Search Results - "Yarosh, Daniel"

Perception and Deception: Human Beauty and the Brain by Yarosh, Daniel B

“…Human physical characteristics and their perception by the brain are under pressure by natural selection to optimize reproductive success. Men and women have…”
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Dynamic visualization of melanosome endo/phagocytosis during melanin transfer using melanosomes pre-stained with carbocyanine dyes by Takeuchi, Seiji, Fukumoto, Takeshi, Nishigori, Chikako, Declercq, Lieve, Yarosh, Daniel B., Mammone, Tomas, Saito, Naoaki

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S-Palmitoylation of Tyrosinase at Cysteine500 Regulates Melanogenesis by Niki, Yoko, Adachi, Naoko, Fukata, Masaki, Fukata, Yuko, Oku, Shinichiro, Makino-Okamura, Chieko, Takeuchi, Seiji, Wakamatsu, Kazumasa, Ito, Shosuke, Declercq, Lieve, Yarosh, Daniel B., Mammone, Tomas, Nishigori, Chikako, Saito, Naoaki, Ueyama, Takehiko

“…Palmitoylation is a lipid modification involving the attachment of palmitic acid to a cysteine residue, thereby affecting protein function. We investigated the…”
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Omeprazole, a Gastric Proton Pump Inhibitor, Inhibits Melanogenesis by Blocking ATP7A Trafficking by Matsui, Mary S., Petris, Michael J., Niki, Yoko, Karaman-Jurukovska, Nevena, Muizzuddin, Neelam, Ichihashi, Masamitsu, Yarosh, Daniel B.

“…Omeprazole is a proton pump inhibitor used in the treatment of peptic ulcer disease and gastrosophageal reflux disease and acts by irreversibly blocking ATP4A,…”
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Six critical questions for DNA repair enzymes in skincare products: a review in dialog by Yarosh, Daniel B, Rosenthal, Amanda, Moy, Ronald

“…Concerns over existing sunscreen filters have reinforced the need to examine supplemental sun protection or repair of sun damage. Technology to enhance DNA…”
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UV-induced DNA damage initiates release of MMP-1 in human skin by Dong, Kelly K., Damaghi, Niusha, Picart, Stephanie D., Markova, Nelli G., Obayashi, Kei, Okano, Yuri, Masaki, Hitoshi, Grether-Beck, Susanne, Krutmann, Jean, Smiles, Kenneth A., Yarosh, Daniel B.

“…:  Destruction of collagen is a hallmark of photoaging. The major enzyme responsible for collagen 1 digestion, matrix metalloproteinase‐1 (MMP‐1), is induced…”
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Melanosomes Are Transferred from Melanocytes to Keratinocytes through the Processes of Packaging, Release, Uptake, and Dispersion by Ando, Hideya, Niki, Yoko, Ito, Masaaki, Akiyama, Kaoru, Matsui, Mary S., Yarosh, Daniel B., Ichihashi, Masamitsu

“…Recent studies have described the role of shedding vesicles as physiological conveyers of intracellular components between neighboring cells. Here we report…”
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Skin cells and tissue are capable of using l-ergothioneine as an integral component of their antioxidant defense system by Markova, Nelli G., Karaman-Jurukovska, Nevena, Dong, Kelly K., Damaghi, Niusha, Smiles, Kenneth A., Yarosh, Daniel B.

“…The cellular defense system against harmful levels of reactive oxygen species consists of antioxidant enzymatic activities and small nonenzymatic molecules…”
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Calcineurin Inhibitors Decrease DNA Repair and Apoptosis in Human Keratinocytes Following Ultraviolet B Irradiation by Yarosh, Daniel B., Pena, Arely V., Nay, Stephanie L., Canning, Matthew T., Brown, David A.

“…The use of calcineurin inhibitors in solid organ transplantation results in an increased risk of skin cancer. We examined the effect of these drugs on DNA…”
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Sirtuin 4 identification in normal human epidermal keratinocytes and its relation to sirtuin 3 and energy metabolism under normal conditions and UVB-induced stress by Dong, Kelly, Pelle, Edward, Yarosh, Daniel B., Pernodet, Nadine

“…:  Sirtuins (SIRT) are NAD+‐dependent deacetylases and ADP‐ribosyltransferases that play a critical role in metabolism and epigenetics. SIRT3 and SIRT4 are of…”
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Anti-inflammatory activity in skin by biomimetic of Evodia rutaecarpa extract from traditional Chinese medicine by Yarosh, Daniel B., Galvin, Jason W., Nay, Stephanie L., Peña, Arely V., Canning, Matthew T., Brown, David A.

