Search Results - "Yang, Zhonghan"

Metformin selectively inhibits metastatic colorectal cancer with the KRAS mutation by intracellular accumulation through silencing MATE1 by Xie, Jinye, Xia, Liangping, Xiang, Wei, He, Wenzhuo, Yin, Haofan, Wang, Fang, Gao, Tianxiao, Qi, Weiwei, Yang, Zhonghan, Yang, Xia, Zhou, Ti, Gao, Guoquan

“…Metastatic colorectal cancer (mCRC) patients have poor overall survival despite using irinotecan- or oxaliplatin-based chemotherapy combined with anti-EGFR…”
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IL-25-induced shifts in macrophage polarization promote development of beige fat and improve metabolic homeostasis in mice by Li, Lingyi, Ma, Lei, Zhao, Zewei, Luo, Shiya, Gong, Baoyong, Li, Jin, Feng, Juan, Zhang, Hui, Qi, Weiwei, Zhou, Ti, Yang, Xia, Gao, Guoquan, Yang, Zhonghan

“…Beige fat dissipates energy and functions as a defense against cold and obesity, but the mechanism for its development is unclear. We found that interleukin…”
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Intestinal dysbacteriosis-induced IL-25 promotes development of HCC via alternative activation of macrophages in tumor microenvironment by Li, Qiao, Ma, Lei, Shen, Shunli, Guo, Yu, Cao, Qinghua, Cai, Xiuqin, Feng, Juan, Yan, Yuan, Hu, Tianyu, Luo, Shiya, Zhou, Lin, Peng, Baogang, Yang, Zhonghan, Hua, Yunpeng

“…Gut microbiota and the tumor microenvironment are thought to be critical factors that modulate the processes of liver diseases, including hepatocellular…”
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IL-25 stimulates M2 macrophage polarization and thereby promotes mitochondrial respiratory capacity and lipolysis in adipose tissues against obesity by Feng, Juan, Li, Lingyi, Ou, Zhiying, Li, Qiao, Gong, Baoyong, Zhao, Zhenxian, Qi, Weiwei, Zhou, Ti, Zhong, Jun, Cai, Weibin, Yang, Xia, Zhao, Aiping, Gao, Guoquan, Yang, Zhonghan

“…Obesity and associated metabolic diseases are characterized by a chronic low-grade inflammatory state with the infiltration of many inflammatory cells,…”
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FUBP1 promotes colorectal cancer stemness and metastasis via DVL1‐mediated activation of Wnt/β‐catenin signaling by Yin, Haofan, Gao, Tianxiao, Xie, Jinye, Huang, Zhijian, Zhang, Xiaoyan, Yang, Fengyu, Qi, Weiwei, Yang, Zhonghan, Zhou, Ti, Gao, Guoquan, Yang, Xia

“…Distant metastasis is, unfortunately, the leading cause of death in colorectal cancer (CRC). Approximately 50% of CRC patients develop liver metastases, while…”
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Nanoparticle (NP)-mediated APOC1 silencing to inhibit MAPK/ERK and NF-κB pathway and suppress breast cancer growth and metastasis by Liu, Shaomin, Zhang, Fengqian, Liang, Yixia, Wu, Guo, Liu, Rong, Li, Xiuling, Saw, Phei Er, Yang, Zhonghan

“…Breast cancer is one of the most common malignant tumors with high mortality and poor prognosis in women. There is an urgent need to discover new therapeutic…”
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PEDF inhibits lymphatic metastasis of nasopharyngeal carcinoma as a new lymphangiogenesis inhibitor by Luo, Chuanghua, Yin, Haofan, Gao, Tianxiao, Ma, Caiqi, Liu, Junxi, Zhang, Ting, Xu, Zumin, Wang, Xi, Zhang, Danrui, Qi, Weiwei, Yang, Zhonghan, Gao, Guoquan, Yang, Xia, Zhou, Ti

