Search Results - "Yang, YouFeng"

Reductive carboxylation supports growth in tumour cells with defective mitochondria by Mullen, Andrew R., Wheaton, William W., Jin, Eunsook S., Chen, Pei-Hsuan, Sullivan, Lucas B., Cheng, Tzuling, Yang, Youfeng, Linehan, W. Marston, Chandel, Navdeep S., DeBerardinis, Ralph J.

“…Tumour cells with defective mitochondria are found to use glutamine-dependent reductive carboxylation, rather than oxidative metabolism, as the major pathway…”
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Impaired intracellular calcium homeostasis enhances protein O-GlcNAcylation and promotes vascular calcification and stiffness in diabetes by Zhang, Weiping, Sun, Yong, Yang, Youfeng, Chen, Yabing

“…Vascular calcification is accelerated in patients with diabetes mellitus and increases risk of cardiovascular events and mortality. Vascular smooth muscle…”
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Negative effects of lifespan extending intervention on resilience in mice by Corder, Katelynn M, Hoffman, Jessica M, Sogorovic, Anamarija, Yang, Youfeng, Banerjee, Anisha, Sun, Yi, Stout, Michael B, Austad, Steven N

“…One key goal of basic aging research is the development of reliable assays of both current and future health. These assays could dramatically accelerate…”
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A lactobacilli-based inhaled live biotherapeutic product attenuates pulmonary neutrophilic inflammation by Nicola, Teodora, Wenger, Nancy, Xu, Xin, Evans, Michael, Qiao, Luhua, Rezonzew, Gabriel, Yang, Youfeng, Jilling, Tamas, Margaroli, Camilla, Genschmer, Kristopher, Willis, Kent, Ambalavanan, Namasivayam, Blalock, J. Edwin, Gaggar, Amit, Lal, Charitharth Vivek

“…Bronchopulmonary dysplasia (BPD) is a chronic lung disease of prematurity. Exposure to noxious stimuli such as hyperoxia, volutrauma, and infection in infancy…”
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Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer by Ricketts, Christopher J, Shuch, Brian, Vocke, Cathy D, Metwalli, Adam R, Bratslavsky, Gennady, Middelton, Lindsay, Yang, Youfeng, Wei, Ming-Hui, Pautler, Stephen E, Peterson, James, Stolle, Catherine A, Zbar, Berton, Merino, Maria J, Schmidt, Laura S, Pinto, Peter A, Srinivasan, Ramaprasad, Pacak, Karel, Linehan, W Marston

“…Recently, a new renal cell cancer syndrome has been linked to germline mutation of multiple subunits (SDHB/C/D) of the Krebs cycle enzyme, succinate…”
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The Glycolytic Shift in Fumarate-Hydratase-Deficient Kidney Cancer Lowers AMPK Levels, Increases Anabolic Propensities and Lowers Cellular Iron Levels by Tong, Wing-Hang, Sourbier, Carole, Kovtunovych, Gennady, Jeong, Suh Young, Vira, Manish, Ghosh, Manik, Romero, Vladimir Valera, Sougrat, Rachid, Vaulont, Sophie, Viollet, Benoit, Kim, Yeong-Sang, Lee, Sunmin, Trepel, Jane, Srinivasan, Ramaprasad, Bratslavsky, Gennady, Yang, Youfeng, Linehan, W. Marston, Rouault, Tracey A.

