Search Results - "Yasuaki, Sagara"

Artificial intelligence for breast cancer detection in mammography: experience of use of the ScreenPoint Medical Transpara system in 310 Japanese women by Sasaki, Michiro, Tozaki, Mitsuhiro, Rodríguez-Ruiz, Alejandro, Yotsumoto, Daisuke, Ichiki, Yumi, Terawaki, Aiko, Oosako, Shunichi, Sagara, Yasuaki, Sagara, Yoshiaki

“…Background To compare the breast cancer detection performance in digital mammograms of a panel of three unaided human readers (HR) versus a stand-alone…”
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Diffuse distribution of tumor-infiltrating lymphocytes is a marker for better prognosis and chemotherapeutic effect in triple-negative breast cancer by Hida, Akira I., Watanabe, Takahiro, Sagara, Yasuaki, Kashiwaba, Masahiro, Sagara, Yoshiaki, Aogi, Kenjiro, Ohi, Yasuyo, Tanimoto, Akihide

“…Purpose High-density tumor-infiltrating lymphocytes (TILs) are a prognostic marker for triple-negative breast cancer (TNBC). However, lymphocytic infiltration…”
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The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2018 edition by Shimoi, Tatsunori, Nagai, Shigenori E., Yoshinami, Tetsuhiro, Takahashi, Masato, Arioka, Hitoshi, Ishihara, Mikiya, Kikawa, Yuichiro, Koizumi, Kei, Kondo, Naoto, Sagara, Yasuaki, Takada, Masahiro, Takano, Toshimi, Tsurutani, Junji, Naito, Yoichi, Nakamura, Rikiya, Hattori, Masaya, Hara, Fimikata, Hayashi, Naoki, Mizuno, Toshiro, Miyashita, Minoru, Yamashita, Nami, Yamanaka, Takashi, Saji, Shigehira, Iwata, Hiroji, Toyama, Tatsuya

“…Purpose We present the English version of The Japanese Breast Cancer Society (JBCS) Clinical Practice Guidelines for systemic treatment of breast cancer, 2018…”
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F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner by Yumimoto, Kanae, Akiyoshi, Sayuri, Ueo, Hiroki, Sagara, Yasuaki, Onoyama, Ichiro, Ueo, Hiroaki, Ohno, Shinji, Mori, Masaki, Mimori, Koshi, Nakayama, Keiichi I

“…The gene encoding F-box protein FBXW7 is frequently mutated in many human cancers. Although most previous studies have focused on the tumor-suppressive…”
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Neoadjuvant anastrozole versus tamoxifen in patients receiving goserelin for premenopausal breast cancer (STAGE): a double-blind, randomised phase 3 trial by Masuda, Norikazu, MD, Sagara, Yasuaki, MD, Kinoshita, Takayuki, MD, Iwata, Hiroji, MD, Nakamura, Seigo, Prof, Yanagita, Yasuhiro, MD, Nishimura, Reiki, MD, Iwase, Hirotaka, Prof, Kamigaki, Shunji, MD, Takei, Hiroyuki, MD, Noguchi, Shinzaburo, Prof

“…Summary Background Aromatase inhibitors have shown increased efficacy compared with tamoxifen in postmenopausal early breast cancer. We aimed to assess the…”
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Paradigm Shift toward Reducing Overtreatment of Ductal Carcinoma In Situ of Breast by Sagara, Yasuaki, Julia, Wong, Golshan, Mehra, Toi, Masakazu

“…The prevalence of ductal carcinoma (DCIS) of the breast has increased substantially after the introduction of breast cancer screening programs, although the…”
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Breast cancer survival among Japanese individuals and US residents of Japanese and other origins: a comparative registry-based study by Ogiya, Rin, Niikura, Naoki, Kumamaru, Hiraku, Takeuchi, Yoshinori, Okamura, Takuho, Kinoshita, Takayuki, Aogi, Kenjiro, Anan, Keisei, Iijima, Kotaro, Ishida, Takanori, Iwamoto, Takayuki, Kawai, Masaaki, Kojima, Yasuyuki, Sakatani, Takashi, Sagara, Yasuaki, Hayashi, Naoki, Masuoka, Hideji, Yoshida, Masayuki, Miyata, Hiroaki, Tsuda, Hitoshi, Imoto, Shigeru, Jinno, Hiromitsu

“…Background Breast cancer survival outcomes vary across different ethnic groups. We clarified the differences in clinicopathological and survival…”
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Circulating microRNA Panel as a Potential Novel Biomarker for Oral Squamous Cell Carcinoma Diagnosis by Nakamura, Kodai, Hiyake, Naomi, Hamada, Tomofumi, Yokoyama, Seiya, Mori, Kazuki, Yamashiro, Kouta, Beppu, Mahiro, Sagara, Yasuaki, Sagara, Yoshiaki, Sugiura, Tsuyoshi

