Search Results - "Yang, Yeming"

Tmem30a deficiency leads to retinal rod bipolar cell degeneration by Yang, Yeming, Liu, Wenjing, Sun, Kuanxiang, Jiang, Li, Zhu, Xianjun

“…Phospholipids are asymmetrically distributed across the mammalian plasma membrane, with phosphatidylserine (PS) and phosphatidylethanolamine concentrated in…”
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Loss of the ER membrane protein complex subunit Emc3 leads to retinal bipolar cell degeneration in aged mice by Zhu, Xiong, Qi, Xin, Yang, Yeming, Tian, Wanli, Liu, Wenjing, Jiang, Zhilin, Li, Shuzhen, Zhu, Xianjun

“…The endoplasmic reticulum (ER) membrane protein complex (EMC) is a conserved protein complex involved in inserting the transmembrane domain of membrane…”
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TMEM30A deficiency in endothelial cells impairs cell proliferation and angiogenesis by Zhang, Shanshan, Liu, Wenjing, Yang, Yeming, Sun, Kuanxiang, Li, Shujin, Xu, Huijuan, Yang, Mu, Zhang, Lin, Zhu, Xianjun

“…Phosphatidylserine (PS) asymmetry in the eukaryotic cell membrane is maintained by a group of proteins belonging to the P4-ATPase family, namely, PS flippases…”
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Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice by Xu, Huijuan, Qu, Chao, Gan, Li, Sun, Kuanxiang, Tan, Junkai, Liu, Xuyang, Jiang, Zhilin, Tian, Wanli, Liu, Wenjing, Zhang, Shanshan, Yang, Yeming, Jiang, Li, Zhu, Xianjun, Zhang, Lin

“…Abstract Variants in interphotoreceptor matrix proteoglycans (IMPG2) have been reported in retinitis pigmentosa (RP) and vitelliform macular dystrophy (VMD)…”
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Three-Party Password Authentication and Key Exchange Protocol Based on MLWE by Guo, Songhui, Song, Yunfan, Guo, Song, Yang, Yeming, Song, Shuaichao

“…With the rapid development of quantum theory, the discrete logarithm problem and significant integer factorization problem have polynomial solution algorithms…”
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Mettl14-mediated m6A modification is essential for visual function and retinal photoreceptor survival by Yang, Yeming, Shuai, Ping, Li, Xiao, Sun, Kuanxiang, Jiang, Xiaoyan, Liu, Wenjing, Le, Weidong, Jiang, Haisong, Liu, Yuping, Zhu, Xianjun

“…As the most abundant epigenetic modification of eukaryotic mRNA, N6-methyladenosine (m6A) modification has been shown to play a role in mammalian nervous…”
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Tmem30a Plays Critical Roles in Ensuring the Survival of Hematopoietic Cells and Leukemia Cells in Mice by Li, Ning, Yang, Yeming, Liang, Cailing, Qiu, Qiang, Pan, Cong, Li, Mengyuan, Yang, Shengyong, Chen, Lijuan, Zhu, Xianjun, Hu, Yiguo

“…The fundamental structure of eukaryotic cell plasma membrane is the phospholipid bilayer, which contains four major phospholipids. These phospholipids are…”
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Loss of phosphatidylserine flippase β-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis by Liu, Wenjing, Peng, Lei, Tian, Wanli, Li, Yi, Zhang, Ping, Sun, Kuanxiang, Yang, Yeming, Li, Xiao, Li, Guisen, Zhu, Xianjun

“…The asymmetric distribution of phosphatidylserine (PS) in the cytoplasmic leaflet of eukaryotic cell plasma membranes is regulated by a group of P4-ATPases…”
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Hepatic Tmem30a Deficiency Causes Intrahepatic Cholestasis by Impairing Expression and Localization of Bile Salt Transporters by Liu, Leiming, Zhang, Lingling, Zhang, Lin, Yang, Fan, Zhu, Xudong, Lu, Zhongjie, Yang, Yeming, Lu, Haiqi, Feng, Lifeng, Wang, Zhuo, Chen, Hui, Yan, Sheng, Wang, Lin, Ju, Zhenyu, Jin, Hongchuan, Zhu, Xianjun

“…Mutations in ATP8B1 or ATP11C (members of P4-type ATPases) cause progressive familial intrahepatic cholestasis type 1 in human or intrahepatic cholestasis in…”
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A missense mutation in Pitx2 leads to early-onset glaucoma via NRF2-YAP1 axis by Yang, Yeming, Li, Xiao, Wang, Jieping, Tan, Junkai, Fitzmaurice, Bernie, Nishina, Patsy M., Sun, Kuanxiang, Tian, Wanli, Liu, Wenjing, Liu, Xuyang, Chang, Bo, Zhu, Xianjun

