Search Results - "Yao, Jorge"
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1
Expression of androgen and oestrogen receptors and its prognostic significance in urothelial neoplasm of the urinary bladder
Published in BJU international (01-06-2012)“…What's known on the subject? and What does the study add? Steroid hormone receptor signals have been implicated in bladder tumourigenesis and tumour…”
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2
Dihydrotestosterone upregulates the expression of epidermal growth factor receptor and ERBB2 in androgen receptor-positive bladder cancer cells
Published in Endocrine-related cancer (01-08-2011)“…Androgen receptor (AR) signals play important roles in bladder carcinogenesis and tumor progression. Activation of the epidermal growth factor receptor (EGFR)…”
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3
ERG–TMPRSS2 rearrangement is shared by concurrent prostatic adenocarcinoma and prostatic small cell carcinoma and absent in small cell carcinoma of the urinary bladder: evidence supporting monoclonal origin
Published in Modern pathology (01-08-2011)“…Prostatic carcinoma is a heterogeneous disease with frequent multifocality and variability in morphology. Particularly, prostatic small cell carcinoma is a…”
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4
Androgen receptor is a tumor suppressor and proliferator in prostate cancer
Published in Proceedings of the National Academy of Sciences - PNAS (26-08-2008)“…Targeting androgens/androgen receptor (AR) functions via androgen deprivation therapy (ADT) remains the standard treatment for prostate cancer. However, most…”
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5
Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway
Published in Endocrine-related cancer (01-06-2012)“…Small cell neuroendocrine carcinoma (SCNC) of the prostate is a variant form of prostate cancer that occurs de novo or as a recurrent tumor in patients who…”
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6
Frozen section assessment in testicular and paratesticular lesions suspicious for malignancy: its role in preventing unnecessary orchiectomy
Published in Human pathology (01-09-2012)“…Summary To investigate the role of frozen section assessment in sparing unnecessary orchiectomy for suspected lesions, we retrospectively reviewed…”
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7
GATA binding protein 3 is down-regulated in bladder cancer yet strong expression is an independent predictor of poor prognosis in invasive tumor
Published in Human pathology (01-11-2012)“…Summary Although GATA binding protein 3 , a zinc finger transcription factor and an estrogen receptor–regulated gene, has recently been suggested as a marker…”
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8
Predominantly cystic clear cell renal cell carcinoma and multilocular cystic renal neoplasm of low malignant potential form a low-grade spectrum
Published in Virchows Archiv : an international journal of pathology (01-07-2018)“…Multilocular cystic renal cell carcinoma has been recently excluded from clear cell renal cell carcinoma (CCRCC) category and re-designated as multilocular…”
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9
Combination of napsin A and TTF-1 immunohistochemistry helps in differentiating primary lung adenocarcinoma from metastatic carcinoma in the lung
Published in Applied immunohistochemistry & molecular morphology (01-07-2011)“…Differentiation of primary from metastatic adenocarcinoma in the lung can be challenging, and it demands sensitive and specific biomarkers, especially when the…”
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10
Expression of UDP-glucuronosyltransferase 1A in bladder cancer: Association with prognosis and regulation by estrogen
Published in Molecular carcinogenesis (01-04-2014)“…Although UDP‐glucuronosyltransferase 1A (UGT1A) plays an important role in preventing bladder cancer initiation by detoxifying carcinogenic compounds, its…”
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11
Frequent TMPRSS2-ERG rearrangement in prostatic small cell carcinoma detected by fluorescence in situ hybridization: the superiority of fluorescence in situ hybridization over ERG immunohistochemistry
Published in Human pathology (01-10-2013)“…Summary Small cell carcinoma of the prostate is both morphologically and immunohistochemically similar to small cell carcinoma of other organs such as the…”
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12
Multispectral Photoacoustic Imaging of Prostate Cancer: Preliminary Ex-vivo Results
Published in Journal of clinical imaging science (2013)“…The objective of this study is to validate if ex-vivo multispectral photoacoustic (PA) imaging can differentiate between malignant prostate tissue, benign…”
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13
Increased androgen receptor gene copy number is associated with TMPRSS2-ERG rearrangement in prostatic small cell carcinoma
Published in Molecular carcinogenesis (01-09-2015)“…Small cell carcinoma of the prostate (PSCC) is a highly aggressive malignancy that often develops in patients previously treated with hormonal therapy for…”
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14
Immunohistochemical Analysis in a Morphologic Spectrum of Urachal Epithelial Neoplasms: Diagnostic Implications and Pitfalls
Published in The American journal of surgical pathology (01-06-2011)“…The vast majority of urachal epithelial neoplasms are adenocarcinomas with several described morphologic subtypes that include both enteric and nonenteric…”
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15
Small cell carcinoma of the prostate : An immunohistochemical study
Published in The American journal of surgical pathology (01-06-2006)“…Small cell carcinoma of the prostate (SCPC) is morphologically similar to small cell carcinoma of the lung (SCLC) and maybe misinterpreted as Gleason pattern…”
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16
Seminal plasma proteins in prostatic carcinoma: increased nuclear semenogelin I expression is a predictor of biochemical recurrence after radical prostatectomy
Published in Human pathology (01-11-2012)“…Summary Semenogelins and eppin are seminal plasma proteins that form a complex and inhibit sperm motility. However, the role of these proteins in prostate…”
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17
Transgelin Functions as a Suppressor via Inhibition of ARA54-Enhanced Androgen Receptor Transactivation and Prostate Cancer Cell Growth
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2007)“…The androgen receptor (AR) requires coregulators for its optimal function. However, whether AR coregulators further need interacting protein(s) for their…”
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18
Identifying additional lymph nodes in radical cystectomy lymphadenectomy specimens
Published in Modern pathology (01-01-2012)“…Lymph node count has prognostic implications in bladder cancer patients who are treated with radical cystectomy. Lymph nodes that are too small to identify…”
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19
CD44 expression is a feature of prostatic small cell Carcinoma and Distinguishes it from its Mimickers
Published in Human pathology (01-02-2009)“…Summary Small cell neuroendocrine carcinoma of the prostate is a rare variant of prostatic cancer that shares morphologic similarity with prostatic…”
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20
Loss of BRCA2 promotes prostate cancer cell invasion through up‐regulation of matrix metalloproteinase‐9
Published in Cancer science (01-03-2008)“…BRCA2 is a multifunctional tumor suppressor protein which plays critical roles in DNA repair, transcription, and cell proliferation, and the loss of which has…”
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