Search Results - "Yao, Meilian"
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Reprogramming the myocardial infarction microenvironment with melanin-based composite nanomedicines in mice
Published in Nature communications (06-08-2024)“…Myocardial infarction (MI) has a 5-year mortality rate of more than 50% due to the lack of effective treatments. Interactions between cardiomyocytes and the MI…”
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The TRPM7 channel reprograms cellular glycolysis to drive tumorigenesis and angiogenesis
Published in Cell death & disease (06-03-2023)“…Cancer or endothelial cells preferably catabolize glucose through aerobic glycolysis rather than oxidative phosphorylation. Intracellular ionic signaling has…”
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FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
Published in Cell reports (Cambridge) (28-03-2023)“…PI3K regulatory subunit p85s normally stabilizes and regulates catalytic subunit p110s in the cytoplasm. Recent studies show that p110-free p85s in the nucleus…”
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Hypoxia-induced cysteine metabolism reprogramming is crucial for the tumorigenesis of colorectal cancer
Published in Redox biology (01-09-2024)“…Metabolic reprogramming is a hallmark of human cancer, and cancer-specific metabolism provides opportunities for cancer diagnosis, prognosis, and treatment…”
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Peroxynitrite-Free Nitric Oxide-Embedded Nanoparticles Maintain Nitric Oxide Homeostasis for Effective Revascularization of Myocardial Infarcts
Published in ACS nano (26-11-2024)“…Revascularization is crucial for treating myocardial infarction (MI). Nitric oxide (NO), at an appropriate concentration, is recognized as an ideal and potent…”
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Inhibition of MCF-7 breast cancer cell proliferation by a synthetic peptide derived from the C-terminal sequence of Orai channel
Published in Biochemical and biophysical research communications (03-09-2019)“…Intracellular Ca2+ signals play many important cellular functions such as migration, proliferation and differentiation. Store-operated Ca2+ entry (SOCE) is a…”
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