Search Results - "Yasuba, Hirotaka"

Cycling therapy with benralizumab and dupilumab for severe eosinophilic asthma with eosinophilic chronic rhinosinusitis and eosinophilic otitis media by Hamada, Satoshi, Ogino, Eriko, Yasuba, Hirotaka

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Role of eosinophilic chronic rhinosinusitis in switching to benralizumab treatment in mepolizumab responders by Hamada, Satoshi, Kobayashi, Yoshiki, Yasuba, Hirotaka

“…There are currently three anti-interleukin-5 (IL-5) pathway-directed therapies: mepolizumab, reslizumab, and benralizumab. Of these, benralizumab was most…”
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Real-world efficacy of anti-IL-5 treatment in patients with allergic bronchopulmonary aspergillosis by Tomomatsu, Katsuyoshi, Yasuba, Hirotaka, Ishiguro, Takashi, Imokawa, Shiro, Hara, Johsuke, Soeda, Seiko, Harada, Norihiro, Tsurikisawa, Naomi, Oda, Naohiro, Katoh, Shigeki, Numata, Takanori, Sugino, Yasuteru, Yamada, Mitsuhiro, Kamimura, Mitsuhiro, Terashima, Takeshi, Okada, Naoki, Tanaka, Jun, Oguma, Tsuyoshi, Asano, Koichiro

“…Despite standard treatment with systemic corticosteroids and/or antifungal triazoles, a substantial proportion of patients with allergic bronchopulmonary…”
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Effect of nasally exhaling budesonide/formoterol dry powder inhaled at "fast" inspiratory flow on eosinophilic chronic rhinosinusitis by Hamada, Satoshi, Hira, Daiki, Kobayashi, Yoshiki, Yasuba, Hirotaka

“…Budesonide (BUD)/formoterol (FM) dry powder inhaler has a feature that the fine particle fraction output is dependent on users' inspiratory flow rate. The aim…”
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HFA-BDP Metered-Dose Inhaler Exhaled Through the Nose Improves Eosinophilic Chronic Rhinosinusitis With Bronchial Asthma: A Blinded, Placebo-Controlled Study by Kobayashi, Yoshiki, Yasuba, Hirotaka, Asako, Mikiya, Yamamoto, Takahisa, Takano, Hiroshi, Tomoda, Koichi, Kanda, Akira, Iwai, Hiroshi

“…Eosinophilic chronic rhinosinusitis (ECRS) is a subtype of chronic rhinosinusitis with nasal polyps in Japanese. ECRS highly associated with asthma is a…”
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Radiographic Evidence of Sinonasal Inflammation in Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome: An Underrecognized Association by Hamada, Satoshi, MD, PhD, Tatsumi, Shuji, MD, Kobayashi, Yoshiki, MD, PhD, Matsumoto, Hisako, MD, PhD, Yasuba, Hirotaka, MD, PhD

“…Background Sinonasal inflammation on both clinical examinations and imaging significantly impacts both asthma and chronic obstructive pulmonary disease (COPD)…”
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Cycling therapy with benralizumab and dupilumab for severe eosinophilic asthma with eosinophilic chronic rhinosinusitis and eosinophilic otitis media by Satoshi Hamadaa, Eriko Oginob, Hirotaka Yasubac, d

“…Dear Editor, Eosinophilic inflammation plays a crucial role in the development of not only severe asthma but also eosinophilic chronic rhinosinusitis (ECRS) or…”
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Problems of elderly patients on inhalation therapy: Difference in problem recognition between patients and medical professionals by Hira, Daiki, Komase, Yuko, Koshiyama, Setsuko, Oguma, Tetsuya, Hiramatsu, Tetsuo, Shiraki, Akira, Nishikawa, Masanori, Nakanishi, Masanori, Tsuji, Takao, Matsumoto, Hisako, Ichimura, Koichi, Iwanaga, Takashi, Morikawa, Miwa, Yasuba, Hirotaka, Sugaya, Fumiko, Arakawa, Yukako, Kobayashi, Yoshiki, Kato, Toshiyuki, Futamura, Yutaka, Tsuji, Fumio, Terada, Tomohiro

“…There is no systematic analysis to identify problems involved with instruction on inhalation therapy for elderly patients. We conducted a nationwide…”
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Nasal exhalation of inhaled beclomethasone hydrofluoroalkane-134a to treat chronic rhinosinusitis by Hamada, Satoshi, MD, Matsumoto, Hisako, MD, PhD, Kobayashi, Yoshiki, MD, PhD, Asako, Mikiya, MD, PhD, Yasuba, Hirotaka, MD, PhD

