Search Results - "Yashin, Anatoly I."

Time trends of incidence of age-associated diseases in the US elderly population: Medicare-based analysis by Akushevich, Igor, Kravchenko, Julia, Ukraintseva, Svetlana, Arbeev, Konstantin, Yashin, Anatoly I

“…time trends of age-adjusted incidence rates of 19 ageing-related diseases were evaluated for 1992-2005 period with the National Long Term Care Survey and the…”
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Cancer in rodents: does it tell us about cancer in humans? by Anisimov, Vladimir N, Ukraintseva, Svetlana V, Yashin, Anatoly I

“…Information obtained from animal models (mostly mice and rats) has contributed substantially to the development of treatments for human cancers. However,…”
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New stochastic carcinogenesis model with covariates: An approach involving intracellular barrier mechanisms by Akushevich, Igor, Veremeyeva, Galina, Kravchenko, Julia, Ukraintseva, Svetlana, Arbeev, Konstantin, Akleyev, Alexander V., Yashin, Anatoly I.

“…► New cancer model connects age-specific hazard rates with intracellular processes. ► New multiple-pathway model of carcinogenesis is based on lab…”
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Joint Analysis of Health Histories, Physiological State, and Survival by YASHIN, ANATOLY I., AKUSHEVICH, IGOR, ARBEEV, KONSTANTIN G., KULMINSKI, ALEXANDER, UKRAINTSEVA, SVETLANA

“…Data on individual health histories, age trajectories of physiological or biological variables, and mortality allow for the study of the joint evolution of…”
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Effect of exposure to light‐at‐night on life span and spontaneous carcinogenesis in female CBA mice by Anisimov, Vladimir N., Baturin, Dmitri A., Popovich, Irina G., Zabezhinski, Mark A., Manton, Kenneth G., Semenchenko, Anna V., Yashin, Anatoly I.

“…The effect of constant illumination on the development of spontaneous tumors in female CBA mice was investigated. Fifty female CBA mice starting from the age…”
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The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER‐2/neu transgenic mice by Anisimov, Vladimir N., Alimova, Irina N., Baturin, Dmitri A., Popovich, Irina G., Zabezhinski, Mark A., Manton, Kenneth G., Semenchenko, Anna V., Yashin, Anatoly I.

“…The effect of various regimens of treatment with melatonin on the development of mammary tumors in HER2/neu transgenic mice was investigated. Female HER‐2/neu…”
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Decrease in the lgl tumor suppressor dose in Drosophila increases survival and longevity in stress conditions by Golubovsky, Mikhail D., Weisman, Nataly Y., Arbeev, Konstantin G., Ukraintseva, Svetlana V., Yashin, Anatoly I.

“…Recent studies suggest that downregulation of tumor suppressor genes might not only favor cancer development but also postpone organisms’ aging and increase…”
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MODELING DETERMINISTIC EFFECTS IN HEMATOPOIETIC SYSTEM CAUSED BY CHRONIC EXPOSURE TO IONIZING RADIATION IN LARGE HUMAN COHORTS by Akushevich, Igor V, Veremeyeva, Galina A, Dimov, Georgy P, Ukraintseva, Svetlana V, Arbeev, Konstantin G, Akleyev, Alexander V, Yashin, Anatoly I

“…A new model of the hematopoietic system for humans chronically exposed to ionizing radiation allows for quantitative description of the initial hematopoiesis…”
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Modeling hematopoietic system response caused by chronic exposure to ionizing radiation by Akushevich, Igor V., Veremeyeva, Galina A., Dimov, Georgy P., Ukraintseva, Svetlana V., Arbeev, Konstantin G., Akleyev, Alexander V., Yashin, Anatoly I.

