Search Results - "Yap, Chui Sun"

Kinetic profiling of the c-Myc transcriptome and bioinformatic analysis of repressed gene promoters by Yap, Chui-Sun, Peterson, Abigail L., Castellani, Gastone, Sedivy, John M., Neretti, Nicola

“…Mammalian c-Myc is a member of a small family of three related proto-oncogenic transcription factors. c-Myc has an unusually broad array of regulatory…”
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Identification of KMT2D and KDM6A variants by targeted sequencing from patients with Kabuki syndrome and other congenital disorders by Yap, Chui-Sun, Jamuar, Saumya Shekhar, Lai, Angeline H.M., Tan, Ee-Shien, Ng, Ivy, Ting, Teck Wah, Tan, Ene-Choo

“…•Targeted next-generation sequencing was performed on 19 patients with congenital disorders.•12 heterozygous KMT2D variants were identified among 13 patients…”
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Exploiting the TRIP-Br family of cell cycle regulatory proteins as chemotherapeutic drug targets in human cancer by Zang, Zhi Jiang, Sim, Khe Guan, Cheong, Jit Kong, Yang, Christopher Maolin, Yap, Chui Sun, I-Hong Hsu, Stephen

“…TRIP-Br1 and TRIP-Br2 are potent cell growth promoting factors that function as components of the E2F1/DP1 transcription complex to integrate positive growth…”
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Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells by Yap, Chui Sun, Sinha, Rohit Anthony, Ota, Sho, Katsuki, Masahito, Yen, Paul Michael

“…•Thyroid hormone induces miR-181d expression in human hepatic cells and mouse livers.•Thyroid hormone downregulates CDX2 and SOAT2 (or ACAT2) via…”
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An integrative approach identified genes associated with drug response in gastric cancer by Zhou, Jin, Yong, Wei-Peng, Yap, Chui Sun, Vijayaraghavan, Aadhitthya, Sinha, Rohit Anthony, Singh, Brijesh Kumar, Xiu, Sam, Manesh, Sravanthy, Ngo, Anna, Lim, Andrea, Ang, Carolyn, Xie, Chen, Wong, Foong Ying, Lin, Suling J, Wan, Wei Keat, Tan, Iain Beehuat, Flotow, Horst, Tan, Patrick, Lim, Kiat-Hon, Yen, Paul Michael, Goh, Liang Kee

“…Gastric cancer (GC) is the second leading cause of global cancer mortality worldwide. However, the molecular mechanism underlying its carcinogenesis and drug…”
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Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library by Zhou, Jin, Chen, Geng Bo, Tang, Yew Chung, Sinha, Rohit Anthony, Wu, Yonghui, Yap, Chui Sun, Wang, Guihua, Hu, Junbo, Xia, Xianmin, Tan, Patrick, Goh, Liang Kee, Yen, Paul Michael

“…While there is strong evidence for phosphatidylinositol 3-kinase (PI3K) involvement in cancer development, there is limited information about the role of PI3K…”
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Mesenchymal Stromal Cell (MSC)-Derived Combination of CXCL5 and Anti-CCL24 Is Synergistic and Superior to MSC and Cyclosporine for the Treatment of Graft-versus-Host Disease by Fan, Xiubo, Guo, Dianyang, Cheung, Alice M.S., Poon, Zhi Yong, Yap, Chui Sun, Goh, Shane Ee, Guo, Dianyan, Li, Huihua, Bari, Sudipto, Li, Shang, Lim, Kiat Hon, Hwang, William Ying Khee

“…•MSCs regulate immunosuppression via upregulating CXCL5 and downregulating CCL24.•A synergistic 2-factor combination (2FC) of CXCL5 and anti-CCL24 ameliorates…”
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A bioinformatics approach to the understanding of c-Myc biology by Yap, Chui Sun

“…c-Myc is an oncogenic transcription factor that is deregulated in many human cancers. It is a broad and weak transcription factor, regulating the expression of…”
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A bioinformatics approach to the understanding of c-Myc biology by Yap, Chui Sun

“…c-Myc is an oncogenic transcription factor that is deregulated in many human cancers. It is a broad and weak transcription factor, regulating the expression of…”
Get full text