Search Results - "Yao Lan"

Macrophages: versatile players in renal inflammation and fibrosis by Tang, Patrick Ming-Kuen, Nikolic-Paterson, David J., Lan, Hui-Yao

“…Macrophages have important roles in immune surveillance and in the maintenance of kidney homeostasis; their response to renal injury varies enormously…”
Get full text

Renal tubule injury: a driving force toward chronic kidney disease by Liu, Bi-Cheng, Tang, Tao-Tao, Lv, Lin-Li, Lan, Hui-Yao

“…Renal tubules are the major component of the kidney and are vulnerable to a variety of injuries including hypoxia, proteinuria, toxins, metabolic disorders,…”
Get more information

TGF-Beta as a Master Regulator of Diabetic Nephropathy by Wang, Li, Wang, Hong-Lian, Liu, Tong-Tong, Lan, Hui-Yao

“…Diabetic nephropathy (DN) is one of the most common complications in diabetes mellitus and the leading cause of end-stage renal disease. TGF-β is a pleiotropic…”
Get full text

Quercetin protects against cisplatin‐induced acute kidney injury by inhibiting Mincle/Syk/NF‐κB signaling maintained macrophage inflammation by Tan, Rui‐Zhi, Wang, Chen, Deng, Chong, Zhong, Xia, Yan, Ying, Luo, Yi, Lan, Hui‐Yao, He, Tao, Wang, Li

“…Acute kidney injury (AKI) with high incidence and mortality is the main cause of chronic kidney disease. Previous studies have indicated that quercetin, an…”
Get full text

TGF-β Signaling: From Tissue Fibrosis to Tumor Microenvironment by Chung, Jeff Yat-Fai, Chan, Max Kam-Kwan, Li, Jane Siu-Fan, Chan, Alex Siu-Wing, Tang, Philip Chiu-Tsun, Leung, Kam-Tong, To, Ka-Fai, Lan, Hui-Yao, Tang, Patrick Ming-Kuen

“…Transforming growth factor-β (TGF-β) signaling triggers diverse biological actions in inflammatory diseases. In tissue fibrosis, it acts as a key pathogenic…”
Get full text

C‐reactive protein and ageing by Tang, Ying, Fung, Erik, Xu, Anping, Lan, Hui‐Yao

“…Summary Increasing evidence shows that C‐reactive protein (CRP) is not only an inflammatory biomarker but also an important risk factor associated with…”
Get full text

Quercetin as a potential treatment for COVID-19-induced acute kidney injury: Based on network pharmacology and molecular docking study by Gu, Yue-Yu, Zhang, Min, Cen, Huan, Wu, Yi-Fan, Lu, Zhaoyu, Lu, Fuhua, Liu, Xu-Sheng, Lan, Hui-Yao

“…Kidneys are one of the targets for SARS-CoV-2, it is reported that up to 36% of patients with SARS-CoV-2 infection would develop into acute kidney injury…”
Get full text

GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy by Li, Yinshuang, Yuan, Ying, Huang, Zhong-xing, Chen, Hui, Lan, Ruilong, Wang, Zeng, Lai, Kunmei, Chen, Hong, Chen, Zhimin, Zou, Zhenhuan, Ma, Hua-bin, Lan, Hui-Yao, Mak, Tak W., Xu, Yanfang

“…Renal tubular cell (RTC) death and inflammation contribute to the progression of obstructive nephropathy, but its underlying mechanisms have not been fully…”
Get full text

Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury by Lv, Lin-Li, Feng, Ye, Wu, Min, Wang, Bin, Li, Zuo-Lin, Zhong, Xin, Wu, Wei-Jun, Chen, Jun, Ni, Hai-Feng, Tang, Tao-Tao, Tang, Ri-Ning, Lan, Hui-Yao, Liu, Bi-Cheng

“…Tubulointerstitial inflammation is a common characteristic of acute and chronic kidney injury. However, the mechanism by which the initial injury of tubular…”
Get full text

