Search Results - "Yaron, Jordan R."

Prolonged inflammation leads to ongoing damage after spinal cord injury by Kwiecien, Jacek M, Dabrowski, Wojciech, Dąbrowska-Bouta, Beata, Sulkowski, Grzegorz, Oakden, Wendy, Kwiecien-Delaney, Christian J, Yaron, Jordan R, Zhang, Liqiang, Schutz, Lauren, Marzec-Kotarska, Barbara, Stanisz, Greg J, Karis, John P, Struzynska, Lidia, Lucas, Alexandra R

“…The pathogenesis of spinal cord injury (SCI) remains poorly understood and treatment remains limited. Emerging evidence indicates that post-SCI inflammation is…”
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Rescue of dendritic cells from glycolysis inhibition improves cancer immunotherapy in mice by Inamdar, Sahil, Suresh, Abhirami P., Mangal, Joslyn L., Ng, Nathan D., Sundem, Alison, Wu, Christopher, Lintecum, Kelly, Thumsi, Abhirami, Khodaei, Taravat, Halim, Michelle, Appel, Nicole, Jaggarapu, Madhan Mohan Chandra Sekhar, Esrafili, Arezoo, Yaron, Jordan R., Curtis, Marion, Acharya, Abhinav P.

“…Inhibition of glycolysis in immune cells and cancer cells diminishes their activity, and thus combining immunotherapies with glycolytic inhibitors is…”
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Inflammasome modulation with P2X7 inhibitor A438079-loaded dressings for diabetic wound healing by Yaron, Jordan R, Bakkaloglu, Selin, Grigaitis, Nicole A, Babur, Farhan H, Macko, Sophia, Rhodes, Samantha, Norvor-Davis, Solenne, Rege, Kaushal

“…The inflammasome is a multiprotein complex critical for the innate immune response to injury. Inflammasome activation initiates healthy wound healing, but…”
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In situ light‐activated materials for skin wound healing and repair: A narrative review by Yaron, Jordan R., Gosangi, Mallikarjun, Pallod, Shubham, Rege, Kaushal

“…Dermal wounds are a major global health burden made worse by common comorbidities such as diabetes and infection. Appropriate wound closure relies on a highly…”
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Serine Proteases and Chemokines in Neurotrauma: New Targets for Immune Modulating Therapeutics in Spinal Cord Injury by Beladi, Roxana N, Varkoly, Kyle S, Schutz, Lauren, Zhang, Liqiang, Yaron, Jordan R, Guo, Qiuyun, Burgin, Michelle, Hogue, Ian, Tierney, Wesley, Dobrowski, Wojciech, Lucas, Alexandra R

“…Progressive neurological damage after brain or spinal cord trauma causes loss of motor function and treatment is very limited. Clotting and hemorrhage occur…”
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Fibrinolytic Serine Proteases, Therapeutic Serpins and Inflammation: Fire Dancers and Firestorms by Yaron, Jordan R, Zhang, Liqiang, Guo, Qiuyun, Haydel, Shelley E, Lucas, Alexandra R

“…The making and breaking of clots orchestrated by the thrombotic and thrombolytic serine protease cascades are critical determinants of morbidity and mortality…”
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The Role of Astrogliosis in Formation of the Syrinx in Spinal Cord Injury by Kwiecien, Jacek M, Dąbrowski, Wojciech, Yaron, Jordan R, Zhang, Liqiang, Delaney, Kathleen H, Lucas, Alexandra R

“…A massive localized trauma to the spinal cord results in complex pathologic events driven by necrosis and vascular damage which in turn leads to hemorrhage and…”
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Selective Deletion of Heparan Sulfotransferase Enzyme, Ndst1, in Donor Endothelial and Myeloid Precursor Cells Significantly Decreases Acute Allograft Rejection by Chen, Hao, Ambadapadi, Sriram, Wakefield, Dara, Bartee, Meeyong, Yaron, Jordan R., Zhang, Liqiang, Archer-Hartmann, Stephanie A., Azadi, Parastoo, Burgin, Michelle, Borges, Chad, Zheng, Donghang, Ergle, Kevin, Muppala, Vishnu, Morshed, Sufi, Rand, Kenneth, Clapp, William, Proudfoot, Amanda, Lucas, Alexandra

“…Early damage to transplanted organs initiates excess inflammation that can cause ongoing injury, a leading cause for late graft loss. The endothelial…”
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Temporal evaluation of efficacy and quality of tissue repair upon laser‐activated sealing by Ghosh, Deepanjan, Salinas, Christopher M., Pallod, Shubham, Roberts, Jordan, Makin, Inder Raj S., Yaron, Jordan R., Witte, Russell S., Rege, Kaushal

“…Injuries caused by surgical incisions or traumatic lacerations compromise the structural and functional integrity of skin. Immediate approximation and robust…”
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Myxoma virus derived immune modulating proteins, M-T7 and Serp-1, reduce early inflammation after spinal cord injury in the rat model by Kwiecien, Jacek M, Dabrowski, Wojciech, Marzec-Kotarska, Barbara, Kwiecien-Delaney, Christian J, Yaron, Jordan R, Zhang, Liqiang, Schutz, Lauren, Lucas, Alexandra R

“…Spinal cord injury (SCI)-initiated inflammation was treated with anti-inflammatory reagents. We compared local spinal cord or intraperitoneal infusion of two…”
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c-Src regulates cargo transit via the Golgi in pancreatic acinar cells by Kostenko, Sergiy, Heu, Chan C., Yaron, Jordan R., Singh, Garima, de Oliveira, Cristiane, Muller, William J., Singh, Vijay P.