“…Nasopharyngeal carcinoma (NPC) is one of the most malignant tumors in southern China and Asia, and lymph node metastasis is an important cause for treatment…”
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Elevated pigment epithelium-derived factor induces diabetic erectile dysfunction via interruption of the Akt/Hsp90β/eNOS complex by Che, Di, Fang, Zhenzhen, Yan, Li, Du, Jieping, Li, Fangping, Xie, Jinye, Feng, Juan, Yin, Ping, Qi, Weiwei, Yang, Zhonghan, Ma, Jianxing, Yang, Xia, Gao, Guoquan, Zhou, Ti

“…Aims/hypothesis Diabetes mellitus erectile dysfunction (DMED) is a common complication of diabetes. The level of pigment epithelium-derived factor (PEDF) is…”
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Parasitic Nematode-Induced Modulation of Body Weight and Associated Metabolic Dysfunction in Mouse Models of Obesity by Yang, Zhonghan, Grinchuk, Viktoriya, Smith, Allen, Qin, Bolin, Bohl, Jennifer A, Sun, Rex, Notari, Luigi, Zhang, Zhongyan, Sesaki, Hiromi, Urban, Jr, Joseph F, Shea-Donohue, Terez, Zhao, Aiping

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Macrophages as IL-25/IL-33-responsive cells play an important role in the induction of type 2 immunity by Yang, Zhonghan, Grinchuk, Viktoriya, Urban, Jr, Joseph F, Bohl, Jennifer, Sun, Rex, Notari, Luigi, Yan, Shu, Ramalingam, Thirumalai, Keegan, Achsah D, Wynn, Thomas A, Shea-Donohue, Terez, Zhao, Aiping

“…Type 2 immunity is essential for host protection against nematode infection but is detrimental in allergic inflammation or asthma. There is a major research…”
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Abnormal bile acid-microbiota crosstalk promotes the development of hepatocellular carcinoma by Shen, Rui, Ke, Lixin, Li, Qiao, Dang, Xi, Shen, Shunli, Shen, Jianming, Li, Shaoqiang, Liang, Lijian, Peng, Baogang, Kuang, Ming, Ma, Yi, Yang, Zhonghan, Hua, Yunpeng

“…Background Gut microbiota and microbe-derived metabolites are involved in the development of HCC. Bile acids (BAs) are the most important gut…”
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Kallistatin inhibits lymphangiogenesis and lymphatic metastasis of gastric cancer by downregulating VEGF-C expression and secretion by Ma, Caiqi, Luo, Chuanghua, Yin, Haofan, Zhang, Yang, Xiong, Wenjun, Zhang, Ting, Gao, Tianxiao, Wang, Xi, Che, Di, Fang, Zhenzhen, Li, Lei, Xie, Jinye, Huang, Mao, Zhu, Liuqing, Jiang, Ping, Qi, Weiwei, Zhou, Ti, Yang, Zhonghan, Wang, Wei, Ma, Jianxing, Gao, Guoquan, Yang, Xia

“…Background Tumor-induced lymphangiogenesis and lymphatic metastasis are predominant during the metastasis of many types of cancers. However, the endogenous…”
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Protective effect and mechanism of action of mulberry marc anthocyanins on carbon tetrachloride-induced liver fibrosis in rats by Li, Yuxian, Yang, Zhonghan, Jia, Shanshan, Yuan, Ke

“…•The content of anthocyanins in mulberry marc was higher than in mulberry juices.•Mulberry marc anthocyanins can be obtained widely and cheaply from raw…”
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IL25 Enhanced Colitis-Associated Tumorigenesis in Mice by Upregulating Transcription Factor GLI1 by Liu, Junxi, Qian, Bingxiu, Zhou, Lin, Shen, Gang, Tan, Yandan, Liu, Siqi, Zhao, Zewei, Shi, Jianglin, Qi, Weiwei, Zhou, Ti, Yang, Xia, Gao, Guoquan, Yang, Zhonghan