“…Inactivation of the TCA cycle enzyme, fumarate hydratase ( FH), drives a metabolic shift to aerobic glycolysis in FH-deficient kidney tumors and cell lines…”
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Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1α Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species by Sudarshan, Sunil, Sourbier, Carole, Kong, Hye-Sik, Block, Karen, Romero, Vladimir A. Valera, Yang, Youfeng, Galindo, Cynthia, Mollapour, Mehdi, Scroggins, Bradley, Goode, Norman, Lee, Min-Jung, Gourlay, Campbell W., Trepel, Jane, Linehan, W. Marston, Neckers, Len

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Targeting ABL1-Mediated Oxidative Stress Adaptation in Fumarate Hydratase-Deficient Cancer by Sourbier, Carole, Ricketts, Christopher J., Matsumoto, Shingo, Crooks, Daniel R., Liao, Pei-Jyun, Mannes, Philip Z., Yang, Youfeng, Wei, Ming-Hui, Srivastava, Gaurav, Ghosh, Sanchari, Chen, Viola, Vocke, Cathy D., Merino, Maria, Srinivasan, Ramaprasad, Krishna, Murali C., Mitchell, James B., Pendergast, Ann Marie, Rouault, Tracey A., Neckers, Len, Linehan, W. Marston

“…Patients with germline fumarate hydratase (FH) mutation are predisposed to develop aggressive kidney cancer with few treatment options and poor therapeutic…”
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AKT-independent activation of p38 MAP kinase promotes vascular calcification by Yang, Youfeng, Sun, Yong, Chen, Jianye, Bradley, Wayne E., Dell’Italia, Louis J., Wu, Hui, Chen, Yabing

“…Vascular calcification is prevalent in patients with atherosclerosis, and oxidative stress promotes pathogenesis of atherosclerosis. We have previously…”
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Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma by Yang, Youfeng, Lane, Andrew N, Ricketts, Christopher J, Sourbier, Carole, Wei, Ming-Hui, Shuch, Brian, Pike, Lisa, Wu, Min, Rouault, Tracey A, Boros, Laszlo G, Fan, Teresa W-M, Linehan, W Marston

“…Fumarate hydratase (FH)-deficient kidney cancer undergoes metabolic remodeling, with changes in mitochondrial respiration, glucose, and glutamine metabolism…”
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In-Plane Radiation of Surface Plasmon Polaritons Excited by Free Electrons by Zhang, Ping, Dong, Yin, Li, Xubo, Cao, Xinxin, Yang, Youfeng, Yu, Guohao, Yang, Shengpeng, Wang, Shaomeng, Gong, Yubin

“…Surface plasmon polaritons (SPPs) have become a research hotspot due to their high intensity and subwavelength localization. Through free-electron excitation,…”
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Preclinical efficacy of dual mTORC1/2 inhibitor AZD8055 in renal cell carcinoma harboring a TFE3 gene fusion by Kauffman, Eric C, Lang, Martin, Rais-Bahrami, Soroush, Gupta, Gopal N, Wei, Darmood, Yang, Youfeng, Sourbier, Carole, Srinivasan, Ramaprasad

“…Renal cell carcinomas (RCC) harboring a TFE3 gene fusion (TfRCC) represent an aggressive subset of kidney tumors. Key signaling pathways of TfRCC are unknown…”
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Dual-color, Break-apart FISH Assay on Paraffin-embedded Tissues as an Adjunct to Diagnosis of Xp11 Translocation Renal Cell Carcinoma and Alveolar Soft Part Sarcoma by MINGHAO ZHONG, DE ANGELO, Patricia, HAMEED, Meera, OSBORNE, Lisa, KEANE-TARCHICHI, Megan, GOLDFISCHER, Michael, EDELMANN, Elisa, YOUFENG YANG, LINEHAN, W. Marston, MERINO, Maria J, AISNER, Seena

“…Both Xp11.2 translocation renal cell carcinoma (RCC) and alveolar soft part sarcoma (ASPS) are characterized by various translocations disrupting chromosome…”
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The Amyotrophic Lateral Sclerosis 8 Protein VAPB Is Cleaved, Secreted, and Acts as a Ligand for Eph Receptors by Tsuda, Hiroshi, Han, Sung Min, Yang, Youfeng, Tong, Chao, Lin, Yong Qi, Mohan, Kriti, Haueter, Claire, Zoghbi, Anthony, Harati, Yadollah, Kwan, Justin, Miller, Michael A., Bellen, Hugo J.