“…The exocrine pancreatic acinar cell is unique for its rapid protein synthesis and packaging in zymogen granules (ZGs). However, while crucial to the…”
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Characterization and Predictive Value of Near Infrared 2-Deoxyglucose Optical Imaging in Severe Acute Pancreatitis by de Oliveira, Cristiane, Patel, Krutika, Mishra, Vivek, Trivedi, Ram N, Noel, Pawan, Singh, Abhilasha, Yaron, Jordan R, Singh, Vijay P

“…Studying the uptake of 2-deoxy glucose (2-DG) analogs such as 2-Deoxy-2-[18F] fluoroglucose (FDG) is a common approach to identify and monitor malignancies and…”
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Recombinant Myxoma Virus -Derived Immune Modulator M-T7 Accelerates Cutaneous Wound Healing and Improves Tissue Remodeling by Yaron, Jordan R, Zhang, Liqiang, Guo, Qiuyun, Awo, Enkidia A, Burgin, Michelle, Schutz, Lauren N, Zhang, Nathan, Kilbourne, Jacquelyn, Daggett-Vondras, Juliane, Lowe, Kenneth M, Lucas, Alexandra R

“…Complex dermal wounds represent major medical and financial burdens, especially in the context of comorbidities such as diabetes, infection and advanced age…”
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Neuroprotective Effect of Subdural Infusion of Serp-1 in Spinal Cord Trauma by Kwiecien, Jacek M, Dabrowski, Wojciech, Kwiecien-Delaney, Bryce J, Kwiecien-Delaney, Christian J, Siwicka-Gieroba, Dorota, Yaron, Jordan R, Zhang, Liqiang, Delaney, Kathleen H, Lucas, Alexandra R

“…Spinal cord injury (SCI) initiates a severe, destructive inflammation with pro-inflammatory, CD68+/CD163-, phagocytic macrophages infiltrating the area of…”
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Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis by Ju, Brent, Guo, Owen, Benissan-Messan, Dathe Z, Shawver, McKinley H, Chen, Peng, Geng, Bingchuan, Wei, Siqi, Yaron, Jordan R, Lucas, Alexandra R, Zhu, Hua

“…Chemical corneal injuries carry a high morbidity and commonly lead to visual impairment. Here, we investigate the role of Serp-1, a serine protease inhibitor,…”
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Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice by Yaron, Jordan R, Chen, Hao, Ambadapadi, Sriram, Zhang, Liqiang, Tafoya, Amanda M, Munk, Barbara H, Wakefield, Dara N, Fuentes, Jorge, Marques, Bruno J, Harripersaud, Krishna, Bartee, Mee Yong, Davids, Jennifer A, Zheng, Donghang, Rand, Kenneth, Dixon, Lisa, Moyer, Richard W, Clapp, William L, Lucas, Alexandra R

“…Ischemia-reperfusion injury (IRI) is an antigen-independent, innate immune response to arterial occlusion and ischemia with subsequent paradoxical exacerbation…”
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PEGylated Serp-1 Markedly Reduces Pristane-Induced Experimental Diffuse Alveolar Hemorrhage, Altering uPAR Distribution, and Macrophage Invasion by Guo, Qiuyun, Yaron, Jordan R, Wallen, 3rd, John W, Browder, Kyle F, Boyd, Ryan, Olson, Tien L, Burgin, Michelle, Ulrich, Peaches, Aliskevich, Emily, Schutz, Lauren N, Fromme, Petra, Zhang, Liqiang, Lucas, Alexandra R

“…Diffuse alveolar hemorrhage (DAH) is one of the most serious clinical complications of systemic lupus erythematosus (SLE). The prevalence of DAH is reported to…”
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Mouse Gamma Herpesvirus MHV-68 Induces Severe Gastrointestinal (GI) Dilatation in Interferon Gamma Receptor-Deficient Mice (IFNγR -/- ) That Is Blocked by Interleukin-10 by Chen, Hao, Bartee, Mee Yong, Yaron, Jordan R, Liu, Liying, Zhang, Liqiang, Zheng, Donghang, Hogue, Ian B, Bullard, Whitney L, Tibbetts, Scott, Lucas, Alexandra R

“…Inflammatory bowel disease (IBD) and infection cause gastrointestinal (GI) distension and, in severe cases, toxic megacolon with risk of perforation and death…”
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RNA Virus Gene Signatures Detected in Patients With Cardiomyopathy After Chemotherapy; A Pilot Study by Varkoly, Kyle, Tan, Shaoyuan, Beladi, Roxana, Fonseca, David, Zanetti, Isabela Rivabem, Kraberger, Simona, Shah, Chintan, Yaron, Jordan R, Zhang, Liqiang, Juby, Michael, Fath, Ayman, Ambadapadi, Sriram, House, Melanie, Maranian, Paul, Pepine, Carl J, Varsani, Arvind, Moreb, Jan, Schultz-Cherry, Stacey, Lucas, Alexandra R

“…Viral infections are pervasive and leading causes of myocarditis. Immune-suppression after chemotherapy increases opportunistic infections, but the incidence…”
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Virus-Derived Chemokine Modulating Protein Pre-Treatment Blocks Chemokine-Glycosaminoglycan Interactions and Significantly Reduces Transplant Immune Damage by Zanetti, Isabela R, Burgin, Michelle, Zhang, Liqiang, Yeh, Steve T, Ambadapadi, Sriram, Kilbourne, Jacquelyn, Yaron, Jordan R, Lowe, Kenneth M, Daggett-Vondras, Juliane, Fonseca, David, Boyd, Ryan, Wakefield, Dara, Clapp, William, Lim, Efrem, Chen, Hao, Lucas, Alexandra

“…Immune cell invasion after the transplantation of solid organs is directed by chemokines binding to glycosaminoglycans (GAGs), creating gradients that guide…”
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