Search Results - "Yao, J J A"

The prioritisation of paediatrics and palliative care in cancer control plans in Africa by Weaver, M S, Yao, A J J, Renner, L A, Harif, M, Lam, C G

“…Background: Given the burden of childhood cancer and palliative care need in Africa, this paper investigated the paediatric and palliative care elements in…”
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Reverse use dependence of Kv4.2 blockade by 4-aminopyridine by Tseng, G N, Jiang, M, Yao, J A

“…4-Aminopyridine (4AP) can block various K channels with different state dependences; block occurs in the activated state or in the closed state. The use of K…”
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Integrating a palliative approach into the healthcare provided by the French-African Pediatric Oncology Group's pilot units. Insights from a 3-year training program by Edan, C., Yao, A.J.J., Hessissen, L., Moreira, C., Viallard, M.L., Poulain, P., Calmanti, S., Thinlot, C., Aubier, F., Douçot, M.S., Gagnepain-Lacheteau, A., Patte, C.

“…Working alongside local stakeholders, members of the French-African Pediatric Oncology Group developed a 3-year program to train pediatric oncology teams from…”
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Azimilide (NE-10064) can prolong or shorten the action potential duration in canine ventricular myocytes: dependence on blockade of K, Ca, and Na channels by Yao, J A, Tseng, G N

“…Azimilide (NE-10064) has antiarrhythmic and antifibrillatory effects in canine models of ventricular arrhythmia. The goal of the present study was to examine…”
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Quinidine preferentially blocks the slow delayed rectifier potassium channel in the rested state by Yao, J A, Trybulski, E J, Tseng, G N

“…We examined the effects of quinidine on a slow delayed rectifier K current induced by a human IsK cDNA (hlsK) in Xenopus oocytes. The apparent blocking potency…”
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Quinidine enhances and suppresses Kv1.2 from outside and inside the cell, respectively by Tseng, G N, Zhu, B, Ling, S, Yao, J A

“…We studied the effects of quinidine on two K channel clones expressed in Xenopus oocytes, Kv1.2 and Kv1.4. Quinidine had an agonist (enhancement) and a blocker…”
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Mechanism of enhancement of slow delayed rectifier current by extracellular sulfhydryl modification by Yao, J A, Jiang, M, Tseng, G N

“…To explore the role of sulfhydryl (SH) groups in the function of cardiac slow delayed rectifier channels, we tested the effects of extracellular thimerosal…”
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Modulation of 4-AP block of a mammalian A-type K channel clone by channel gating and membrane voltage by Yao, J.A., Tseng, G.N.

“…We examined the state-, voltage-, and time dependences of interaction between 4-AP and a mammalian A-type K channel clone (rKv1.4) expressed in Xenopus oocytes…”
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Modulation of K channels by coexpressed human alpha1C-adrenoceptor in Xenopus oocytes by Tseng, G N, Yao, J A, Tseng-Crank, J

“…alpha1-Adrenoceptors participate in the regulation of inotropy and chronotropy in the heart. Modulation of cardiac K-channel function plays an important role…”
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Functional role of the NH2-terminal cytoplasmic domain of a mammalian A-type K channel by TSENG-CRANK, J, JIAN-AN YAO, BERMAN, M. F, GEA-NY TSENG

“…It has been shown for a Shaker channel (H-4) that its NH2-terminal cytoplasmic domain may form a "ball and chain" structure, with the "chain" tethering the…”
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Remodeling of Gap Junctional Channel Function in Epicardial Border Zone of Healing Canine Infarcts by Yao, Jian-An, Hussain, Wajid, Patel, Pravina, Peters, Nicholas S, Boyden, Penelope A, Wit, Andrew L

“…ABSTRACT—The epicardial border zone (EBZ) of canine infarcts has increased anisotropy because of transverse conduction slowing. It remains unknown whether…”
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Childhood cancer in Côte d'Ivoire, 1995 - 2004: challenges and hopes by Yao, J J A, Couitchere, L, Atimere, Y, Koné, D, Azagoh-Kouadio, R, Oulai, M S, Stefan, D C

“…There is insufficient research into the state of paediatric oncology in African countries. The purpose of this study was to analyse the state of paediatric…”
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Effects of n-dodecylguanidine on A-type potassium channels: role of external surface charges in channel gating by Yao, J A, Saxena, N C, Ziai, M R, Ling, S, Tseng, G N

“…n-Dodecylguanidine (C12-G) is an amphipathic compound with a guanidine moiety, which is positively charged at physiological pH, and a hydrophobic side chain…”
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Cell Coupling Between Ventricular Myocyte Pairs From Connexin43-Deficient Murine Hearts by Yao, Jian-An, Gutstein, David E, Liu, Fangyu, Fishman, Glenn I, Wit, Andrew L

“…ABSTRACT—Mice with cardiac-restricted inactivation of the connexin43 gene (CKO mice) have moderate slowing of ventricular conduction and lethal arrhythmias…”
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Heterogeneous changes in K currents in rat ventricles three days after myocardial infarction by Yao, J A, Jiang, M, Fan, J S, Zhou, Y Y, Tseng, G N

“…After coronary artery occlusion, surviving myocardium in and around the infarct zone plays an important role in arrhythmogenesis. Understanding the mechanisms…”
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Differential effects of S6 mutations on binding of quinidine and 4-aminopyridine to rat isoform of Kv1.4: common site but different factors in determining blockers' binding affinity by Zhang, H, Zhu, B, Yao, J A, Tseng, G N

“…Quinidine and 4AP are two nonspecific K channel blockers. Both block voltage-gated K channels from the intracellular side of the membrane and, in most cases,…”
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Role of tyrosine kinase activity in cardiac slow delayed rectifier channel modulation by cell swelling by Zhou, Y Y, Yao, J A, Tseng, G N

“…We studied the effects of cell swelling on membrane currents of canine ventricular myocytes using the whole-cell patch-clamp method. Cell swelling was induced…”
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Anti-arrhythmic mechanisms of sophoramine by Yao, J A, Zhang, B H

“…Sophoramine (SA) exerted an inhibitory effect on arrhythmias in rats induced by aconitine and coronary artery ligation, and elevated the ventricular…”
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Graphene-integrated toroidal resonance metasurfaces used for picogram-level detection of chlorothalonil in the terahertz region by Yang, Maosheng, Yao, Haiyun, Lu, Yuying, Li, Peipei, Du, Binbin, Ma, Qilin, Liu, Dandan, Zhang, Tan, Fang, Jie, Wang, Tongling, Yan, Xin, Zhang, Gang, Liang, Lanju, Yang, Qilin, Wang, Yaru, Wang, Meng, Dai, Zijie, Zhang, Jingjing, Ye, Yunxia, Song, Xiaoxian, Zhang, Haiting, Ren, Xundong, Yao, Jianquan

“…Toroidal dipole resonance can significantly reduce radiation loss of materials, potentially improving sensor sensitivity. Generally, toroidal dipole response…”
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Laboratory selection for spirodiclofen resistance and cross-resistance in Panonychus citri by De Yi, Yu, Chang Fang, Wang, Yun, Yu, Yu Qing, Huang, Jin Ai, Yao, Jin Feng, Hu

“…Selection for spirodiclofen resistance was done in the laboratory with a susceptible strain of the citrus red mite, Panonychus citri (McGregor). Successive…”
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