Search Results - "Yarlagadda, S."

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430 by Warren, Travis K., Wells, Jay, Panchal, Rekha G., Stuthman, Kelly S., Garza, Nicole L., Van Tongeren, Sean A., Dong, Lian, Retterer, Cary J., Eaton, Brett P., Pegoraro, Gianluca, Honnold, Shelley, Bantia, Shanta, Kotian, Pravin, Chen, Xilin, Taubenheim, Brian R., Welch, Lisa S., Minning, Dena M., Babu, Yarlagadda S., Sheridan, William P., Bavari, Sina

“…A broad-spectrum antiviral small molecule is reported to act as an inhibitor of viral polymerase activity and is shown to be effective in protecting non-human…”
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Temperature dependence of long coherence times of oxide charge qubits by Dey, A., Yarlagadda, S.

“…The ability to maintain coherence and control in a qubit is a major requirement for quantum computation. We show theoretically that long coherence times can be…”
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BCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model by Julander, Justin G, Bantia, Shanta, Taubenheim, Brian R, Minning, Dena M, Kotian, Pravin, Morrey, John D, Smee, Donald F, Sheridan, William P, Babu, Yarlagadda S

“…No effective antiviral therapies are currently available to treat disease after infection with yellow fever virus (YFV). A Syrian golden hamster model of…”
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Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE) by Kotian, Pravin L, Wu, Minwan, Vadlakonda, Satish, Chintareddy, Venkat, Lu, Pengcheng, Juarez, Luis, Kellogg-Yelder, Debra, Chen, Xilin, Muppa, Saritha, Chambers-Wilson, Ramanda, Davis Parker, Cynthia, Williams, Jason, Polach, Kevin J, Zhang, Weihe, Raman, Krishnan, Babu, Yarlagadda S

“…Hereditary angioedema (HAE) is a rare and potentially life-threatening disease that affects an estimated 1 in 50 000 individuals worldwide. Until recently,…”
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Activity of Galidesivir in a Hamster Model of SARS-CoV-2 by Taylor, Ray, Bowen, Richard, Demarest, James F, DeSpirito, Michael, Hartwig, Airn, Bielefeldt-Ohmann, Helle, Walling, Dennis M, Mathis, Amanda, Babu, Yarlagadda S

“…Coronavirus disease 2019 (COVID-19) has claimed the lives of millions of people worldwide since it first emerged. The impact of the COVID-19 pandemic on public…”
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Decoherence in models for hard-core bosons coupled to optical phonons by Dey, A., Lone, M. Q., Yarlagadda, S.

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Stronger inflammatory cytotoxic T-cell response in women identified by microarray analysis by Hewagama, A, Patel, D, Yarlagadda, S, Strickland, F M, Richardson, B C

“…Women develop chronic inflammatory autoimmune diseases more often than men. The mechanisms causing the increased susceptibility are incompletely understood…”
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A direct-acting antiviral drug abrogates viremia in Zika virus-infected rhesus macaques by Lim, So-Yon, Osuna, Christa E, Best, Katharine, Taylor, Ray, Chen, Elsa, Yoon, Gyeol, Kublin, Jessica L, Schalk, Dane, Schultz-Darken, Nancy, Capuano, Saverio, Safronetz, David, Luo, Ma, MacLennan, Steve, Mathis, Amanda, Babu, Yarlagadda S, Sheridan, William P, Perelson, Alan S, Whitney, James B

“…Zika virus infection in humans has been associated with serious reproductive and neurological complications. At present, no protective antiviral drug treatment…”
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Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model by Cassera, María B, Hazleton, Keith Z, Merino, Emilio F, Obaldia, 3rd, Nicanor, Ho, Meng-Chiao, Murkin, Andrew S, DePinto, Richard, Gutierrez, Jemy A, Almo, Steven C, Evans, Gary B, Babu, Yarlagadda S, Schramm, Vern L

“…Plasmodium falciparum causes most of the one million annual deaths from malaria. Drug resistance is widespread and novel agents against new targets are needed…”
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A time-domain reflectometry method for automated measurement of crack propagation in composites during mode I DCB testing under cold, hot, and hot/wet conditions by Abuobaid, A, Heider, D, Yarlagadda, S

