Search Results - "Yaseen, Adam B."

LPA disruption with AAV-CRISPR potently lowers plasma apo(a) in transgenic mouse model: A proof-of-concept study by Doerfler, Alexandria M., Park, So Hyun, Assini, Julia M., Youssef, Amer, Saxena, Lavanya, Yaseen, Adam B., De Giorgi, Marco, Chuecos, Marcel, Hurley, Ayrea E., Li, Ang, Marcovina, Santica M., Bao, Gang, Boffa, Michael B., Koschinsky, Marlys L., Lagor, William R.

“…Lipoprotein(a) (Lp(a)) represents a unique subclass of circulating lipoprotein particles and consists of an apolipoprotein(a) (apo(a)) molecule covalently…”
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High levels of lipoprotein(a) in transgenic mice exacerbate atherosclerosis and promote vulnerable plaque features in a sex-specific manner by Assini, Julia M., Clark, Justin R., Youssef, Amer, Xing, Chuce, Doerfler, Alexandria M., Park, So Hyun, Saxena, Lavanya, Yaseen, Adam B., Børen, Jan, Gros, Robert, Bao, Gang, Lagor, William R., Boffa, Michael B., Koschinsky, Marlys L.

“…Despite increased clinical interest in lipoprotein(a) (Lp(a)), many questions remain about the molecular mechanisms by which it contributes to atherosclerotic…”
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