“…Sinus computed tomography (CT) revealed mucosal thickening and opacification of the ethmoid sinuses, olfactory clefts, and maxillary sinuses bilaterally…”
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Clinical option of omalizumab on refractory vasospastic angina with asthma and eosinophilic chronic rhinosinusitis by Hamada, Satoshi, MD, Tatsumi, Shuji, MD, Taniguchi, Tomohiko, MD, Yasuba, Hirotaka, MD, PhD

“…Because she was unwilling to use oral corticosteroids, she was treated with omalizumab (Xolair; Genentech, San Francisco, Calif) 300 mg once a month without…”
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Super-responder and clinical remission in patients with asthma on treatment with single biologic therapy or cycling therapy using dupilumab in a real-world setting by Hamada, Satoshi, Ogino, Eriko, Yasuba, Hirotaka

“…Regarding the therapeutic target in asthma, super-responder status (SR) is a status without systemic corticosteroids. Recently, clinical remission (CR), being…”
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Correlation between rheumatoid factor and peripheral eosinophil count in chronic eosinophilic pneumonia by KUDOU, Megumi, YASUBA, Hirotaka, KOBAYASHI, Yoshiki, HAMADA, Kazuyuki, KITA, Hideo

“…:  The relationship between the blood level of rheumatoid factor (RF) and the peripheral blood eosinophil (Eo) count (white blood cells × %Eo, Eo count) in a…”
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Favorable clinical course after discontinuation of omalizumab treatment in patients with allergic severe asthma: A real-world clinical practice by Hamada, Satoshi, Ogino, Eriko, Yasuba, Hirotaka

“…The success rate of omalizumab discontinuation is 50–75.5%. However, such data are scarce in Japan. We retrospectively investigated the clinical progression…”
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Characteristics of Late-onset Asthma in Elderly Asthmatic Patients by Yasuba, Hirotaka, Kobayashi, Yoshiki, Kudou, Megumi, Hamada, Kazuyuki, Kita, Hideo

“…We evaluated the characteristics of late-onset asthma in elderly patients with asthma, particularly concerning the relationship of IgE mediation and response…”
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Critical role of CCL4 in eosinophil recruitment into the airway by Kobayashi, Yoshiki, Konno, Yasunori, Kanda, Akira, Yamada, Yoshiyuki, Yasuba, Hirotaka, Sakata, Yoshiko, Fukuchi, Mineyo, Tomoda, Koichi, Iwai, Hiroshi, Ueki, Shigeharu

“…Summary Background Excessive eosinophil airway infiltration is a clinically critical condition in some cases. Eosinophilic pneumonia (EP) is a pulmonary…”
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Elevation of the plasma level of RANTES during asthma attacks by Chihara, Junichi, Yasuba, Hirotaka, Tsuda, Akira, Urayama, Osamu, Saito, Norihiro, Honda, Kohei, Kayaba, Hiroyuki, Yamashita, Tetsuji, Kurimoto, Fumihiko, Yamada, Hidekazu

“…Background: RANTES is considered to play an important role in various immune and allergic disorders since it is a potent chemoattractant for inflammatory cells…”
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Residual exhaled nitric oxide elevation in asthmatics is associated with eosinophilic chronic rhinosinusitis by Kobayashi, Yoshiki, Asako, Mikiya, Ooka, Hisashi, Kanda, Akira, Tomoda, Koichi, Yasuba, Hirotaka

“…Objective: Eosinophilic chronic rhinosinusitis (ECRS) is as a subgroup of chronic rhinosinusitis (CRS) with nasal polyps. ECRS is a refractory disease closely…”
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Nasal nitric oxide improved by continuous positive airway pressure therapy for upper airway inflammation in obstructive sleep apnea by Hamada, Satoshi, Tatsumi, Shuji, Kobayashi, Yoshiki, Yasuba, Hirotaka

“…Purpose In this report, we examined the association between obstructive sleep apnea (OSA) and upper and lower airway inflammation based on nitric oxide (NO)…”
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Replacement of SFC-DPI with SFC-MDI exhaled through the nose improves eosinophilic chronic rhinosinusitis in patients with bronchial asthma by Kobayashi, Yoshiki, Asako, Mikiya, Yamamoto, Takahisa, Yasuba, Hirotaka, Tomoda, Koichi, Kanda, Akira

“…Eosinophilic chronic rhinosinusitis (ECRS), a subgroup of chronic rhinosinusitis with nasal polyps, is a refractory disease closely associated with bronchial…”
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Serum rheumatoid factor and peripheral blood eosinophil counts in patients with bronchial asthma by Kobayashi, Yoshiki, Yasuba, Hirotaka, Kita, Hideo, Hamada, Kazuyuki, Chihara, Junichi

“…These days some reports say that bronchial asthma, especially severe asthma, is systemic inflammatory and its severity correlates with eosinophil counts. Some…”
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