“…This article describes an automated method for the measurement of crack initiation and propagation in composite materials during modeI double cantilever beam…”
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Synthesis of novel azasugar-containing 2'β-C-Me 9-deaza nucleosides as potential anti-hepatitis C virus agents by Kotian, Pravin L., Wu, Minwan, Ghosh, Ajit, Polach, Kevin J., El-Kattan, Yahya, Kumar, V. Satish, Lin, Tsu-Hsing, Cheng, Xiaogang, Bantia, Shanta, Raman, Krishnan, Chand, Pooran, Babu, Yarlagadda S.

“…As a part of our ongoing discovery efforts exploring azasugar as agents for treating various unmet medical needs, we prepared analogs of azasugar as potential…”
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Combined effects of kink bands and hygrothermal conditioning on tensile strength of polyarylate liquid crystal co-polymer and aramid fibers by Abu Obaid, A, Yarlagadda, S, Gillespie, JW

“…Translation of tensile properties from high-performance fibers to end-use fabrics is sensitive to weaving-induced filament defects and environmental exposure…”
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Association between delayed graft function and allograft and patient survival: a systematic review and meta-analysis by Yarlagadda, Sri G., Coca, Steven G., Formica, Richard N., Poggio, Emilio D., Parikh, Chirag R.

“…Background. Delayed graft function (DGF) is a common complication of renal transplantation. The short-term consequences of DGF are well known, but the…”
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Open-Set Source Attribution for Panchromatic Satellite Imagery by Cannas, E. D., Baireddy, S., Bartusiak, E. R., Yarlagadda, S. K., Montserrat, D. Mas, Bestagini, P., Tubaro, S., Delp, E. J.

“…In the last few years, several companies started offering the possibility of buying different kinds of overhead images acquired by satellites orbiting around…”
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Marked variation in the definition and diagnosis of delayed graft function: a systematic review by Yarlagadda, Sri G., Coca, Steven G., Garg, Amit X., Doshi, Mona, Poggio, Emilio, Marcus, Richard J., Parikh, Chirag R.

“…Background. The term delayed graft function (DGF) is commonly used to describe the need for dialysis after receiving a kidney transplant. DGF increases…”
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Hysteresis heating based induction bonding of thermoplastic composites by Suwanwatana, W., Yarlagadda, S., Gillespie, J.W.

“…The bonding of polymer matrix composites using magnetic particulate susceptor materials for hysteresis induction heating is investigated in this study…”
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Deepfakes Detection with Automatic Face Weighting by Montserrat, Daniel Mas, Hao, Hanxiang, Yarlagadda, S. K., Baireddy, Sriram, Shao, Ruiting, Horvath, Janos, Bartusiak, Emily, Yang, Justin, Guera, David, Zhu, Fengqing, Delp, Edward J.

“…Altered and manipulated multimedia is increasingly present and widely distributed via social media platforms. Advanced video manipulation tools enable the…”
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Influence of particle size on hysteresis heating behavior of nickel particulate polymer films by Suwanwatana, W., Yarlagadda, S., Gillespie, J.W.

“…The viability of using magnetic particulate susceptor materials for induction heating during bonding of polymer matrix composites is investigated in this work…”
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Blood group A isoagglutinins in A(2) → O simultaneous liver/kidney transplantation may not influence kidney function by Bryan, C F, Abdulkarim, B, Nawabi, A, Stewart, D, Yarlagadda, S G

“…We simultaneously transplanted a liver and kidney (SLK) into a 55-year-old woman with end-stage liver disease secondary to recurrent primary biliary cirrhosis…”
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Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes—A novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies by Bantia, Shanta, Parker, Cynthia, Upshaw, Ramanda, Cunningham, Amanda, Kotian, Pravin, Kilpatrick, J. Michael, Morris, Philip, Chand, Pooran, Babu, Yarlagadda S.

“…The profound suppression of T-cell immunity seen in purine nucleoside phosphorylase (PNP; EC 2.4.2.1) deficient patients supports potential application of…”
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