Search Results - "Yano, Takahisa"

An Alternative Method for Generating Arynes from ortho-Silylaryl Triflates: Activation by Cesium Carbonate in the Presence of a Crown Ether by Yoshida, Suguru, Hazama, Yuki, Sumida, Yuto, Yano, Takahisa, Hosoya, Takamitsu

“…An alternative method for generating arynes from ortho-silylaryl triflates using cesium carbonate and 18-crown-6 is reported. The method was efficiently…”
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Pharmacodynamic Evaluation of Ampicillin-sulbactam in Pediatric Patients Using Plasma and Urine Data by Onita, Tetsushu, Ikawa, Kazuro, Ishihara, Noriyuki, Tamaki, Hiroki, Yano, Takahisa, Naora, Kohji, Morikawa, Norifumi

“…We aimed to develop population pharmacokinetic (PK) models of ampicillin and sulbactam using pooled data analysis and to optimize dosing regimens of…”
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Inpatient Expenditures Attributable to Hospital-Onset Clostridium difficile Infection: A Nationwide Case–Control Study in Japan by Fukuda, Haruhisa, Yano, Takahisa, Shimono, Nobuyuki

“…Background Hospital-onset Clostridium difficile infections (CDIs) have a considerable clinical and economic impact on patients and payers. Quantifying the…”
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Prostatic Pharmacokinetic/Pharmacodynamic Evaluation of Ampicillin‐Sulbactam for Bacterial Prostatitis and Preoperative Prophylaxis by Onita, Tetsushu, Ikawa, Kazuro, Nakamura, Kogenta, Nishikawa, Genya, Kobayashi, Ikuo, Ishihara, Noriyuki, Tamaki, Hiroki, Yano, Takahisa, Naora, Kohji, Morikawa, Norifumi

“…This study aims to define the penetration of ampicillin and sulbactam into prostate tissue, develop a prostatic pharmacokinetic model of each drug, and assess…”
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Pharmacokinetic and pharmacodynamic simulation for the quantitative risk assessment of linezolid‐associated thrombocytopenia by Onita, Tetsushu, Ishihara, Noriyuki, Ikebuchi, Amika, Yano, Takahisa, Nishimura, Nobuhiro, Tamaki, Hiroki, Ikawa, Kazuro, Morikawa, Norifumi, Naora, Kohji

“…What Is Known and Objective Linezolid (LZD) may cause thrombocytopenia, which can result in discontinuation of treatment. In this study, the blood LZD trough…”
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L Type Ca2+ Channel Blockers Prevent Oxaliplatin-Induced Cold Hyperalgesia and TRPM8 Overexpression in Rats by Kawashiri, Takehiro, Egashira, Nobuaki, Kurobe, Kentaro, Tsutsumi, Kuniaki, Yamashita, Yuji, Ushio, Soichiro, Yano, Takahisa, Oishi, Ryozo

“…Background: Oxaliplatin is an important drug used in the treatment of colorectal cancer. However, it frequently causes severe acute and chronic peripheral…”
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Role of oxidative stress in vinorelbine-induced vascular endothelial cell injury by Yamada, Takaaki, Egashira, Nobuaki, Imuta, Maiko, Yano, Takahisa, Yamauchi, Yui, Watanabe, Hiroyuki, Oishi, Ryozo

“…Vinorelbine (VNR), a vinca alkaloid anticancer drug, often causes vascular injury such as venous irritation, vascular pain, phlebitis, and necrotizing…”
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A diet high in glucose and deficient in dietary fibre causes fat accumulation in the liver without weight gain by Karino, Sonoko, Usuda, Haruki, Kanda, Shoma, Okamoto, Takayuki, Niibayashi, Tomomi, Yano, Takahisa, Naora, Kohji, Wada, Koichiro

“…This study investigated whether a standard calorie diet that is high in glucose and deficient in dietary fibre (described as HGD [high glucose diet]) induces…”
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Pulmonary Pharmacokinetic and Pharmacodynamic Evaluation of Ampicillin/Sulbactam Regimens for Pneumonia Caused by Various Bacteria, including Acinetobacter baumannii by Onita, Tetsushu, Ikawa, Kazuro, Ishihara, Noriyuki, Tamaki, Hiroki, Yano, Takahisa, Naora, Kohji, Morikawa, Norifumi

“…This study aimed to assess the dosing regimens of ampicillin/sulbactam for pneumonia based on pulmonary pharmacokinetic (PK)/pharmacodynamic (PD) target…”
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Dietary Fiber Deficiency Accelerates Colitis in Mice in the Short Term Independent of Short-Chain Fatty Acids by Kanda, Shoma, Usuda, Haruki, Karino, Sonoko, Okamoto, Takayuki, Niibayashi, Tomomi, Yano, Takahisa, Naora, Kohji, Wada, Koichiro

