Search Results - "Yang, Zhilai"

Long-lasting postoperative analgesia with local anesthetic-loaded hydrogels prevent tumor recurrence via enhancing CD8 + T cell infiltration by Zhao, Mingxu, Zhu, Shasha, Zhang, Ding, Zhou, Chang, Yang, Zhilai, Wang, Chunhui, Liu, Xuesheng, Zhang, Jiqian

“…Postoperative pain (POP) can promote tumor recurrence and reduce the cancer patient's quality of life. However, POP management has always been separated from…”
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Ropivacaine-loaded hydrogels for prolonged relief of chemotherapy-induced peripheral neuropathic pain and potentiated chemotherapy by Qing, Xin, Dou, Renbin, Wang, Peng, Zhou, Mengni, Cao, Chenchen, Zhang, Huiwen, Qiu, Gaolin, Yang, Zhilai, Zhang, Jiqian, Liu, Hu, Zhu, Shasha, Liu, Xuesheng

“…Abstract Chemotherapy can cause severe pain for patients, but there are currently no satisfactory methods of pain relief. Enhancing the efficacy of…”
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Mannose-coated superparamagnetic iron oxide nanozyme for preventing postoperative cognitive dysfunction by Zhu, Qianyun, Huang, Yuting, Zhu, Xiaoling, Peng, Lijun, Wang, Huan, Gao, Shan, Yang, Zhilai, Zhang, Jiqian, Liu, Xuesheng

“…Postoperative cognitive dysfunction (POCD) is associated with increased postoperative morbidity and mortality in patients. Excessive production of reactive…”
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Caloric Restriction Alleviates CFA-Induced Inflammatory Pain via Elevating β-Hydroxybutyric Acid Expression and Restoring Autophagic Flux in the Spinal Cord by Liu, Chang, Zheng, Xiaoting, Liu, Lifang, Hu, Yun, Zhu, Qianyun, Zhang, Jiawei, Wang, Huan, Gu, Er-Wei, Yang, Zhilai, Xu, Guanghong

“…Inflammatory pain is the most common type of pain encountered in clinical practice; however, the currently available treatments are limited by insufficient…”
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The characteristic of the complete chloroplast genome of Lithocarpus konishii (Fagaceae), a rare and endemic species in South China by Fu, Keyi, Lu, Linjing, Ding, Mingyan, Yang, Zhilai, Shen, Hongkang, Shi, Shi

“…Lithocarpus konishii, a rare species endemic to islands in South China, was evaluated as a vulnerable species (VU) by the 'China Species Red List.' Here, we…”
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Mannose-coated nanozyme for relief from chemotherapy-induced peripheral neuropathic pain by Liu, Hu, Qing, Xin, Peng, Lijun, Zhang, Ding, Dai, Wei, Yang, Zhilai, Zhang, Jiqian, Liu, Xuesheng

“…Chemotherapy-induced peripheral neuropathic pain (CIPNP) is a progressive and disturbing peripheral neuropathy with currently no effective treatment. Aberrant…”
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The Changes of Intrinsic Excitability of Pyramidal Neurons in Anterior Cingulate Cortex in Neuropathic Pain by Yang, Zhilai, Tan, Qilian, Cheng, Dan, Zhang, Lei, Zhang, Jiqian, Gu, Er-Wei, Fang, Weiping, Lu, Xianfu, Liu, Xuesheng

“…To find satisfactory treatment strategies for neuropathic pain syndromes, the cellular mechanisms should be illuminated. Central sensitization is a generator…”
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Midazolam Enhances Mutant Huntingtin Protein Accumulation via Impairment of Autophagic Degradation In Vitro by Zhang, Jiqian, Dai, Wei, Geng, Pengcheng, Zhang, Li, Tan, Qilian, Cheng, Dan, Wei, Pengfei, Yang, Zhilai, Zhang, Lei, Gu, Erwei, Xu, Guanghong, Liang, Chaozhao, Liu, Xuesheng

“…Background/Aims: Autophagy is a well-known pathway to “clean” the misfolded mutant huntingtin protein (mHtt), which plays a considerable role in polyglutamine…”
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Frequency-Dependent Reliability of Spike Propagation Is Function of Axonal Voltage-Gated Sodium Channels in Cerebellar Purkinje Cells by Yang, Zhilai, Wang, Jin-Hui

“…The spike propagation on nerve axons, like synaptic transmission, is essential to ensure neuronal communication. The secure propagation of sequential spikes…”
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Essential role of axonal VGSC inactivation in time-dependent deceleration and unreliability of spike propagation at cerebellar Purkinje cells by Yang, Zhilai, Gu, Erwei, Lu, Xianfu, Wang, Jin-Hui

“…The output of the neuronal digital spikes is fulfilled by axonal propagation and synaptic transmission to influence postsynaptic cells. Similar to synaptic…”
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Malondialdehyde suppresses cerebral function by breaking homeostasis between excitation and inhibition in turtle Trachemys scripta by Li, Fangxu, Yang, Zhilai, Lu, Yang, Wei, Yan, Wang, Jinhui, Yin, Dazhong, He, Rongqiao

