Search Results - "Yaron, Jordan"

Prolonged inflammation leads to ongoing damage after spinal cord injury by Kwiecien, Jacek M, Dabrowski, Wojciech, Dąbrowska-Bouta, Beata, Sulkowski, Grzegorz, Oakden, Wendy, Kwiecien-Delaney, Christian J, Yaron, Jordan R, Zhang, Liqiang, Schutz, Lauren, Marzec-Kotarska, Barbara, Stanisz, Greg J, Karis, John P, Struzynska, Lidia, Lucas, Alexandra R

“…The pathogenesis of spinal cord injury (SCI) remains poorly understood and treatment remains limited. Emerging evidence indicates that post-SCI inflammation is…”
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Bioactive nanomaterials kickstart early repair processes and potentiate temporally modulated healing of healthy and diabetic wounds by Ghosh, Deepanjan, Yaron, Jordan R., Abedin, Muhammad Raisul, Godeshala, Sudhakar, Kumar, Suneel, Kilbourne, Jacquelyn, Berthiaume, Francois, Rege, Kaushal

“…Slow-healing and chronic wounds represent a major global economic and medical burden, and there is significant unmet need for novel therapies which act to both…”
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A Highly Selective Mitochondria-Targeting Fluorescent K+ Sensor by Kong, Xiangxing, Su, Fengyu, Zhang, Liqiang, Yaron, Jordan, Lee, Fred, Shi, Zhengwei, Tian, Yanqing, Meldrum, Deirdre R.

“…Regulation of intracellular potassium (K+) concentration plays a key role in metabolic processes. So far, only a few intracellular K+ sensors have been…”
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Rescue of dendritic cells from glycolysis inhibition improves cancer immunotherapy in mice by Inamdar, Sahil, Suresh, Abhirami P., Mangal, Joslyn L., Ng, Nathan D., Sundem, Alison, Wu, Christopher, Lintecum, Kelly, Thumsi, Abhirami, Khodaei, Taravat, Halim, Michelle, Appel, Nicole, Jaggarapu, Madhan Mohan Chandra Sekhar, Esrafili, Arezoo, Yaron, Jordan R., Curtis, Marion, Acharya, Abhinav P.

“…Inhibition of glycolysis in immune cells and cancer cells diminishes their activity, and thus combining immunotherapies with glycolytic inhibitors is…”
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Copper-Eluting Fibers for Enhanced Tissue Sealing and Repair by Ghosh, Deepanjan, Godeshala, Sudhakar, Nitiyanandan, Rajeshwar, Islam, Md Saiful, Yaron, Jordan R, DiCaudo, David, Kilbourne, Jacquelyn, Rege, Kaushal

“…Copper ions play an important role in several physiological processes, including angiogenesis, growth factor induction and extracellular matrix remodeling,…”
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Skin repair and infection control in diabetic, obese mice using bioactive laser-activated sealants by Pallod, Shubham, Aguilera Olvera, Rodrigo, Ghosh, Deepanjan, Rai, Lama, Brimo, Souzan, DeCambra, Weston, Sant, Harsh Girish, Ristich, Eron, Singh, Vanshika, Abedin, Muhammad Raisul, Chang, Nicolas, Yarger, Jeffery L., Lee, Jung Keun, Kilbourne, Jacquelyn, Yaron, Jordan R., Haydel, Shelley E., Rege, Kaushal

“…Conventional wound approximation devices, including sutures, staples, and glues, are widely used but risk of wound dehiscence, local infection, and scarring…”
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Succinate in the tumor microenvironment affects tumor growth and modulates tumor associated macrophages by Inamdar, Sahil, Suresh, Abhirami P., Mangal, Joslyn L., Ng, Nathan D., Sundem, Alison, Behbahani, Hoda Shokrollahzadeh, Rubino, Thomas E., Yaron, Jordan R., Khodaei, Taravat, Green, Matthew, Curtis, Marion, Acharya, Abhinav P.

“…Succinate is an important metabolite that modulates metabolism of immune cells and cancer cells in the tumor microenvironment (TME). Herein, we report that…”
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A Mouse Model of Acute Liver Injury by Warm, Partial Ischemia-Reperfusion for Testing the Efficacy of Virus-Derived Therapeutics by Yaron, Jordan R, Zhang, Liqiang, Guo, Qiuyun, Chen, Hao, Lucas, Alexandra R

“…Ischemia-reperfusion injury (IRI) drives early and long-term damage to organs as well as compounding damage from acute transplant rejection and surgical…”
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Inflammasome modulation with P2X7 inhibitor A438079-loaded dressings for diabetic wound healing by Yaron, Jordan R, Bakkaloglu, Selin, Grigaitis, Nicole A, Babur, Farhan H, Macko, Sophia, Rhodes, Samantha, Norvor-Davis, Solenne, Rege, Kaushal

“…The inflammasome is a multiprotein complex critical for the innate immune response to injury. Inflammasome activation initiates healthy wound healing, but…”
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In situ light‐activated materials for skin wound healing and repair: A narrative review by Yaron, Jordan R., Gosangi, Mallikarjun, Pallod, Shubham, Rege, Kaushal

“…Dermal wounds are a major global health burden made worse by common comorbidities such as diabetes and infection. Appropriate wound closure relies on a highly…”
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Alpha‐ketoglutaric acid based polymeric particles for cutaneous wound healing by Jaggarapu, Madhan M. C. S., Ghosh, Deepanjan, Johnston, Tyler, Yaron, Jordan R., Mangal, Joslyn L., Inamdar, Sahil, Gosangi, Mallikarjun, Rege, Kaushal, Acharya, Abhinav P.