A study of market segmentation, government competition, and public service efficiency in China: Based on a semi-parametric spatial lag model by Yao, Lan, Luo, Ruoyu, Yi, Xiaoqin

“…Despite significant growth in fiscal expenditure, the overall level of public services in China remains inadequate. One approach to improving government public…”
Get full text

Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury by Wang, Ying-Ying, Jiang, Hong, Pan, Jun, Huang, Xiao-Ru, Wang, Yu-Cheng, Huang, Hong-Feng, To, Ka-Fai, Nikolic-Paterson, David J, Lan, Hui-Yao, Chen, Jiang-Hua

“…Interstitial fibrosis is an important contributor to graft loss in chronic renal allograft injury. Inflammatory macrophages are associated with fibrosis in…”
Get full text

Therapeutic perspective: evolving evidence of nonsteroidal mineralocorticoid receptor antagonists in diabetic kidney disease by Yao, Lan, Liang, Xianhui, Wang, Pei

“…Approximately 30%-40% of patients with type 1 or type 2 diabetes (T1D/T2D) develop diabetic kidney disease (DKD), which can lead to end-stage kidney disease…”
Get more information

Challenges and Recent Advances in NK Cell-Targeted Immunotherapies in Solid Tumors by Lian, Guangyu, Mak, Thomas Shiu-Kwong, Yu, Xueqing, Lan, Hui-Yao

“…Natural killer (NK) cell is a powerful malignant cells killer, providing rapid immune responses via direct cytotoxicity without the need of antigen processing…”
Get full text

ASO Author Reflections: α-Fetoprotein in Early-Stage Hepatocellular Carcinoma (BCLC Stage 0/A): Beyond Diagnosis to Prognostication by Yao, Lan-Qing, Lv, Guo-Yue, Yang, Tian

Get full text

Combination of Asiatic Acid and Naringenin Modulates NK Cell Anti-cancer Immunity by Rebalancing Smad3/Smad7 Signaling by Lian, Guang-Yu, Wang, Qing-Ming, Tang, Patrick Ming-Kuen, Zhou, Shuang, Huang, Xiao-Ru, Lan, Hui-Yao

“…Transforming growth factor β1 (TGF-β1) plays a promoting role in tumor growth via a mechanism associated with hyperactive Smad3 and suppressed Smad7 signaling…”
Get full text

Diverse roles of TGF-β/Smads in renal fibrosis and inflammation by Lan, Hui Yao

“…TGF-β1 has been long considered as a key mediator in renal fibrosis and induces renal scarring largely by activating its downstream Smad signaling pathway…”
Get full text

Macrophage Migration Inhibitory Factor (MIF) as a Stress Molecule in Renal Inflammation by Kong, Yao-Zhong, Chen, Qiyan, Lan, Hui-Yao

“…Renal inflammation is an initial pathological process during progressive renal injury regardless of the initial cause. Macrophage migration inhibitory factor…”
Get full text

Group lying with negative externality by Yao, Lan, Zhou, Chong

“…We use a modified die‐rolling experiment to study whether negative externality affects a group's decisions about whether to cheat. Our results show that group…”
Get full text

A New Therapeutic Trend: Natural Medicine for Ameliorating Ischemic Stroke via PI3K/Akt Signaling Pathway by Liu, Xian, Xiao, Xinyu, Han, Xue, Yao, Lan, Lan, Wei

“…Ischemic stroke (IS) is an acute cerebrovascular disease caused by sudden arterial occlusion, which is characterized by a high morbidity, mortality, and…”
Get full text

Transforming growth factor‐β signalling in renal fibrosis: from Smads to non‐coding RNAs by Tang, Patrick Ming‐Kuen, Zhang, Ying‐Ying, Mak, Thomas Shiu‐Kwong, Tang, Philip Chiu‐Tsun, Huang, Xiao‐Ru, Lan, Hui‐Yao

“…Transforming growth factor‐β (TGF‐β) is the key player in tissue fibrosis. However, antifibrotic therapy targeting this multifunctional protein may interfere…”
Get full text