Search Results - "Yarovoi, Serge V."

Atomic description of the immune complex involved in heparin-induced thrombocytopenia by Cai, Zheng, Yarovoi, Serge V., Zhu, Zhiqiang, Rauova, Lubica, Hayes, Vincent, Lebedeva, Tatiana, Liu, Qun, Poncz, Mortimer, Arepally, Gowthami, Cines, Douglas B., Greene, Mark I.

“…Heparin-induced thrombocytopenia (HIT) is an autoimmune thrombotic disorder caused by immune complexes containing platelet factor 4 (PF4), antibodies to PF4…”
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Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes by Khandelwal, Sanjay, Barnes, Ayiesha, Rauova, Lubica, Sarkar, Amrita, Rux, Ann H., Yarovoi, Serge V., Zaitsev, S. Sergei, Lambris, John D., Myoung, Sooho S., Johnson, Alexandra, Lee, Grace M., Duarte, Madelaine, Poncz, Mortimer, Arepally, Gowthami M., Cines, Douglas B.

“…Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder mediated by ultra-large immune complexes (ULICs) containing immunoglobulin G (IgG)…”
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Dynamic antibody-binding properties in the pathogenesis of HIT by Sachais, Bruce S., Litvinov, Rustem I., Yarovoi, Serge V., Rauova, Lubica, Hinds, Jillian L., Rux, Ann H., Arepally, Gowthami M., Poncz, Mortimer, Cuker, Adam, Weisel, John W., Cines, Douglas B.

“…Rapid laboratory assessment of heparin-induced thrombocytopenia (HIT) is important for disease recognition and management. The utility of contemporary…”
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Polyphosphate/platelet factor 4 complexes can mediate heparin-independent platelet activation in heparin-induced thrombocytopenia by Cines, Douglas B., Yarovoi, Serge V., Zaitsev, Sergei V., Lebedeva, Tatiana, Rauova, Lubica, Poncz, Mortimer, Arepally, Gowthami M., Khandelwal, Sanjay, Stepanova, Victoria, Rux, Ann H., Cuker, Adam, Guo, Cecilia, Ocariza, Linnette Mae, Travers, Richard J., Smith, Stephanie A., Kim, Hugh, Morrissey, James H., Conway, Edward M.

“…Heparin-induced thrombocytopenia (HIT) is a thrombotic disorder initiated by antibodies to complexes between platelet factor 4 (PF4) and heparin. The risk of…”
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Modulation of ultralarge immune complexes in heparin–induced thrombocytopenia by Cai, Zheng, Bdeir, Khalil, Yarovoi, Serge V., Rauova, Lubica, Arepally, Gowthami M., Khandelwal, Sanjay, Rollin, Jerome, Gruel, Yves, Zaitsev, Sergei, Poncz, Mortimer, Greene, Mark I., Cines, Douglas B.

“…Heparin–induced thrombocytopenia (HIT) is a serious thrombotic disorder caused by ultralarge immune complexes (ULICs) containing platelet factor 4 (PF4) and…”
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Targeting plasminogen activator inhibitor-1 in tetracycline-induced pleural injury in rabbits by Florova, Galina, Azghani, Ali O, Karandashova, Sophia, Schaefer, Chris, Yarovoi, Serge V, Declerck, Paul J, Cines, Douglas B, Idell, Steven, Komissarov, Andrey A

“…Elevated active plasminogen activator inhibitor-1 (PAI-1) has an adverse effect on the outcomes of intrapleural fibrinolytic therapy (IPFT) in…”
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Novel diagnostic assays for heparin-induced thrombocytopenia by Cuker, Adam, Rux, Ann H., Hinds, Jillian L., Dela Cruz, May, Yarovoi, Serge V., Brown, Isola A.M., Yang, Wei, Konkle, Barbara A., Arepally, Gowthami M., Watson, Stephen P., Cines, Douglas B., Sachais, Bruce S.

“…Laboratory testing for heparin-induced thrombocytopenia (HIT) has important shortcomings. Immunoassays fail to discriminate platelet-activating from…”
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Distinct Specificity and Single-molecule Kinetics Characterize the Interaction of Pathogenic and Non-pathogenic Antibodies against Platelet Factor 4-Heparin Complexes with Platelet Factor 4 by Litvinov, Rustem I., Yarovoi, Serge V., Rauova, Lubica, Barsegov, Valeri, Sachais, Bruce S., Rux, Ann H., Hinds, Jillian L., Arepally, Gowthami M., Cines, Douglas B., Weisel, John W.