“…A new model of the hematopoietic system response in humans chronically exposed to ionizing radiation describes the dynamics of the hematopoietic stem cell…”
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Early hematopoiesis inhibition under chronic radiation exposure in humans by Akleyev, Alexander V, Akushevich, Igor V, Dimov, Georgy P, Veremeyeva, Galina A, Varfolomeyeva, Tatyana A, Ukraintseva, Svetlana V, Yashin, Anatoly I

“…The major goal of this study was to identify and quantitatively describe the association between the characteristics of chronic (low-dose rate) exposure to…”
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EARLY HEMATOPOIETIC EFFECTS OF CHRONIC RADIATION EXPOSURE IN HUMANS by Akleyev, Alexander V, Akushevich, Igor V, Dimov, Georgy P, Veremeyeva, Galina A, Varfolomeyeva, Tatyana A, Ukraintseva, Svetlana V, Yashin, Anatoly I

“…The major goal of this study is to investigate and quantitatively describe the nature of the relationship between the characteristics of chronic exposure to…”
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Opposite Phenotypes of Cancer and Aging Arise from Alternative Regulation of Common Signaling Pathways by UKRAINTSEVA, SVETLANA V., YASHIN, ANATOLY I.

“…: Phenotypic features of malignant and senescent cells are in many instances opposite. Cancer cells do not “age”; their metabolic, proliferative, and growth…”
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Insulin in aging and cancer: antidiabetic drug diabenol as geroprotector and anticarcinogen by Popovich, Irina G., Zabezhinski, Mark A., Egormin, Peter A., Tyndyk, Margarita L., Anikin, Ivan V., Spasov, Alexander A., Semenchenko, Anna V., Yashin, Anatoly I., Anisimov, Vladimir N.

“…The effects of new antidiabetic drug Diabenol ® (9-β-diethylaminoethyl-2,3-dihydroimidazo-(1,2-α)benzimidazol dihydrochloride) on life span and spontaneous…”
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Antiaging Treatments Have Been Legally Prescribed for Approximately Thirty Years by UKRAINTSEVA, SVETLANA V., ARBEEV, KONSTANTIN G., MICHALSKY, ANATOLY I., YASHIN, ANATOLY I.

“…: There is an interesting divergence between the achievements of geriatrics and gerontology. On the one hand, during the last 30 years physicians in many…”
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Modeling hematopoietic system response caused by chronic exposure to ionizing radiation by Akushevich, Igor V., Veremeyeva, Galina A., Dimov, Georgy P., Ukraintseva, Svetlana V., Arbeev, Konstantin G., Akleyev, Alexander V., Yashin, Anatoly I.

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Treating cancer with embryonic stem cells: rationale comes from aging studies by Ukraintseva, Svetlana V, Yashin, Anatoly I

“…In an earlier poster paper (1) we proposed that cancer can be viewed not only as a fatal disease but also as a local aberrant, rejuvenation, in an organism,…”
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Cancer as "Rejuvenescence" by UKRAINTSEVA, SVETLANA V., YASHINA, ANATOLY I.

“…: Comparative analysis of malignant and senescent cells shows that their phenotypic features are in many instances contrary. Cancer cells do not “age”; their…”
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Individual Aging and Cancer Risk: How Are They Related? by Ukraintseva, Svetlana V., Yashin, Anatoli I.

“…When individuals get older, the risk of many chronic diseases increases. This increase is in agreement with common theories of aging, such as mutation…”
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MODELING DETERMINISTIC EFFECTS IN HEMATOPOIETIC SYSTEM CAUSED BY CHRONIC EXPOSURE TO IONIZING RADIATION IN LARGE HUMAN COHORTS by Akushevich, Igor V., Veremeyeva, Galina A., Dimov, Georgy P., Ukraintseva, Svetlana V., Arbeev, Konstantin G., Akleyev, Alexander V., Yashin, Anatoly I.

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Effect of exposure to light-at-night on life span and spontaneous carcinogenesis in female CBA mice by ANISIMOV, Vladimir N, BATURIN, Dmitri A, POPOVICH, Irina G, ZABEZHINSKI, Mark A, MANTON, Kenneth G, SEMENCHENKO, Anna V, YASHIN, Anatoly I

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