Search Results - "Yarham, Janet M"

Distinctive profile of IsomiR expression and novel microRNAs in rat heart left ventricle by McGahon, Mary K, Yarham, Janet M, Daly, Aideen, Guduric-Fuchs, Jasenka, Ferguson, Lyndsey J, Simpson, David A, Collins, Anthony

“…MicroRNAs (miRNAs) are single-stranded non-coding RNAs that negatively regulate target gene expression through mRNA cleavage or translational repression. There…”
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A novel dual-fluorescence strategy for functionally validating microRNA targets in 3' untranslated regions: regulation of the inward rectifier potassium channel K(ir)2.1 by miR-212 by Goldoni, Dana, Yarham, Janet M, McGahon, Mary K, O'Connor, Anna, Guduric-Fuchs, Jasenka, Edgar, Kevin, McDonald, Denise M, Simpson, David A, Collins, Anthony

“…Gene targeting by microRNAs is important in health and disease. We developed a functional assay for identifying microRNA targets and applied it to the K(+)…”
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Next‐generation sequencing analysis of rat heart left ventricle: novel microRNAs, novel isomiRs and transmural distribution of microRNA expression by Collins, Anthony, McGahon, Mary K, Yarham, Janet M, Daly, Aideen, Guduric‐Fuchs, Jasenka, Simpson, David A

“…Abstract only MicroRNAs (miRNAs) have a significant role in regulating gene expression in heart disease. They can exist as isoforms (isomiRs) that are…”
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Targeting of Kir2.1 and Downregulation of Inward Rectifier K+ Current by miR-212 by Goldoni, Dana, Yarham, Janet M., McGahon, Mary K., O’Connor, Anna, Guduric-Fuchs, Jasenka, Edgar, Kevin, McDonald, Denise M., Simpson, David A., Collins, Anthony

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