-β- d-glucose by Higashi, Yasuhiko, Fujii, Youichi

“…We investigated high-performance liquid chromatographic (HPLC) determination of 1-adamantanamine hydrochloride (1-ADA) and 2-adamantanamine hydrochloride…”
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Sensitive Determination of 4-(4-Bromophenyl)-4-hydroxypiperidine, a Metabolite of Bromperidol, in Rat Plasma by HPLC with Fluorescence Detection after Pre-column Derivatization Using 4-Fluoro-7-nitro-2,1,3-benzoxadiazole by Higashi, Yasuhiko, Nakamura, Shota, Fujii, Youichi

“…The purpose of this study was to determine the level of 4-(4-bromophenyl)-4-hydroxypiperidine (BPHP), a bromperidol (BRO) metabolite, in rat plasma by HPLC…”
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Modulation of mdr1a and CYP3A gene expression in the intestine and liver as possible cause of changes in the cyclosporin A disposition kinetics by dexamethasone by Yokogawa, Koichi, Shimada, Tsutomu, Higashi, Yasuhiko, Itoh, Yoshie, Masue, Toshiko, Ishizaki, Junko, Asahi, Mariko, Miyamoto, Ken-ichi

“…We investigated the effect of dexamethasone (DEX) on the disposition kinetics of cyclosporin A (CyA) and the mechanism of this drug interaction. Rats were…”
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Simple HPLC–fluorescence determination of eugenol in clove oil after pre-column derivatization with 4-(N-chloroformylmethyl-Nmethylamino)-7-nitro-2,1,3-benzoxadiazole by Higashi, Yasuhiko

“…Eugenol is a phenolic flavor constituent of various plants, including clove and cinnamon. Eugenol content in clove oil has been analyzed by HPLC–UV after…”
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Decreased tissue distribution of L-carnitine in juvenile visceral steatosis mice by Yokogawa, K, Higashi, Y, Tamai, I, Nomura, M, Hashimoto, N, Nikaido, H, Hayakawa, J, Miyamoto, K, Tsuji, A

“…We kinetically analyzed the disposition of L-carnitine of juvenile visceral steatosis (JVS) mice compared with that of normal mice to elucidate the mechanism…”
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Pharmacokinetic Study of β-Methyldigoxin by Enzyme Immunoassay Using a Novel Specific Antiserum in Rats by Higashi, Yasuhiko, Watanabe, Naomi, Sasaki, Toshiyuki, Fujii, Youichi

“…We previously showed that enzyme immunoassay (EIA) of β-methyldigoxin (MDx3) using anti-MDx3 3′-hemisuccinate–bovine serum albumin antiserum (Antiserum-I) was…”
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Establishment of Enzyme Immunoassay for Measuring β-Methyldigoxin Levels in Human Serum by Specific Antiserum by Higashi, Yasuhiko, Watanabe, Naomi, Sasaki, Toshiyuki, Fujii, Youichi

“…We investigated the specificity of obtained antisera to β-methyldigoxin by the enzyme immunoassay. Three types of hapten-bovine serum albumin (BSA) conjugates…”
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In vitro inhibition of α-glucosidases and glycogen phosphorylase by catechin gallates in green tea by Kamiyama, Ogusa, Sanae, Fujiko, Ikeda, Kyoko, Higashi, Yasuhiko, Minami, Yasuhiro, Asano, Naoki, Adachi, Isao, Kato, Atsushi

“…We investigated in vitro inhibition of mammalian carbohydrate-degrading enzymes by green tea extract and the component catechins, and further evaluated their…”
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Determination of three phenylphenols in grapefruit juice by HPLC after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole by Higashi, Yasuhiko, Fujii, Youichi

“…o -Phenylphenol is generally utilized as a disinfectant for citrus fruits. The purpose of this study is to develop a high-performance liquid chromatography…”
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Simple determination of o-phenylphenol in skin lotion by high-performance liquid chromatography coupled with fluorescence detection after pre-column derivatization with 4-(N-chloroformylmethyl-N-methylamino)-7-nitro-2,1,3-benzoxadiazole by Higashi, Yasuhiko, Konno, Kazunori