“…It is believed that short-chain fatty acids (SCFAs)—the bacterial metabolites produced by the digestion of dietary fiber—potentially contribute to the…”
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Involvement of Spinal NR2B-Containing NMDA Receptors in Oxaliplatin-Induced Mechanical Allodynia in Rats by Mihara, Yuki, Egashira, Nobuaki, Sada, Hikaru, Kawashiri, Takehiro, Ushio, Soichiro, Yano, Takahisa, Ikesue, Hiroaki, Oishi, Ryozo

“…Background: Oxaliplatin is a platinum-based chemotherapy drug characterized by the development of acute and chronic peripheral neuropathies. The chronic…”
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Identification of candidate pathogens of papillomatous digital dermatitis in dairy cattle from quantitative 16S rRNA clonal analysis by Yano, Takahisa, Moe, Kyaw Kyaw, Yamazaki, Kazuko, Ooka, Tadasuke, Hayashi, Tetsuya, Misawa, Naoaki

“…Although it is suspected that papillomatous digital dermatitis (PDD), an infectious foot disease of cattle, is caused by multiple bacteria, it remains unclear…”
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Integrated Synthetic Strategy for Higher Catechin Oligomers by Ohmori, Ken, Shono, Tomohiro, Hatakoshi, Yuki, Yano, Takahisa, Suzuki, Keisuke

“…Chain linked: An integrated strategy for the rapid assembly of catechin oligomers has been developed, thus enabling access to higher oligomers ranging from 6‐…”
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Activation of p38 MAPK by oxidative stress underlying epirubicin-induced vascular endothelial cell injury by Yamada, Takaaki, Egashira, Nobuaki, Bando, Ayami, Nishime, Yui, Tonogai, Yuki, Imuta, Maiko, Yano, Takahisa, Oishi, Ryozo

“…Epirubicin, an anthracycline antitumor drug, often causes vascular injury such as vascular pain, phlebitis, and necrotizing vasculitis. However, an effective…”
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Development of molecular diagnostic protocols for detecting three types of Entamoeba from diarrheal and asymptomatic pigs and environmental moist soils by Hirashima, Yoshimasa, Manchanayake, Tilusha, Yano, Takahisa, Kitahara, Syoei, Koreeda, Terunori, Kamimura, Syunsuke, Sasai, Kazumi, Matsubayashi, Makoto, Shibahara, Tomoyuki

“…Entamoeba suis and Entamoeba polecki subtypes (ST) 1 and 3 have recently been implicated in disease outbreaks in pigs. However, the distributions of these…”
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Prevention of oxaliplatin-induced mechanical allodynia and neurodegeneration by neurotropin in the rat model by Kawashiri, Takehiro, Egashira, Nobuaki, Watanabe, Hitomi, Ikegami, Yoko, Hirakawa, Shingo, Mihara, Yuki, Yano, Takahisa, Ikesue, Hiroaki, Oishi, Ryozo

“…Abstract Oxaliplatin is a key drug for colorectal cancer, but it causes acute peripheral neuropathy (triggered by cold) and chronic neuropathy (sensory and…”
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Assessment of Renal Function and Simulation Using Serum Cystatin-C in an Elderly Patient with Uncontrollable Plasma Vancomycin Levels Due to Muscular Dystrophy: A Case Report by Onita, Tetsushu, Ishihara, Noriyuki, Yano, Takahisa, Nishimura, Nobuhiro, Tamaki, Hiroki, Ikawa, Kazuro, Morikawa, Norifumi, Naora, Kohji

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Mexiletine Reverses Oxaliplatin-Induced Neuropathic Pain in Rats by Egashira, Nobuaki, Hirakawa, Shingo, Kawashiri, Takehiro, Yano, Takahisa, Ikesue, Hiroaki, Oishi, Ryozo

“…Oxaliplatin is a platinum-based chemotherapy drug characterized by the development of acute and chronic peripheral neuropathies. Mexiletine, an orally…”
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Evaluation of teicoplanin concentrations and safety analysis in neonates by Yamada, Takaaki, Kubota, Toshio, Nakamura, Masako, Ochiai, Masayuki, Yonezawa, Mahoro, Yano, Takahisa, Kawashiri, Takehiro, Egashira, Nobuaki, Hara, Toshiro, Masuda, Satohiro

“…Highlights • Recommended teicoplanin dosage for neonates is appropriate to achieve ≥15 μg/mL. • Teicoplanin trough concentration depends on both body weight…”
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Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Simulation of Piperacillin/Tazobactam for Dosing Optimization in Late Elderly Patients with Pneumonia by Ishihara, Noriyuki, Nishimura, Nobuhiro, Ikawa, Kazuro, Karino, Fumi, Miura, Kiyotaka, Tamaki, Hiroki, Yano, Takahisa, Isobe, Takeshi, Morikawa, Norifumi, Naora, Kohji

“…The aim of this study was to develop a population pharmacokinetic model for piperacillin (PIPC)/tazobactam (TAZ) in late elderly patients with pneumonia and to…”
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