“…Metabolites are not only involved in energy pathways but can also act as signaling molecules. Herein, we demonstrate that polyesters of alpha‐ketoglutararte…”
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Succinate based polymers drive immunometabolism in dendritic cells to generate cancer immunotherapy by Inamdar, Sahil, Suresh, Abhirami P., Mangal, Joslyn L., Ng, Nathan D., Sundem, Alison, Behbahani, Hoda Shokrollahzadeh, Rubino, Thomas E., Shi, Xiaojian, Loa, Sharon T., Yaron, Jordan R., Hitosugi, Taro, Green, Matthew, Gu, Haiwei, Curtis, Marion, Acharya, Abhinav P.

“…Boosting the metabolism of immune cells while restricting cancer cell metabolism is challenging. Herein, we report that using biomaterials for the controlled…”
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Correction to “Copper-Eluting Fibers for Enhanced Tissue Sealing and Repair” by Ghosh, Deepanjan, Godeshala, Sudhakar, Nitiyanandan, Rajeshwar, Islam, Md Saiful, Yaron, Jordan R, DiCaudo, David, Kilbourne, Jacquelyn, Rege, Kaushal

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Characterization and Predictive Value of Near Infrared 2-Deoxyglucose Optical Imaging in Severe Acute Pancreatitis by de Oliveira, Cristiane, Patel, Krutika, Mishra, Vivek, Trivedi, Ram N, Noel, Pawan, Singh, Abhilasha, Yaron, Jordan R, Singh, Vijay P

“…Studying the uptake of 2-deoxy glucose (2-DG) analogs such as 2-Deoxy-2-[18F] fluoroglucose (FDG) is a common approach to identify and monitor malignancies and…”
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Neurologic and Histologic Tests Used to Measure Neuroprotective Effectiveness of Virus-Derived Immune-Modulating Proteins by Kwiecien, Jacek M, Yaron, Jordan R, Delaney, Kathleen H, Lucas, Alexandra R

“…Severe inflammatory disease initiated by neurotrauma and stroke is of primary concern in these intractable pathologies as noted in recent studies and…”
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Kidney Subcapsular Allograft Transplants as a Model to Test Virus-Derived Chemokine-Modulating Proteins as Therapeutics by Burgin, Michelle, Yaron, Jordan R, Zhang, Liqiang, Guo, Qiuyun, Daggett, Juliane, Kilbourne, Jacquelyn, Lowe, Kenneth M, Lucas, Alexandra R

“…Solid tissue transplant is a growing medical need that is further complicated by a limited donor organ supply. Acute and chronic rejection occurs in nearly all…”
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Serine Proteases and Chemokines in Neurotrauma: New Targets for Immune Modulating Therapeutics in Spinal Cord Injury by Beladi, Roxana N, Varkoly, Kyle S, Schutz, Lauren, Zhang, Liqiang, Yaron, Jordan R, Guo, Qiuyun, Burgin, Michelle, Hogue, Ian, Tierney, Wesley, Dobrowski, Wojciech, Lucas, Alexandra R

“…Progressive neurological damage after brain or spinal cord trauma causes loss of motor function and treatment is very limited. Clotting and hemorrhage occur…”
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Fibrinolytic Serine Proteases, Therapeutic Serpins and Inflammation: Fire Dancers and Firestorms by Yaron, Jordan R, Zhang, Liqiang, Guo, Qiuyun, Haydel, Shelley E, Lucas, Alexandra R

“…The making and breaking of clots orchestrated by the thrombotic and thrombolytic serine protease cascades are critical determinants of morbidity and mortality…”
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Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox by Khatua, Biswajit, El-Kurdi, Bara, Patel, Krutika, Rood, Christopher, Noel, Pawan, Crowell, Michael, Yaron, Jordan R, Kostenko, Sergiy, Guerra, Andre, Faigel, Douglas O, Lowe, Mark, Singh, Vijay P

“…Obesity sometimes seems protective in disease. This obesity paradox is predominantly described in reports from the Western Hemisphere during acute illnesses…”
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Ringer's Lactate Prevents Early Organ Failure by Providing Extracellular Calcium by Khatua, Biswajit, Yaron, Jordan R, El-Kurdi, Bara, Kostenko, Sergiy, Papachristou, Georgios I, Singh, Vijay P

“…Ringer's lactate may improve early systemic inflammation during critical illnesses like severe acute pancreatitis, which are associated with hypocalcemia…”
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