“…The levels of malondialdehyde (MDA) are high in the brain during carbonyl stress, such as following daily activities and sleep deprivation. To examine our…”
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Ischemia deteriorates the spike encoding of rat cerebellar Purkinje cells by raising intracellular Ca{sup 2+} by Zhao Shidi, Chen Na, Yang Zhilai, Huang Li, Zhu Yan, Guan Sudong, Chen Qianfen, Wang Jinhui

“…Ischemia-induced excitotoxicity at cerebellar Purkinje cells is presumably due to a persistent glutamate action. To the fact that they are more vulnerable to…”
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Rosavin protects the blood–brain barrier against ischemia/reperfusion‐induced cerebral injury by regulating MAPK‐mediated MMPs pathway by Zou, Hongyun, Li, Lei, Yang, Zhilai, Tang, Lili, Wang, Chunhui

“…Ischemia–reperfusion (I/R) injury is a common pathophysiological condition in ischemic stroke, involving various pathophysiological events, such as…”
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Enhanced autophagic flux contributes to cardioprotection of remifentanil postconditioning after hypoxia/reoxygenation injury in H9c2 cardiomyocytes by Zuo, Youmei, Zhang, Jiqian, Cheng, Xinqi, Li, Jun, Yang, Zhilai, Liu, Xuesheng, Gu, Erwei, Zhang, Ye

“…Remifentanil postconditioning (RPC) has been shown to provide potent cardioprotection against ischemia/reperfusion (I/R) injury, but the underlying mechanism…”
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Dexmedetomidine Inhibits Paraventricular Corticotropin-releasing Hormone Neurons that Attenuate Acute Stress-induced Anxiety-like Behavior in Mice by Qiu, Gaolin, Wang, Peng, Rao, Jin, Qing, Xin, Cao, Chenchen, Wang, Dijia, Mei, Bin, Zhang, Jiqian, Liu, Hu, Yang, Zhilai, Liu, Xuesheng

“…Dexmedetomidine has repeatedly shown to improve anxiety, but the precise neural mechanisms underlying this effect remain incompletely understood. This study…”
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Kupffer cell-targeting strategy for the protection of hepatic ischemia/reperfusion injury by Dai, Qingqing, Jiang, Wei, Liu, Hu, Qing, Xin, Wang, Guobin, Huang, Fan, Yang, Zhilai, Wang, Chunhui, Gu, Erwei, Zhao, Hongchuan, Zhang, Jiqian, Liu, Xuesheng

“…The aim of this study is to evaluate the effect of rare earth upconversion nanoparticles (UCNs) on hepatic ischemia reperfusion injury (IRI) and explore its…”
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Analgesic and potentiated photothermal therapy with ropivacaine-loaded hydrogels by Zhang, Jiqian, Zhu, Shasha, Zhao, Mingxu, Zhou, Mengni, Zhu, Xiaoling, Qing, Xin, Yang, Zhilai, Wei, Pengfei, Zhang, Guoying, He, Weiling, Yu, Yongqiang, Liu, Xuesheng

“…Tumor ablation can cause severe pain to patients, but there is no satisfactory means of analgesia available. In addition, recurrence of residual tumors due to…”
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Nano C60 Promotes Synaptic Distribution of Phosphorylated CaMKIIα and Improves Cognitive Function in APP/PS1 Transgenic Mice by Dai, Wei, Zhao, Mingxu, Chen, Caiyun, Zhou, Chang, Wang, Peng, Yang, Zhilai, Gao, Shan, Lu, Yao, Zhang, Jiqian, Liu, Xuesheng

“…The wide disparity in outcomes of Alzheimer’s disease (AD) treatment from preclinical to clinical studies suggests an urgent need for more effective…”
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Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice by Zhang, Jiqian, Zhu, Shasha, Jin, Peipei, Huang, Yuting, Dai, Qingqing, Zhu, Qianyun, Wei, Pengfei, Yang, Zhilai, Zhang, Lei, Liu, Hu, Xu, Guanghong, Chen, Lijian, Gu, Erwei, Zhang, Yunjiao, Wen, Longping, Liu, Xuesheng

“…Rationale: Graphene oxide (GO) based nanomaterials have shown potential for the diagnosis and treatment of amyloid-β (Aβ)-related diseases, mainly on…”
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Combination therapy with ropivacaine-loaded liposomes and nutrient deprivation for simultaneous cancer therapy and cancer pain relief by Zhang, Jiqian, Zhu, Shasha, Tan, Qilian, Cheng, Dan, Dai, Qingqing, Yang, Zhilai, Zhang, Lei, Li, Fenfen, Zuo, Youmei, Dai, Wei, Chen, Lihai, Gu, Erwei, Xu, Guanghong, Wei, Zhaolian, Cao, Yunxia, Liu, Xuesheng

“…Autophagy allows cancer cells to respond changes in nutrient status by degrading and recycling non-essential intracellular contents. Inhibition of autophagy…”
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