“…Heparin-induced thrombocytopenia (HIT) is a thrombotic complication of heparin therapy mediated by antibodies to complexes between platelet factor 4 (PF4) and…”
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Rational design and characterization of platelet factor 4 antagonists for the study of heparin-induced thrombocytopenia by Sachais, Bruce S., Rux, Ann H., Cines, Douglas B., Yarovoi, Serge V., Garner, Lee I., Watson, Stephen P., Hinds, Jillian L., Rux, John J.

“…Patients with heparin-induced thrombocytopenia (HIT) remain at risk for recurrent thromboembolic complications despite improvements in management. HIT is…”
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Selective Activation of an Apoptotic Retinoid Precursor in Macrophage Cell Lines by Yarovoi, Serge V., Lu, Xian-Ping, Picard, Nathalie, Rungta, Deepa, Rideout, Darryl, Pfahl, Magnus

“…Advances in the understanding of the retinoid signaling mechanism has allowed the discovery of highly selective retinoids that activate only one specific…”
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Atomic description of the immune complex involved in heparin-induced thrombocytopenia by Cai, Zheng, Yarovoi, Serge V., Zhu, Zhiqiang, Rauova, Lubica, Hayes, Vincent, Lebedeva, Tatiana, Liu, Qun, Poncz, Mortimer, Arepally, Gowthami, Cines, Douglas B., Greene, Mark I.

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Atomic Level Description of the Immune Complex That Causes Heparin-Induced Thrombocytopenia (HIT) by Cai, Zheng, Yarovoi, Serge V., Zhu, Zhiquiang, Rauova, Lubica, Lebedeva, Tatiana, Poncz, Mortimer, Arepally, Gowthami M, Cines, Douglas B., Greene, Mark I.

“…Heparin-induced thrombocytopenia (HIT) is thrombotic disorder caused by immune complexes containing antibodies to an antigen composed of platelet factor 4…”
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Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation by Tarui, Takehiko, Akakura, Nobuaki, Majumdar, Mousumi, Andronicos, Nicholas, Takagi, Junichi, Mazar, Andrew P, Bdeir, Khalil, Kuo, Alice, Yarovoi, Serge V, Cines, Douglas B, Takada, Yoshikazu

“…It has been questioned whether there are receptors for urokinase-type plasminogen activator (uPA) that facilitate plasminogen activation other than the high…”
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Human cell lines expressing hormone regulated T7 RNA polymerase localized at distinct intranuclear sites by Yarovoi, Serge V., Pederson, Thoru

“…Although several systems are now available for the controlled expression of eukaryotic genes transcribed by RNA polymerase II, regulated expression has been…”
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Cloning and sequence analysis of cDNA for a human homolog of eubacterial ATP-dependent Lon proteases by Amerik, Alexander Yu, Petukhova, Galina V., Grigorenko, Vitaly G., Lykov, Igor P., Yarovoi, Serge V., Lipkin, Valery M., Gorbalenya, Alexander E.

“…Overlapping cDNA clones containing mRNA for a putative Lon protease (LonHS) were isolated from cDNA libraries prepared from human brain poly(A) + RNA. The…”
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Cloning of cDNA for granzyme-like protein III, a novel serine proteinase from rat duodenum by Grigorenko, Vitaly G., Yarovoi, Serge V., Paulauskaite, Ramune, Amerik, Alexander Yu

“…We previously reported cloning of cDNAs which encode two granzyme-like serine proteinases (GLP I and GLP II) from rat duodenum. In this paper we present the…”
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Identification, sequence analysis, and characterization of cDNA clones encoding two granzyme-like serine proteinases from rat duodenum by Amerik, Alexander Yu, Yarovoi, Serge V., Grigorenko, Vitali G., Antonov, Vladimir K.

“…Clones of cDNA encoding two serine proteinases were isolated from a cDNA library prepared from rat duodenum mRNA. The deduced amino acid sequences consisted of…”
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