“…Wu-Zhu-Yu, is an extract prepared from the small berry fruit of Evodia rutaecarpa and is reported to have anti-inflammatory and anti-nociceptic activity…”
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Increased endogenous DNA oxidation correlates to increased iron levels in melanocytes relative to keratinocytes by Pelle, Edward, Huang, Xi, Zhang, Qi, Pernodet, Nadine, Yarosh, Daniel B, Frenkel, Krystyna

“…The endogenous oxidative state of normal human epidermal melanocytes was investigated and compared to normal human epidermal keratinocytes (NHEKs) in order to…”
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Menopause increases the iron storage protein ferritin in skin by Pelle, Edward, Jian, Jinlong, Zhang, Qi, Muizzuddin, Neelam, Yang, Qing, Dai, Jisen, Maes, Daniel, Pernodet, Nadine, Yarosh, Daniel B, Frenkel, Krystyna, Huang, Xi

“…Menstruation and desquamation are important routes for humans to excrete iron. Because menstruation is no longer available in postmenopausal women, in the…”
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Nuclear and Cell Membrane Effects Contribute Independently to the Induction of Apoptosis in Human Cells Exposed to UVB Radiation by Kulms, Dagmar, Pöppelmann, Birgit, Yarosh, Daniel, Luger, Thomas A., Krutmann, Jean, Schwarz, Thomas

“…UVB-induced DNA damage is a crucial event in UVB-mediated apoptosis. On the other hand, UVB directly activates death receptors on the cell surface including…”
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Protection against UVB-induced oxidative stress in human skin cells and skin models by methionine sulfoxide reductase A by Pelle, Edward, Maes, Daniel, Huang, Xi, Frenkel, Krystyna, Pernodet, Nadine, Yarosh, Daniel B, Zhang, Qi

“…Environmental trauma to human skin can lead to oxidative damage of proteins and affect their activity and structure. When methionine becomes oxidized to its…”
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Topical Treatment with OGG1 Enzyme Affects UVB-induced Skin Carcinogenesis by Wulff, Brian C., Schick, Jonathan S., Thomas-Ahner, Jennifer M., Kusewitt, Donna F., Yarosh, Daniel B., Oberyszyn, Tatiana M.

“…Nonmelanoma skin cancer resulting from UVB exposure is a large and growing problem in the United States. Production of reactive oxygen species (ROS) during the…”
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Protection against ultraviolet A-induced oxidative damage in normal human epidermal keratinocytes under post-menopausal conditions by an ultraviolet A-activated caged-iron chelator: a pilot study by Pelle, Edward, Jian, Jinlong, Declercq, Lieve, Dong, Kelly, Yang, Qing, Pourzand, Charareh, Maes, Daniel, Pernodet, Nadine, Yarosh, Daniel B., Huang, Xi

“…Background/purpose: Human skin is constantly exposed to ultraviolet A (UVA), which can generate reactive oxygen species and cause iron release from ferritin,…”
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Multicenter Phase II Trial of Temozolomide in Mycosis Fungoides/Sézary Syndrome: Correlation with O6-Methylguanine-DNA Methyltransferase and Mismatch Repair Proteins by QUERFELD, Christiane, ROSEN, Steven T, GUITART, Joan, RADEMAKER, Alfred, PEZEN, David S, DOLAN, M. Eileen, BARON, Joseph, YAROSH, Daniel B, FOSS, Francine, KUZEL, Timothy M

“…Temozolomide (TMZ) is an oral derivative of dacarbazine that induces DNA damage by methylating nucleotide bases. Resistance has been associated with high…”
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After sun reversal of DNA damage: enhancing skin repair by Yarosh, Daniel B, Canning, Matthew T, Teicher, Danielle, Brown, David A

“…UV-induced DNA damage has been directly linked to skin cancer, and DNA repair is an important protection against this neoplasm. This is illustrated by the…”
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L-Ergothioneine scavenges superoxide and singlet oxygen and suppresses TNF-alpha and MMP-1 expression in UV-irradiated human dermal fibroblasts by Obayashi, Kei, Kurihara, Kouji, Okano, Yuri, Masaki, Hitoshi, Yarosh, Daniel B

“…Ergothioneine (EGT) is a sulfur-containing amino acid, and is presumed to function as a natural antioxidant. The purpose of this study was to identify the…”
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