Search Results - "Yasha, Kresh"
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Reprogramming cardiomyocyte mechanosensing by crosstalk between integrins and hyaluronic acid receptors
Published in Journal of biomechanics (15-03-2012)“…Abstract The elastic modulus of bioengineered materials has a strong influence on the phenotype of many cells including cardiomyocytes. On polyacrylamide (PAA)…”
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Cardiac myocyte remodeling mediated by N-cadherin-dependent mechanosensing
Published in American journal of physiology. Heart and circulatory physiology (01-04-2011)“…Cell-to-cell adhesions are crucial in maintaining the structural and functional integrity of cardiac cells. Little is known about the mechanosensitivity and…”
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Biologically-Inspired Spiral Flow Generation for Mechanically Assisted Circulation
Published in The Journal of heart and lung transplantation (01-04-2017)Get full text
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Cardiomyocyte-mediated contact programs human mesenchymal stem cells to express cardiogenic phenotype
Published in The Journal of thoracic and cardiovascular surgery (01-07-2003)“…Intercellular crosstalk and cellular plasticity are key factors in embryogenesis and organogenesis. The microenvironment plays a critical role in directing the…”
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Left ventricular volume regulation in heart failure with preserved ejection fraction
Published in Physiological reports (01-07-2013)“…Ejection Fraction (EF) has attained the recognition as indicator of global ventricular performance. Remarkably, precise historical origins promoting the…”
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Using Heart Rate Variability to Stratify Risk of Obstetric Patients Undergoing Spinal Anesthesia
Published in Anesthesia and analgesia (01-12-2004)“…In this study, we evaluated whether point correlation dimension (PD2), a measure of heart rate variability, can predict hypotension accompanying spinal…”
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α-Catenin localization and sarcomere self-organization on N-cadherin adhesive patterns are myocyte contractility driven
Published in PloS one (15-10-2012)“…The N-cadherin (N-cad) complex plays a crucial role in cardiac cell structure and function. Cadherins are adhesion proteins linking adjacent cardiac cells and,…”
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A Novel Technique for Experimental Flow Visualization of Mechanical Valves
Published in ASAIO journal (1992) (01-03-2016)“…The geometry of the hinge region in mechanical heart valves has been postulated to play an important role in the development of thromboembolic events (TEs)…”
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A Novel Triblock Copolymer Hydrogel Foam Delivery System to Improve Talc Pleurodesis Efficacy
Published in Journal of the American College of Surgeons (01-10-2017)Get full text
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Aortic Hemodynamics of Spiral-Flow-Generated Mechanical Assistance
Published in The Annals of thoracic surgery (01-05-2020)“…Mechanical circulatory support devices are being increasingly used as destination therapy in end-stage heart failure patients. Although current devices have…”
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Intercellular and extracellular mechanotransduction in cardiac myocytes
Published in Pflügers Archiv (01-07-2011)“…Adult cardiomyocytes are terminally differentiated with minimal replicative capacity. Therefore, long-term preservation or enhancement of cardiac function…”
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Left ventricular volume regulation in heart failure with preserved ejection fraction
Published in Physiological reports (01-09-2013)Get full text
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Comparison of eight prosthetic aortic valves in a cadaver model
Published in The Journal of thoracic and cardiovascular surgery (01-12-2007)“…Objectives Proper valve selection is critical to ensure appropriate valve replacement for patients, because implantation of a small valve might place the…”
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Circulatory Mechanotherapeutics: Moving with the Force
Published in Current cardiology reports (01-10-2018)“…Purpose of Review This review describes the current state of advancements in mechanical circulatory support (MCS) devices with significantly improved…”
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Dual Defibrillation is Highly Variable: An Analysis of Pulse Interval Delivered in Dual Defibrillation
Published in Prehospital emergency care (03-03-2020)“…Background: Dual defibrillation (DD) is a technique where two external defibrillators are applied with two different pad configurations and discharged to treat…”
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Augmentation of integrin-mediated mechanotransduction by hyaluronic acid
Published in Biomaterials (01-01-2014)“…Abstract Changes in tissue and organ stiffness occur during development and are frequently symptoms of disease. Many cell types respond to the stiffness of…”
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The mechanics of spiral flow: Enhanced washout and transport
Published in Artificial organs (01-12-2019)“…Spiral/helical forms of blood flow have been observed in large arteries of the cardiovascular system, but their benefits remain underappreciated. Spiral flow…”
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Mechanically Stimulated Contraction of Engineered Cardiac Constructs Using a Microcantilever
Published in IEEE transactions on biomedical engineering (01-02-2015)“…The beating heart undergoes cyclic mechanical and electrical activity during systole and diastole. The interaction between mechanical stimulation and…”
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Ultrasound-induced modulation of cardiac rhythm in neonatal rat ventricular cardiomyocytes
Published in Journal of applied physiology (1985) (01-06-2015)“…Isolated neonatal rat ventricular cardiomyocytes were used to study the influence of ultrasound on the chronotropic response in a tissue culture model. The…”
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