Search Results - "Yang, X Frank"

A Fur family protein BosR is a novel RNA-binding protein that controls rpoS RNA stability in the Lyme disease pathogen by Raghunandanan, Sajith, Priya, Raj, Alanazi, Fuad, Lybecker, Meghan C, Schlax, Paula Jean, Yang, X Frank

“…The σ54-σS sigma factor cascade plays a central role in regulating differential gene expression during the enzootic cycle of Borreliella burgdorferi, the Lyme…”
Get full text

Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen by Radolf, Justin D., Deka, Ranjit K., Anand, Arvind, Šmajs, David, Norgard, Michael V., Yang, X. Frank

“…Key Points Pathogenic treponemes are clonal, unculturable, highly invasive bacteria that cause venereal syphilis, yaws, endemic syphilis and pinta —…”
Get full text

Emerging tick-borne infections in mainland China: an increasing public health threat by Fang, Li-Qun, PhD, Liu, Kun, MS, Li, Xin-Lou, MS, Liang, Song, PhD, Yang, Yang, PhD, Yao, Hong-Wu, MS, Sun, Ruo-Xi, BS, Sun, Ye, BS, Chen, Wan-Jun, BS, Zuo, Shu-Qing, PhD, Ma, Mai-Juan, PhD, Li, Hao, PhD, Jiang, Jia-Fu, PhD, Liu, Wei, Prof, Yang, X Frank, Prof, Gray, Gregory C, Prof, Krause, Peter J, MD, Cao, Wu-Chun, Prof

“…Summary Since the beginning of the 1980s, 33 emerging tick-borne agents have been identified in mainland China, including eight species of spotted fever group…”
Get full text

Protective Immunity and New Vaccines for Lyme Disease by Gomes-Solecki, Maria, Arnaboldi, Paul M, Backenson, P Bryon, Benach, Jorge L, Cooper, Christopher L, Dattwyler, Raymond J, Diuk-Wasser, Maria, Fikrig, Erol, Hovius, J W, Laegreid, Will, Lundberg, Urban, Marconi, Richard T, Marques, Adriana R, Molloy, Philip, Narasimhan, Sukanya, Pal, Utpal, Pedra, Joao H F, Plotkin, Stanley, Rock, Daniel L, Rosa, Patricia, Telford, Sam R, Tsao, Jean, Yang, X Frank, Schutzer, Steven E

“…Abstract Lyme disease, caused by some Borrelia burgdorferi sensu lato, is the most common tick-borne illness in the Northern Hemisphere and the number of…”
Get full text

What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira by Fouts, Derrick E, Matthias, Michael A, Adhikarla, Haritha, Adler, Ben, Amorim-Santos, Luciane, Berg, Douglas E, Bulach, Dieter, Buschiazzo, Alejandro, Chang, Yung-Fu, Galloway, Renee L, Haake, David A, Haft, Daniel H, Hartskeerl, Rudy, Ko, Albert I, Levett, Paul N, Matsunaga, James, Mechaly, Ariel E, Monk, Jonathan M, Nascimento, Ana L T, Nelson, Karen E, Palsson, Bernhard, Peacock, Sharon J, Picardeau, Mathieu, Ricaldi, Jessica N, Thaipandungpanit, Janjira, Wunder, Jr, Elsio A, Yang, X Frank, Zhang, Jun-Jie, Vinetz, Joseph M

“…Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread, neglected and emerging zoonotic disease. While whole genome analysis of…”
Get full text

Identification of Collagenase as a Critical Virulence Factor for Invasiveness and Transmission of Pathogenic Leptospira Species by Kassegne, Kokouvi, Hu, Weilin, Ojcius, David M., Sun, Dexter, Ge, Yumei, Zhao, Jinfang, Yang, X. Frank, Li, Lanjuan, Yan, Jie

“…Background. Leptospirosis is a global zoonotic disease. Transmission of Leptospira from animals to humans occurs through contact with water contaminated with…”
Get full text

YebC regulates variable surface antigen VlsE expression and is required for host immune evasion in Borrelia burgdorferi by Zhang, Yan, Chen, Tong, Raghunandanan, Sajith, Xiang, Xuwu, Yang, Jing, Liu, Qiang, Edmondson, Diane G, Norris, Steven J, Yang, X Frank, Lou, Yongliang