“…VAP proteins (human VAPB/ALS8, Drosophila VAP33, and C. elegans VPR-1) are homologous proteins with an amino-terminal major sperm protein (MSP) domain and a…”
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Insulin/FOXO Signaling Regulates Ovarian Prostaglandins Critical for Reproduction by Edmonds, Johnathan W., Prasain, Jeevan K., Dorand, Dixon, Yang, Youfeng, Hoang, Hieu D., Vibbert, Jack, Kubagawa, Homare M., Miller, Michael A.

“…Abnormalities in insulin/IGF-1 signaling are associated with infertility, but the molecular mechanisms are not well understood. Here we use liquid…”
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Tumor-Infiltrating Myeloid Cells Co-Express TREM1 and TREM2 and Elevated TREM-1 Associates With Disease Progression in Renal Cell Carcinoma by Ford, Jill W, Gonzalez-Cotto, Marieli, MacFarlane, 4th, Alexander W, Peri, Suraj, Howard, O M Zack, Subleski, Jeffrey J, Ruth, Karen J, Haseebuddin, Mohammed, Al-Saleem, Tahseen, Yang, Youfeng, Rayman, Pat, Rini, Brian, Linehan, W Marston, Finke, James, Weiss, Jonathan M, Campbell, Kerry S, McVicar, Daniel W

“…Myeloid-derived suppressor cells (MDSC) and tumor-associated macrophages (TAM) contribute to cancer-related inflammation and tumor progression. While several…”
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High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma by Lang, Martin, Schmidt, Laura S, Wilson, Kelli M, Ricketts, Christopher J, Sourbier, Carole, Vocke, Cathy D, Wei, Darmood, Crooks, Daniel R, Yang, Youfeng, Gibbs, Benjamin K, Zhang, Xiaohu, Klumpp-Thomas, Carleen, Chen, Lu, Guha, Rajarshi, Ferrer, Marc, McKnight, Crystal, Itkin, Zina, Wangsa, Darawalee, Wangsa, Danny, James, Amy, Difilippantonio, Simone, Karim, Baktir, Morís, Francisco, Ried, Thomas, Merino, Maria J, Srinivasan, Ramaprasad, Thomas, Craig J, Linehan, W Marston

“…MiT-Renal Cell Carcinoma (RCC) is characterized by genomic translocations involving microphthalmia-associated transcription factor (MiT) family members TFE3,…”
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VPO1 mediates ApoE oxidation and impairs the clearance of plasma lipids by Yang, Youfeng, Cao, Zehong, Tian, Ling, Garvey, W Timothy, Cheng, Guangjie

“…ApoE is an abundant component of chylomicron, VLDL, IDL, and HDL. It binds to multiple types of lipids and is implicated in cholesterol and triglyceride…”
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Secreted VAPB/ALS8 Major Sperm Protein Domains Modulate Mitochondrial Localization and Morphology via Growth Cone Guidance Receptors by Han, Sung Min, Tsuda, Hiroshi, Yang, Youfeng, Vibbert, Jack, Cottee, Pauline, Lee, Se-Jin, Winek, Jessica, Haueter, Claire, Bellen, Hugo J., Miller, Michael A.

“…The VAPB/ALS8 major sperm protein domain (vMSP) is implicated in amyotrophic lateral sclerosis and spinal muscular atrophy, yet its function in the nervous…”
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Comprehensive genomic and phenotypic characterization of germline FH deletion in hereditary leiomyomatosis and renal cell carcinoma by Vocke, Cathy D., Ricketts, Christopher J., Merino, Maria J., Srinivasan, Ramaprasad, Metwalli, Adam R., Middelton, Lindsay A., Peterson, James, Yang, Youfeng, Linehan, W. Marston

“…Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is a familial cancer syndrome associated with the development of cutaneous and uterine leiomyomas,…”
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