Search Results - "Yao, Zhengju"

Foxp1 controls brown/beige adipocyte differentiation and thermogenesis through regulating β3-AR desensitization by Liu, Pei, Huang, Sixia, Ling, Shifeng, Xu, Shuqin, Wang, Fuhua, Zhang, Wei, Zhou, Rujiang, He, Lin, Xia, Xuechun, Yao, Zhengju, Fan, Ying, Wang, Niansong, Hu, Congxia, Zhao, Xiaodong, Tucker, Haley O., Wang, Jiqiu, Guo, Xizhi

“…β-Adrenergic receptor (β-AR) signaling is a pathway controlling adaptive thermogenesis in brown or beige adipocytes. Here we investigate the biological roles…”
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Nonredundant roles for Stat5a/b in directly regulating Foxp3 by Yao, Zhengju, Kanno, Yuka, Kerenyi, Marc, Stephens, Geoffrey, Durant, Lydia, Watford, Wendy T., Laurence, Arian, Robinson, Gertraud W., Shevach, Ethan M., Moriggl, Richard, Hennighausen, Lothar, Wu, Changyou, O'Shea, John J.

“…Stats (signal transducers and activators of transcription) regulate multiple aspects of T-cell fate. T regulatory (Treg) cells are a critical subset that…”
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Identification of the E3 Deubiquitinase Ubiquitin-specific Peptidase 21 (USP21) as a Positive Regulator of the Transcription Factor GATA3 by Zhang, Jing, Chen, Chen, Hou, Xiaoxia, Gao, Yayi, Lin, Fang, Yang, Jing, Gao, Zhimei, Pan, Lina, Tao, Lianqin, Wen, Chijun, Yao, Zhengju, Tsun, Andy, Shi, Guochao, Li, Bin

“…The expression of the transcription factor GATA3 in FOXP3+ regulatory T (Treg) cells is crucial for their physiological function in limiting inflammatory…”
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FOXP3 and RORγt: Transcriptional regulation of Treg and Th17 by Chen, Zuojia, Lin, Fang, Gao, Yayi, Li, Zhiyuan, Zhang, Jing, Xing, Yue, Deng, Zihou, Yao, Zhengju, Tsun, Andy, Li, Bin

“…FOXP3 +CD4 +CD25 + Regulatory T (Treg) cells and IL-17 producing helper T cells (Th17) are critical subsets of T cells which play essential roles in immune…”
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Deacetylation of FOXP1 by HDAC7 potentiates self-renewal of mesenchymal stem cells by Ling, Shifeng, Chen, Tienan, Wang, Shaojiao, Zhang, Wei, Zhou, Rujiang, Xia, Xuechun, Yao, Zhengju, Fan, Ying, Ning, Song, Liu, Jiayin, Qin, Lianju, Tucker, Haley O, Wang, Niansong, Guo, Xizhi

“…Mesenchymal stem cells (MSCs) are widely used in a variety of tissue regeneration and clinical trials due to their multiple differentiation potency. However,…”
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Stat5a/b Are Essential for Normal Lymphoid Development and Differentiation by Yao, Zhengju, Cui, Yongzhi, Watford, Wendy T., Bream, Jay H., Yamaoka, Kunihiro, Hissong, Bruce D., Li, Denise, Durum, Scott K., Jiang, Qiong, Bhandoola, Avinash, Hennighausen, Lothar, O'Shea, John J.

“…Cytokines that use the common gamma chain γc are critical for lymphoid development and function. Mutations of the IL-7 receptor, γc, or its associated kinase,…”
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Osteoblastic Wnts differentially regulate bone remodeling and the maintenance of bone marrow mesenchymal stem cells by Wan, Yong, Lu, Cheng, Cao, Jingjing, Zhou, Rujiang, Yao, Yiyun, Yu, Jian, Zhang, Lingling, Zhao, Haixia, Li, Hanjun, Zhao, Jianzhi, Zhu, Xuming, He, Lin, Liu, Yongzhong, Yao, Zhengju, Yang, Xiao, Guo, Xizhi