“…Glaucoma is a leading cause of blindness, affecting 70 million people worldwide. Owing to the similarity in anatomy and physiology between human and mouse eyes…”
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The endoplasmic reticulum membrane protein complex subunit Emc6 is essential for rhodopsin localization and photoreceptor cell survival by Sun, Kuanxiang, Liu, Lu, Jiang, Xiaoyan, Wang, Heting, Wang, Lin, Yang, Yeming, Liu, Wenjing, Zhang, Lin, Zhao, Xiaohui, Zhu, Xianjun

“…The endoplasmic reticulum (ER) membrane protein complex (EMC) is responsible for monitoring the biogenesis and synthetic quality of membrane proteins with…”
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Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells by Yang, Yeming, Sun, Kuanxiang, Liu, Wenjing, Zhang, Lin, Peng, Kun, Zhang, Shanshan, Li, Shujin, Yang, Mu, Jiang, Zhilin, Lu, Fang, Zhu, Xianjun

“…Phospholipids are asymmetrically distributed across mammalian plasma membrane with phosphatidylserine (PS) and phosphatidylethanolamine concentrated in the…”
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Loss of Tmem30a leads to photoreceptor degeneration by Zhang, Lin, Yang, Yeming, Li, Shujin, Zhang, Shanshan, Zhu, Xiong, Tai, Zhengfu, Yang, Mu, Liu, Yuqing, Guo, Xinzheng, Chen, Bo, Jiang, Zhilin, Lu, Fang, Zhu, Xianjun

“…Phosphatidylserine (PS) is asymmetrically distributed between the outer and inner leaflets of the plasma membrane in eukaryotic cells. PS asymmetry on the…”
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Defective EMC1 drives abnormal retinal angiogenesis via Wnt/β-catenin signaling and may be associated with the pathogenesis of familial exudative vitreoretinopathy by Li, Shujin, Yang, Mu, Zhao, Rulian, Peng, Li, Liu, Wenjing, Jiang, Xiaoyan, He, Yunqi, Dai, Erkuan, Zhang, Lin, Yang, Yeming, Shi, Yi, Zhao, Peiquan, Yang, Zhenglin, Zhu, Xianjun

“…Endoplasmic reticulum (ER) membrane protein complex (EMC) is required for the co-translational insertion of newly synthesized multi-transmembrane proteins…”
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CTNND1 variants cause familial exudative vitreoretinopathy through Wnt/Cadherin axis by Yang, Mu, Li, Shujin, Huang, Li, Zhao, Rulian, Dai, Erkuan, Jiang, Xiaoyan, He, Yunqi, Lu, Jinglin, Peng, Li, Liu, Wenjing, Zhang, Zhaotian, Jiang, Dan, Zhang, Yi, Jiang, Zhilin, Yang, Yeming, Zhao, Peiquan, Zhu, Xianjun, Ding, Xiaoyan, Yang, Zhenglin

“…Familial exudative vitreoretinopathy (FEVR) is a hereditary disorder that can cause vision loss. The CTNND1 gene encodes a cellular adhesion protein…”
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Deletion of Asrgl1 Leads to Photoreceptor Degeneration in Mice by Zhou, Yu, Tian, Wanli, Jiang, Xiaoyan, Yang, Huining, Jiang, Zhilin, Li, Xiao, Jiang, Dan, Sun, Kuanxiang, Yang, Yeming, Liu, Wenjing, Zhu, Xianjun

“…The asparaginase and isoaspartyl peptidase 1 (ASRGL1) is an L-asparaginase and beta-aspartyl peptidase enzyme that may be involved in the formation of…”
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Dialect competence, dialect attitude and social inclusion: A case study of migrants in Chongqing, China by Yang, Jinlong, Yang, Yeming

“…Adopting methods of the questionnaire, matched-guise test and semi-structured interview among different occupational groups of migrants in Chongqing, China,…”
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Dysregulated m6A modification promotes lipogenesis and development of non-alcoholic fatty liver disease and hepatocellular carcinoma by Yang, Yeming, Cai, Jingshu, Yang, Xue, Wang, Kaifang, Sun, Kuanxiang, Yang, Zhenglin, Zhang, Lin, Yang, Lu, Gu, Chun, Huang, Xiang, Wang, Ziyan, Zhu, Xianjun

“…Type 2 diabetes mellitus (DM2) is associated closely with non-alcoholic fatty liver disease (NAFLD) by affecting lipid metabolism, which may lead to…”
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The phosphatidylserine flippase β-subunit Tmem30a is essential for normal insulin maturation and secretion by Yang, Yeming, Sun, Kuanxiang, Liu, Wenjing, Li, Xiao, Tian, Wanli, Shuai, Ping, Zhu, Xianjun

“…The processing, maturation, and secretion of insulin are under precise regulation, and dysregulation causes profound defects in glucose handling, leading to…”
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Specific ablation of Hippo signalling component Yap1 in retinal progenitors and Müller cells results in late onset retinal degeneration by Yang, Yeming, Jiang, Xiaoyan, Li, Xiao, Sun, Kuanxiang, Zhu, Xianjun, Zhou, Bo

“…Yes‐associated protein (YAP) is a major component of the Hippo pathway involved in development, growth, repair and homeostasis. Nonsense YAP1 mutations in…”
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