Search Results - "Yao, Hang"
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Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection
Published in Nature communications (18-02-2020)“…Oxidative stress is a major pathogenic mechanism in Parkinson’s disease (PD). As an important cellular antioxidant, glutathione (GSH) balances the production…”
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2
Effects of two antioxidants with different degrees of steric hindrance on the thermal‐oxidative aging properties of ABS resin
Published in Journal of applied polymer science (10-05-2024)“…ABS resin is easily oxidized and deteriorated during use or processing. The addition of antioxidants is an effective method for improving ABS oxidation. The…”
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3
MSP–RON signalling in cancer: pathogenesis and therapeutic potential
Published in Nature reviews. Cancer (01-07-2013)“…Key Points Macrophage-stimulating protein (MSP; also known as MST1 and hepatocye growth factor-like (HGFL)), is a serum-derived growth factor that activates…”
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4
Synthesis of the reactive hindered phenol antioxidant 3,5‐di‐tert‐butyl‐4‐hydroxyphenyl methyl isobutylene ester and its application in ABS resin
Published in Journal of applied polymer science (10-08-2023)“…In this study, a reactive hindered phenol antioxidant, 3,5‐di‐tert‐butyl‐4‐hydroxyphenyl methyl isobutylene ester (DBHMIE), was synthesized and used to improve…”
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5
Duocarmycin-based antibody–drug conjugates as an emerging biotherapeutic entity for targeted cancer therapy: Pharmaceutical strategy and clinical progress
Published in Drug discovery today (01-08-2021)“…•Duocarmycins and analogues are DNA-alkylators highly cytotoxic to cancer cells.•Up to now, none of duocarmycins have not been approved for oncological…”
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Progress and challenge in development of biotherapeutics targeting MET receptor for treatment of advanced cancer
Published in Biochimica et biophysica acta. Reviews on cancer (01-12-2020)“…Advanced epithelial cancers such as gastric, lung, and pancreatic tumors are featured by invasive proliferation, distant metastasis, acquired chemoresistance,…”
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Effect of Plasticization on Stretching Stability of Poly(Vinyl Alcohol) Films: A Case Study Using Glycerol and Water
Published in Macromolecular rapid communications. (01-01-2023)“…Adding small molecular plasticizers is the most common route to tailor the stretchability of poly(vinyl alcohol) (PVA). However, how the plasticization along…”
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8
Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice
Published in Cell reports (Cambridge) (25-10-2022)“…The function and regulation of different heterogeneous reactive states of astrocytes in depression remain unclear. Here, we demonstrate that neurotoxic…”
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Comparison of RFE-DL and stacking ensemble learning algorithms for classifying mangrove species on UAV multispectral images
Published in International journal of applied earth observation and geoinformation (01-08-2022)“…•Classification of mangrove species using the UAV multispectral image and DSM.•RFE-based variable selection improves classification performance of DL…”
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10
Novel Hybrid LLC Resonant and DAB Linear DC–DC Converter: Average Model and Experimental Verification
Published in IEEE transactions on industrial electronics (1982) (01-09-2017)“…A novel hybrid LLC resonant and dual active bridge (DAB) linear dc-dc converter is proposed as bus converter, which can achieve soft switching and constant…”
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11
Fabrication of methyl acrylate modified silica aerogel for capture of Cu2+ from aqueous solutions
Published in Journal of sol-gel science and technology (01-05-2021)“…With SiO 2 gel as the main skeleton material, the surface modification with methyl acrylate (MA) and tetraethylenepentamine (TEPA) was carried out by Michael…”
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12
Development of a multi‐recombinase polymerase amplification assay for rapid identification of COVID‐19, influenza A and B
Published in Journal of medical virology (01-01-2023)“…The coronavirus disease 2019 (COVID‐19) pandemic caused extensive loss of life worldwide. Further, the COVID‐19 and influenza mix‐infection had caused great…”
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13
RON receptor tyrosine kinase in pancreatic ductal adenocarcinoma: Pathogenic mechanism in malignancy and pharmaceutical target for therapy
Published in Biochimica et biophysica acta. Reviews on cancer (01-04-2020)“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with poor prognosis and high mortality. Molecular aberrations associated with…”
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14
Histone acetyltransferase p300/CBP inhibitor C646 blocks the survival and invasion pathways of gastric cancer cell lines
Published in International journal of oncology (01-12-2017)“…The histone acetyltransferases (HATs) adenovirus E1A-associated protein (p300) and CREB binding protein (CBP) serve as coactivators during a diverse assortment…”
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15
Pharmaceutical strategies in the emerging era of antibody-based biotherapeutics for the treatment of cancers overexpressing MET receptor tyrosine kinase
Published in Drug discovery today (01-01-2021)“…•Cancerous MET overexpression is a common pathological feature manifested by genetic, molecular, and cellular abnormalities.•Conventional therapeutic…”
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16
Selective Recognition of 2,4,6-Trichlorophenol by Molecularly Imprinted Polymers Based on Magnetic Halloysite Nanotubes Composites
Published in Journal of physical chemistry. C (07-04-2011)“…Magnetic nanoparticles were attached to carboxylic acid functionalized halloysite nanotubes (HNTs−COOH) by high-temperature reaction of ferric…”
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17
Antibody–drug conjugates targeting RON receptor tyrosine kinase as a novel strategy for treatment of triple-negative breast cancer
Published in Drug discovery today (01-07-2020)“…•Aberrant RON expression is a pathogenic feature in breast cancer including TNBC.•Antibody-drug conjugates targeting RON for TNBC therapy is a novel…”
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18
Precise control and prediction of the greenhouse growth environment of Dendrobium candidum
Published in Computers and electronics in agriculture (01-08-2018)“…•A system for precise control and prediction of a greenhouse environment was constructed to realize real-time monitoring and intelligent control of soil…”
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19
Biomimetic cartilage-lubricating polymers regenerate cartilage in rats with early osteoarthritis
Published in Nature biomedical engineering (01-10-2021)“…The early stages of progressive degeneration of cartilage in articular joints are a hallmark of osteoarthritis. Healthy cartilage is lubricated by brush-like…”
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20
Assessing causal relationships between gut microbiota and abortion: evidence from two sample Mendelian randomization analysis
Published in Frontiers in endocrinology (Lausanne) (10-07-2024)“…While some studies have suggested a link between gut microbiota (GM) and abortion, the causal relationship remains unclear. To explore the causal relationship…”
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