“…Abstract Wnt signaling has important roles in embryonic bone development and postnatal bone remodeling, but inconsistent impact on bone property is observed in…”
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Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress during Hair Cycling by Zhao, Jianzhi, Li, Hanjun, Zhou, Rujiang, Ma, Gang, Dekker, Joseph D, Tucker, Haley O, Yao, Zhengju, Guo, Xizhi

“…Hair follicle stem cells (HFSCs) in the bugle circularly generate outer root sheath (ORS) through linear proliferation within limited cycles during anagen…”
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Wnt-mediated reciprocal regulation between cartilage and bone development during endochondral ossification by Lu, Cheng, Wan, Yong, Cao, Jingjing, Zhu, Xuming, Yu, Jian, Zhou, Rujiang, Yao, Yiyun, Zhang, Lingling, Zhao, Haixia, Li, Hanjun, Zhao, Jianzhi, He, Lin, Ma, Gang, Yang, Xiao, Yao, Zhengju, Guo, Xizhi

“…Abstract The role of Wnt signaling is extensively studied in skeletal development and postnatal bone remodeling, mostly based on the genetic approaches of…”
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Misexpression of Pknox2 in mouse limb bud mesenchyme perturbs zeugopod development and deltoid crest formation by Zhou, Wenrong, Zhu, Huang, Zhao, Jianzhi, Li, Hanjun, Wan, Yong, Cao, Jingjing, Zhao, Haixia, Yu, Jian, Zhou, Rujiang, Yao, Yiyun, Zhang, Lingling, Wang, Lifang, He, Lin, Ma, Gang, Yao, Zhengju, Guo, Xizhi

“…The TALE (Three Amino acid Loop Extension) family consisting of Meis, Pbx and Pknox proteins is a group of transcriptional co-factors with atypical…”
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Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4 + T Cells by Wei, Gang, Wei, Lai, Zhu, Jinfang, Zang, Chongzhi, Hu-Li, Jane, Yao, Zhengju, Cui, Kairong, Kanno, Yuka, Roh, Tae-Young, Watford, Wendy T., Schones, Dustin E., Peng, Weiqun, Sun, Hong-wei, Paul, William E., O'Shea, John J., Zhao, Keji

“…Multipotential naive CD4 + T cells differentiate into distinct lineages including T helper 1 (Th1), Th2, Th17, and inducible T regulatory (iTreg) cells. The…”
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FOXP4 differentially controls cold-induced beige adipocyte differentiation and thermogenesis by Wang, Fuhua, Xu, Shuqin, Chen, Tienan, Ling, Shifeng, Zhang, Wei, Wang, Shaojiao, Zhou, Rujiang, Xia, Xuechun, Yao, Zhengju, Li, Pengxiao, Zhao, Xiaodong, Wang, Jiqiu, Guo, Xizhi

“…Beige adipocytes have a discrete developmental origin and possess notable plasticity in their thermogenic capacity in response to various environmental cues,…”
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The Ubiquitin Ligase Stub1 Negatively Modulates Regulatory T Cell Suppressive Activity by Promoting Degradation of the Transcription Factor Foxp3 by Chen, Zuojia, Barbi, Joseph, Bu, Shurui, Yang, Huang-Yu, Li, Zhiyuan, Gao, Yayi, Jinasena, Dilini, Fu, Juan, Lin, Fang, Chen, Chen, Zhang, Jing, Yu, Ning, Li, Xiangpei, Shan, Zhao, Nie, Jia, Gao, Zhimei, Tian, Hong, Li, Yangyang, Yao, Zhengju, Zheng, Ying, Park, Benjamin V., Pan, Ziyi, Zhang, Jing, Dang, Eric, Li, Zhiguang, Wang, Honglin, Luo, Weibo, Li, Liwu, Semenza, Gregg L., Zheng, Song-Guo, Loser, Karin, Tsun, Andy, Greene, Mark I., Pardoll, Drew M., Pan, Fan, Li, Bin