“…o-Phenylphenol (OPP) in skin lotion was quantitated by high-performance liquid chromatography coupled with fluorescence detection after pre-column…”
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Sensitive Determination of 4-(4-Bromophenyl)-4-hydroxypiperidine, a Metabolite of Bromperidol, in Rat Plasma by HPLC with Fluorescence Detection after Pre-column Derivatization Using 4-Fluoro-7-nitro-2,1,3-benzoxadiazole by Yasuhiko HIGASHI, Shota NAKAMURA, Youichi FUJII

“…The purpose of this study was to determine the level of 4-(4-bromophenyl)-4-hydroxypiperidine (BPHP), a bromperidol (BRO) metabolite, in rat plasma by HPLC…”
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HPLC-UV ANALYSIS OF EUGENOL IN CLOVE AND CINNAMON OILS AFTER PRE-COLUMN DERIVATIZATION WITH 4-FLUORO-7-NITRO-2,1,3-BENZOXADIAZOLE by Higashi, Yasuhiko, Fujii, Youichi

“…Eugenol is one of the flavor constituents in various medicinally used plant oils, such as clove and cinnamon oils, which are widely used as flavoring agents in…”
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Determination of kojic acid in a skin-whitening cosmetic by high-performance liquid chromatography coupled with ultraviolet detection after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole by Higashi, Yasuhiko, Fujii, Youichi

“…Various methods for the determination of kojic acid (KA), a skin-whitening agent, have been reported by high-performance liquid chromatography (HPLC). In this…”
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Determination of hinokitiol in skin lotion by high-performance liquid chromatography-ultraviolet detection after precolumn derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole by Higashi, Yasuhiko, Fujii, Youichi

“…Hinokitiol, a potent, broad-spectrum antibacterial agent, is a component of various personal care products. In this study, the concentration of hinokitiol in…”
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Pharmacokinetic Study of β-Methyldigoxin by Enzyme Immunoassay Using a Novel Specific Antiserum in Rats by Yasuhiko HIGASHI, Naomi WATANABE, Toshiyuki SASAKI, Youichi FUJII

“…We previously showed that enzyme immunoassay (EIA) of β-methyldigoxin (MDX3) using anti-MDx3 3'-hemisuccinate-bovine serum albumin antiserum (Antiserum-I) was…”
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HPLC-UV Analysis of Phenol and Chlorophenols in Water After Precolumn Derivatization with 4-Fluoro-7-nitro-2,1,3-benzoxadiazole by Higashi, Yasuhiko, Fujii, Youichi

“…Chlorophenols (2-chlorophenol, 4-chlorophenol, 2,4-dichlorophenol, 2,6-dichlorophenol, and 2,4,6-trichlorophenol) are present in drinking water and tap water…”
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Characteristics of L-Carnitine Transport in Cultured Human Hepatoma HLF Cells by Yokogawa, Koichi, Miya, Kazuhiro, Tamai, Ikumi, Higashi, Yasuhiko, Nomura, Masaaki, Miyamoto, Ken-Ichi, Tsuji, Akira

“…The recently cloned organic cation transporter, OCTN2, isolated as a homologue of OCTN1, has been shown to be of physiological importance in the renal tubular…”
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Effects of eugenol-reduced clove extract on glycogen phosphorylase b and the development of diabetes in db/db mice by Sanae, Fujiko, Kamiyama, Ogusa, Ikeda-Obatake, Kyoko, Higashi, Yasuhiko, Asano, Naoki, Adachi, Isao, Kato, Atsushi

“…We found that the 50% aqueous EtOH extract of clove (Syzygium aromaticum) had potent dose-dependent inhibitory activity toward glycogen phosphorylase b and…”
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