“…A lack of reliable biomarkers for oral squamous cell carcinoma (OSCC) poses a major clinical issue. The sensitivity and specificity of classical serum tumor…”
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Satisfaction of Patients Who Received Breast-Conserving Surgery Using the Suture Scaffold Technique: A Single-Institution, Cross-Sectional Study by Mitsueda, Reiko, Gen, Anri, Fujiki, Yoshitaka, Gondo, Naomi, Sato, Mutsumi, Kawano, Junko, Kuninaka, Koichi, Kanemitsu, Shuichi, Teraoka, Megumi, Matsuyama, Yoshito, Baba, Shinichi, Nomoto, Sugako, Sloan, Robert, Rai, Yoshiaki, Sagara, Yoshiaki, Sagara, Yasuaki

“…Background Optimal cosmetic results after breast-conserving surgery (BCS) improve patient satisfaction. The suture scaffold technique (SST) is a breast…”
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Clinicopathological predictors of postoperative upstaging to invasive ductal carcinoma (IDC) in patients preoperatively diagnosed with ductal carcinoma in situ (DCIS): a multi-institutional retrospective cohort study by Tanaka, Kiyo, Masuda, Norikazu, Hayashi, Naoki, Sagara, Yasuaki, Hara, Fumikata, Kadoya, Takayuki, Matsui, Akira, Miyazaki, Chieko, Shien, Tadahiko, Tokunaga, Eriko, Hayashi, Takako, Niikura, Naoki, Maeda, Shigeto, Komoike, Yoshihumi, Bando, Hiroko, Kanbayashi, Chizuko, Iwata, Hiroji

“…Background We conducted a prospective study with the intention to omit surgery for patients with ductal carcinoma in situ (DCIS) of the breast. We aimed to…”
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Significance of glucocorticoid signaling in triple-negative breast cancer patients: a newly revealed interaction with androgen signaling by Kanai, Ayako, McNamara, Keely May, Iwabuchi, Erina, Miki, Yasuhiro, Onodera, Yoshiaki, Guestini, Fouzia, Khalid, Freeha, Sagara, Yasuaki, Ohi, Yasuyo, Rai, Yoshiaki, Yamaguchi, Rin, Tanaka, Maki, Miyashita, Minoru, Ishida, Takanori, Sasano, Hironobu

“…Purpose Chemotherapy is the only current effective systemic treatment for triple-negative breast cancer (TNBC) patients. Therefore, the identification of…”
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Efficacy of probiotics and trimebutine maleate for abemaciclib-induced diarrhea: A randomized, open-label phase II trial (MERMAID, WJOG11318B) by Masuda, Hiroko, Tanabe, Yuko, Sakai, Hitomi, Matsumoto, Koji, Shimomura, Akihiko, Doi, Mihoko, Miyoshi, Yasuo, Takahashi, Masato, Sagara, Yasuaki, Tokunaga, Shinya, Iwasa, Tsutomu, Niikura, Naoki, Yoshimura, Kenichi, Takano, Toshimi, Tsurutani, Junji

“…Abemaciclib-induced diarrhea (AID) impairs quality of life (QOL) and treatment adherence in patients with breast cancer. Supportive treatment with loperamide…”
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Ki-67 response-guided preoperative chemotherapy for HER2-positive breast cancer: results of a randomised Phase 2 study by Mukai, Hirofumi, Yamaguchi, Takeshi, Takahashi, Masato, Hozumi, Yasuo, Fujisawa, Tomomi, Ohsumi, Shozo, Akabane, Hiromitsu, Nishimura, Reiki, Takashima, Tsutomu, Park, Youngjin, Sagara, Yasuaki, Toyama, Tatsuya, Imoto, Shigeru, Mizuno, Toshiro, Yamashita, Satoshi, Fujii, Satoshi, Uemura, Yukari

“…Background The effectiveness of a therapeutic strategy that switches chemotherapy, based on Ki-67 tumour expression after initial therapy, relative to that of…”
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ASO Author Reflections: Patients’ Satisfaction After Breast Conserving Surgery Using the Suture Scaffold Technique by Mitsueda, Reiko, Gen, Anri, Fujiki, Yoshitaka, Gondo, Naomi, Sato, Mutsumi, Kawano, Junko, Kuninaka, Kouichi, Kanemitsu, Shuichi, Teraoka, Megumi, Matsuyama, Yoshito, Baba, Shinichi, Nomoto, Sugako, Sloan, Robert, Rai, Yoshiaki, Sagara, Yoshiaki, Sagara, Yasuaki

