Search Results - "Yang, Xiaojing Helen"

Early Process Development of PF-07054894, a Squaramide-Based Antagonist of C–C Chemokine Receptor Type 6 (CCR6) by Chinigo, Gary M., McInturff, Emma L., Bagley, Scott W., Barnhart, Richard W., Blakemore, David C., Han, Lu, Lee, Taegyo, Magano, Javier, McWilliams, J. Christopher, Monfette, Sebastien, Mousseau, James J., Pan, Senliang, Pedro, Dylan, Perfect, Hahdi H., Raggon, Jeffrey W., Rose, Peter R., Sagal, John, Trujillo, John I., Van Haitsma, Jared, Vetelino, Michael G., Yang, Xiaojing Helen

“…The original synthesis of a CCR6 antagonist and subsequent enablement for kilogram manufacture is presented. Highlighted improvements made in the preparation…”
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Tale of Two Polymorphs: Investigating the Structural Differences and Dynamic Relationship between Nirmatrelvir Solid Forms (Paxlovid) by Sadeghi, Maryam Sadat, Guo, Rui, Bellucci, Michael A., Quino, Jaypee, Buckle, Erika L., Nisbet, Matthew L., Yang, Zhuocen, Greenwell, Chandler, Gorka, Danielle E., Pickard IV, Frank C., Wood, Geoffrey P. F., Sun, Guangxu, Wen, Shu-Hao, Krzyzaniak, Joseph F., Meenan, Paul A., Hancock, Bruno C., Yang, Xiaojing Helen

“…Two anhydrous polymorphs of the novel antiviral medicine nirmatrelvir were discovered during the development of Paxlovid, Pfizer’s oral Covid-19 treatment. A…”
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