“…Interleukin-25 (IL17E/IL25) plays a critical role in colitis and intestinal homeostasis. However, the expression and biological role of IL25 in colorectal…”
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Combination of pigment epithelium‐derived factor with radiotherapy enhances the antitumor effects on nasopharyngeal carcinoma by downregulating vascular endothelial growth factor expression and angiogenesis by Xu, Zumin, Fang, Shuhuan, Zuo, Yufang, Zhang, Yang, Cheng, Rui, Wang, Qingsong, Yang, Zhonghan, Cai, Weibin, Ma, Jianxing, Yang, Xia, Gao, Guoquan

“…Nasopharyngeal carcinoma (NPC), which has the highest incidence in South China, is mainly treated by radiotherapy. However, the survival rate remains low…”
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FUBP1 promotes neuroblastoma proliferation via enhancing glycolysis-a new possible marker of malignancy for neuroblastoma by Jiang, Ping, Huang, Mao, Qi, Weiwei, Wang, Fenghua, Yang, Tianyou, Gao, Tianxiao, Luo, Chuanghua, Deng, Jing, Yang, Zhonghan, Zhou, Ti, Zou, Yan, Gao, Guoquan, Yang, Xia

“…Neuroblastoma (NB) is one of the deadliest paediatric solid tumours due to its rapid proliferative characteristics. Amplified copies of MYCN are considered the…”
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Critical role of IL-25 in nematode infection-induced alterations in intestinal function by Zhao, Aiping, Urban, Jr, Joseph F, Sun, Rex, Stiltz, Jennifer, Morimoto, Motoko, Notari, Luigi, Madden, Kathleen B, Yang, Zhonghan, Grinchuk, Viktoriya, Ramalingam, Thirumalai R, Wynn, Thomas A, Shea-Donohue, Terez

“…IL-25 (IL-17E) is a member of the IL-17 cytokine family. IL-25-deficient mice exhibit impaired Th2 immunity against nematode infection, implicating IL-25 as a…”
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CMKLR1 senses chemerin/resolvin E1 to control adipose thermogenesis and modulate metabolic homeostasis by Zhao, Zewei, Liu, Siqi, Qian, Bingxiu, Zhou, Lin, Shi, Jianglin, Liu, Junxi, Xu, Lin, Yang, Zhonghan

“…Induction of beige fat for thermogenesis is a potential therapy to improve homeostasis against obesity. β3-adrenoceptor (β3-AR), a type of G protein-coupled…”
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Pigment epithelium‐derived factor/vascular endothelial growth factor ratio plays a crucial role in the spontaneous regression of infant hemangioma and in the therapeutic effect of propranolol by Zhu, Liuqing, Xie, Jinye, Liu, Zhenyin, Huang, Zhijian, Huang, Mao, Yin, Haofan, Qi, Weiwei, Yang, Zhonghan, Zhou, Ti, Gao, Guoquan, Zhang, Jing, Yang, Xia

“…Infantile hemangioma (IH) is a benign tumor that is formed by aberrant angiogenesis and that undergoes spontaneous regression over time. Propranolol, the…”
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IL-25 or IL-17E Protects against High-Fat Diet-Induced Hepatic Steatosis in Mice Dependent upon IL-13 Activation of STAT6 by Wang, An-Jiang, Yang, Zhonghan, Grinchuk, Viktoriya, Smith, Allen, Qin, Bolin, Lu, Nonghua, Wang, Duan, Wang, Hongbing, Ramalingam, Thirumalai R, Wynn, Thomas A, Urban, Jr, Joseph F, Shea-Donohue, Terez, Zhao, Aiping

“…IL-25 or IL-17E is a member of IL-17 cytokine family and has immune-modulating activities. The role of IL-25 in maintaining lipid metabolic homeostasis remains…”
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