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ASO Visual Abstract: Satisfaction of Patients Who Received Breast-Conserving Surgery Using the Suture Scaffold Technique: A Single-Institution, Cross-Sectional Study by Mitsueda, Reiko, Gen, Anri, Fujiki, Yoshitaka, Gondo, Naomi, Sato, Mutsumi, Kawano, Junko, Kuninaka, Koichi, Kanemitsu, Shuichi, Teraoka, Megumi, Matsuyama, Yoshito, Baba, Shinichi, Nomoto, Sugako, Sloan, Robert, Rai, Yoshiaki, Sagara, Yoshiaki, Sagara, Yasuaki

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Abstract P2-03-02: Clinical utility of bone scan index (BSI) for breast cancer patients with bone metastasis -Multi-institutional prospective cohort study by Kondo, Naoto, Naito, Yoichi, Yokota, Isao Yokota, Nakamura, Rikiya, Kikawa, Yuichiro, Maeda, Hideki, Akabane, Hiromitsu Akabane, Sagara, Yasuaki Sagara, Aihara, Tomohiko, Takahashi, Mina, Ohtani, Yoko, Ohtani, Shoichiro, Mukai, Hirofumi

“…Abstract Background: The bone is the most frequent site of metastasis from breast cancer. However, evaluation for the response to systemic therapy in bone…”
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Radiotherapy versus low-dose tamoxifen following breast-conserving surgery for low-risk and estrogen receptor-positive breast ductal carcinoma in situ: an international open-label randomized non-inferiority trial (TBCC-ARO DCIS Trial) by Kuo, Sung-Hsin, Tseng, Ling-Ming, Chen, Shou-Tung, Sagara, Yasuaki, Chang, Yuan-Ching, Yeh, Hsien-Tang, Kuo, Yao-Lung, Hung, Chih-Chiang, Lu, Tzu-Pin, Lee, Yi-Hsuan, Toi, Masakazu, Huang, Chiun-Sheng

“…Abstract Background Radiotherapy (RT) following breast-conserving surgery (BCS) is mainly used to decrease the rate of ipsilateral breast tumor recurrence…”
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Interleukin (IL)-17A in triple-negative breast cancer: a potent prognostic factor associated with intratumoral neutrophil infiltration by Khalid, Freeha, Takagi, Kiyoshi, Sato, Ai, Yamaguchi, Mio, Guestini, Fouzia, Miki, Yasuhiro, Miyashita, Minoru, Hirakawa, Hisashi, Ohi, Yasuyo, Rai, Yoshiaki, Sagara, Yasuaki, Sasano, Hironobu, Suzuki, Takashi

“…Background Triple-negative breast cancer (TNBC) is characterized as highly immunogenic and lacks specific targeted therapies. Interleukin 17A (IL-17A) is a…”
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Factors associated with financial toxicity in patients with breast cancer in Japan: a comparison of patient and physician perspectives by Saeki, Sumito, Iwatani, Tsuguo, Kitano, Atsuko, Sakurai, Naomi, Tanabe, Yuko, Yamauchi, Chikako, Igarashi, Ataru, Kajimoto, Yusuke, Kuba, Sayaka, Hara, Fumikata, Sagara, Yasuaki, Ohno, Shinji

“…Background Financial toxicity (FT) is a notable concern for patients with breast cancer worldwide. The situation regarding FT in Japan, however, has not been…”
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Significant Effect of Polymorphisms in CYP2D6 on Response to Tamoxifen Therapy for Breast Cancer: A Prospective Multicenter Study by Zembutsu, Hitoshi, Nakamura, Seigo, Akashi-Tanaka, Sadako, Kuwayama, Takashi, Watanabe, Chie, Takamaru, Tomoko, Takei, Hiroyuki, Ishikawa, Takashi, Miyahara, Kana, Matsumoto, Hiroshi, Hasegawa, Yoshie, Kutomi, Goro, Shima, Hiroaki, Satomi, Fukino, Okazaki, Minoru, Zaha, Hisamitsu, Onomura, Mai, Matsukata, Ayami, Sagara, Yasuaki, Baba, Shinichi, Yamada, Akimitsu, Shimada, Kazuhiro, Shimizu, Daisuke, Tsugawa, Koichiro, Shimo, Arata, Tan, Ern Yu, Hartman, Mikael, Chan, Ching-Wan, Lee, Soo Chin, Nakamura, Yusuke

“…CYP2D6 is the key enzyme responsible for the generation of the potent active metabolite of tamoxifen, "endoxifen." There are still controversial reports…”
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