“…Regulatory T (Treg) cells suppress inflammatory immune responses and autoimmunity caused by self-reactive T cells. The key Treg cell transcription factor Foxp3…”
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Correction: FOXP4 differentially controls cold-induced beige adipocyte differentiation and thermogenesis by Wang, Fuhua, Xu, Shuqin, Chen, Tienan, Ling, Shifeng, Zhang, Wei, Wang, Shaojiao, Zhou, Rujiang, Xia, Xuechun, Yao, Zhengju, Li, Pengxiao, Zhao, Xiaodong, Wang, Jiqiu, Guo, Xizhi

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Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation by Laurence, Arian, Tato, Cristina M., Davidson, Todd S., Kanno, Yuka, Chen, Zhi, Yao, Zhengju, Blank, Rebecca B., Meylan, Françoise, Siegel, Richard, Hennighausen, Lothar, Shevach, Ethan M., O'Shea, John J.

“…Recent work has identified a new subset of effector T cells that produces interleukin (IL)-17 known as T helper 17 (Th17) cells, which is involved in the…”
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Foxp2 regulates anatomical features that may be relevant for vocal behaviors and bipedal locomotion by Xu, Shuqin, Liu, Pei, Chen, Yuanxing, Chen, Yi, Zhang, Wei, Zhao, Haixia, Cao, Yiwei, Wang, Fuhua, Jiang, Nana, Lin, Shifeng, Li, Baojie, Zhang, Zhenlin, Wei, Zhanying, Fan, Ying, Jin, Yunyun, He, Lin, Zhou, Rujiang, Dekker, Joseph D., Tucker, Haley O., Fisher, Simon E., Yao, Zhengju, Liu, Quansheng, Xia, Xuechun, Guo, Xizhi

“…Fundamental human traits, such as language and bipedalism, are associated with a range of anatomical adaptations in craniofacial shaping and skeletal…”
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Forkhead box P1 (Foxp1) in osteoblasts regulates bone mass accrual and adipose tissue energy metabolism by Zhang, Wei, Liu, Pei, Ling, Shifeng, Wang, Fuhua, Wang, Shaojiao, Chen, Tienan, Zhou, Rujiang, Xia, Xuechun, Yao, Zhengju, Fan, Ying, Wang, Niansong, Wang, Jiqiu, Tucker, Haley O., Guo, Xizhi

“…ABSTRACT Adiponectin (AdipoQ), a hormone abundantly secreted by adipose tissues, has multiple beneficial functions, including insulin sensitization as well as…”
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Ablation of Wntless in endosteal niches impairs lymphopoiesis rather than HSCs maintenance by Cao, Jingjing, Zhang, Lingling, Wan, Yong, Li, Hanjun, Zhou, Rujiang, Ding, Heyuan, Liu, Yongzhong, Yao, Zhengju, Guo, Xizhi

“…Osteoblasts and perivascular stromal cells constitute essential niches for HSC self‐renewal and maintenance in the bone marrow. Wnt signaling is important to…”
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Foxp1/2/4 regulate endochondral ossification as a suppresser complex by Zhao, Haixia, Zhou, Wenrong, Yao, Zhengju, Wan, Yong, Cao, Jingjing, Zhang, Lingling, Zhao, Jianzhi, Li, Hanjun, Zhou, Rujiang, Li, Baojie, Wei, Gang, Zhang, Zhenlin, French, Catherine A., Dekker, Joseph D., Yang, Yingzi, Fisher, Simon E., Tucker, Haley O., Guo, Xizhi

“…Osteoblast induction and differentiation in developing long bones is dynamically controlled by the opposing action of transcriptional activators and…”
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Bone marrow fibrosis with fibrocytic and immunoregulatory responses induced by β-catenin activation in osteoprogenitors by Yu, Jian, Cao, Jingjing, Li, Hanjun, Liu, Pei, Xu, Shuqin, Zhou, Rujiang, Yao, Zhengju, Guo, Xizhi

“…Abstract Wnt/β-catenin signaling has been reported to contribute to the development of bone fibrous dysplasia. However, it remains unclear whether fibrocytes…”
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