Search Results - "Yasoda, A."
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Circulatory CNP Rescues Craniofacial Hypoplasia in Achondroplasia
Published in Journal of dental research (01-12-2017)“…Achondroplasia is the most common genetic form of human dwarfism, characterized by midfacial hypoplasia resulting in occlusal abnormality and foramen magnum…”
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The Effects of C-type Natriuretic Peptide on Craniofacial Skeletogenesis
Published in Journal of dental research (01-01-2013)“…C-type natriuretic peptide (CNP) is a potent stimulator of long bone and vertebral development via endochondral ossification. In the present study, we…”
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Adiposity induced by interleukin-17A blockade
Published in Diabetes & metabolism (01-02-2017)Get full text
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Complementary antagonistic actions between C-type natriuretic peptide and the MAPK pathway through FGFR-3 in ATDC5 cells
Published in Bone (New York, N.Y.) (01-06-2005)“…We previously reported that C-type natriuretic peptide (CNP) stimulates endochondral ossification and corrects the reduction in body length of achondroplasia…”
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C-Type natriuretic peptide/guanylate cyclase B system in rat osteogenic ROB-C26 cells and its down-regulation by dexamethazone
Published in Calcified tissue international (01-12-1999)“…There is recent evidence that natriuretic peptides are important regulators of bone and cartilage, although they were originally identified as the cardiac…”
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Genetic Models Reveal That Brain Natriuretic Peptide Can Signal through Different Tissue-Specific Receptor-Mediated Pathways
Published in Endocrinology (Philadelphia) (01-10-2000)“…Abstract Brain natriuretic peptide (BNP), a hormone produced primarily by the cardiac ventricle, is thought to be involved in a variety of homeostatic…”
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Prostaglandin E2 (PGE2) autoamplifies its production through EP1 subtype of PGE receptor in mouse osteoblastic MC3T3-E1 cells
Published in Calcified tissue international (01-04-1998)“…Prostaglandin E2 (PGE2) is known to autoamplify its production in the osteoblasts through the induction of prostaglandin G/H synthase-2 (PGHS-2), which is the…”
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Prostaglandin E2 (PGE2) Induces the c-fos and c-jun Expressions via the EP1 Subtype of PGE Receptor in Mouse Osteoblastic MC3T3-E1 Cells
Published in Calcified tissue international (01-03-2000)“…This study examined which subtype(s) of PGE receptors is involved in the induction of c-fos and c-jun by PGE^sub 2^ in MC3T3-E1 cells. We also investigated the…”
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7211 Clinical and Molecular Characterization Of An Aldosterone-Producing Adenoma Harboring Double Somatic Mutations In CTNNB1 and GNA11
Published in Journal of the Endocrine Society (05-10-2024)“…Abstract Disclosure: A. Blinder: None. K. Nanba: Grant Recipient; Self; AstraZeneca. A. Udager: None. Y. Hirokawa: None. T. Miura: None. H. Okuno: None. K…”
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Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway
Published in Nature medicine (01-01-2004)“…Achondroplasia is the most common genetic form of human dwarfism, for which there is presently no effective therapy. C-type natriuretic peptide (CNP) is a…”
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Prostaglandin E 2 (PGE 2 ) Autoamplifies its Production Through EP 1 Subtype of PGE Receptor in Mouse Osteoblastic MC3T3-E1 Cells
Published in Calcified tissue international (01-04-1998)Get full text
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Dwarfism and Early Death in Mice Lacking C-Type Natriuretic Peptide
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2001)“…Longitudinal bone growth is determined by endochondral ossification that occurs as chondrocytes in the cartilaginous growth plate undergo proliferation,…”
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High-dose glucocorticoid treatment induces rapid loss of trabecular bone mineral density and lean body mass
Published in Osteoporosis international (01-01-2006)“…A recent large-scale study revealed that glucocorticoid treatment increased fracture risk, which occurred at a far smaller dose and by a shorter duration than…”
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Cyclic GMP-Dependent Protein Kinase II Plays a Critical Role in C-Type Natriuretic Peptide-Mediated Endochondral Ossification
Published in Endocrinology (Philadelphia) (01-09-2002)“…Longitudinal bone growth is determined by endochondral ossification at the growth plate, which is located at both ends of long bones and vertebrae, and…”
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Hypomorphic mutation in mouse Nppc gene causes retarded bone growth due to impaired endochondral ossification
Published in Biochemical and biophysical research communications (07-11-2008)“…Long bone abnormality (lbab/lbab) is a spontaneous mutant mouse characterized by dwarfism with shorter long bones. A missense mutation was reported in the Nppc…”
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Natriuretic peptide regulation of endochondral ossification. Evidence for possible roles of the C-type natriuretic peptide/guanylyl cyclase-B pathway
Published in The Journal of biological chemistry (08-05-1998)“…The natriuretic peptide family consists of three structurally related endogenous ligands: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP),…”
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Abstracts at the 37th Kansai Calcium Conference October 19, 1996 Osaka Obayashi Building, Osaka, Japan
Published in Journal of bone and mineral metabolism (01-09-1997)Get full text
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Thyroid Hormones Promote Chondrocyte Differentiation in Mouse ATDC5 Cells and Stimulate Endochondral Ossification in Fetal Mouse Tibias Through Iodothyronine Deiodinases in the Growth Plate
Published in Journal of bone and mineral research (01-03-2002)“…Thyroid hormones (THs), 3,3′,5‐triiodo‐L‐thyronine (T3) and L‐thyroxine (T4), are important for the normal development of the growth plate (GP); congenital TH…”
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Crucial Involvement of the EP4 Subtype of Prostaglandin E Receptor in Osteoclast Formation by Proinflammatory Cytokines and Lipopolysaccharide
Published in Journal of bone and mineral research (01-02-2000)“…Prostaglandin E2 (PGE2) exerts its effects through the PGE receptor that consists of four subtypes (EP1, EP2, EP3, and EP4). Osteoclast formation in the…”
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