“…Borrelia burgdorferi, the Lyme disease pathogen causes persistent infection by evading the host immune response. Differential expression of the surface-exposed…”
Get full text

Toll-like receptor 3 (TLR3) promotes the resolution of Chlamydia muridarum genital tract infection in congenic C57BL/6N mice by Carrasco, Sebastian E, Hu, Sishun, Imai, Denise M, Kumar, Ramesh, Sandusky, George E, Yang, X Frank, Derbigny, Wilbert A

“…Chlamydia trachomatis urogenital serovars primarily replicate in epithelial cells lining the reproductive tract. Epithelial cells recognize Chlamydia through…”
Get full text

DhhP, a cyclic di-AMP phosphodiesterase of Borrelia burgdorferi, is essential for cell growth and virulence by Ye, Meiping, Zhang, Jun-Jie, Fang, Xin, Lawlis, Gavin B, Troxell, Bryan, Zhou, Yan, Gomelsky, Mark, Lou, Yongliang, Yang, X Frank

“…Cyclic di-AMP (c-di-AMP) is a recently discovered second messenger in bacteria. Most of work on c-di-AMP signaling has been done in Gram-positive bacteria,…”
Get full text

Leptospiral hemolysins induce proinflammatory cytokines through Toll-like receptor 2-and 4-mediated JNK and NF-κB signaling pathways by Wang, Huan, Wu, Yifei, Ojcius, David M, Yang, X Frank, Zhang, Chenglin, Ding, Shibiao, Lin, Xu'ai, Yan, Jie

“…Infection with pathogenic Leptospira species causes serious systemic inflammation in patients. Although a few leptospiral proinflammatory molecules have been…”
Get full text

Manganese and Zinc Regulate Virulence Determinants in Borrelia burgdorferi by Troxell, Bryan, Ye, Meiping, Yang, Youyun, Carrasco, Sebastian E, Lou, Yongliang, Yang, X Frank

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Three-Dimensional Structures of Pathogenic and Saprophytic Leptospira Species Revealed by Cryo-Electron Tomography by Raddi, Gianmarco, Morado, Dustin R, Yan, Jie, Haake, David A, Yang, X. Frank, Liu, Jun

“…Leptospira interrogans is the primary causative agent of the most widespread zoonotic disease, leptospirosis. An in-depth structural characterization of L…”
Get full text

Transferred interbacterial antagonism genes augment eukaryotic innate immune function by Chou, Seemay, Daugherty, Matthew D., Peterson, S. Brook, Biboy, Jacob, Yang, Youyun, Jutras, Brandon L., Fritz-Laylin, Lillian K., Ferrin, Michael A., Harding, Brittany N., Jacobs-Wagner, Christine, Yang, X. Frank, Vollmer, Waldemar, Malik, Harmit S., Mougous, Joseph D.

“…Documented cases of horizontal gene transfer from bacteria to eukaryotes are rare, but now, not only is a new class of transferred genes identified, the…”
Get full text

Rrp2, a Prokaryotic Enhancer-Like Binding Protein, Is Essential for Viability of Borrelia burgdorferi by Groshong, Ashley M, Gibbons, Nora E, Yang, X. Frank, Blevins, Jon S

“…The Lyme disease spirochete, Borrelia burgdorferi, exists in two diverse niches (i.e., an arthropod tick vector and mammalian host) during its enzootic life…”
Get full text

Cyclic di-GMP is essential for the survival of the lyme disease spirochete in ticks by He, Ming, Ouyang, Zhiming, Troxell, Bryan, Xu, Haijun, Moh, Akira, Piesman, Joseph, Norgard, Michael V, Gomelsky, Mark, Yang, X Frank

“…Cyclic dimeric GMP (c-di-GMP) is a bacterial second messenger that modulates many biological processes. Although its role in bacterial pathogenesis during…”
Get full text

Insight into the Dual Functions of Bacterial Enhancer-Binding Protein Rrp2 of Borrelia burgdorferi by Yin, Yanping, Yang, Youyun, Xiang, Xuwu, Wang, Qian, Yang, Zhang-Nv, Blevins, Jon, Lou, Yongliang, Yang, X Frank

“…It is well established that the RpoN-RpoS sigma factor (σ(54)-σ(S)) cascade plays an essential role in differential gene expression during the enzootic cycle…”
Get full text

Cyclic Di-GMP Receptor PlzA Controls Virulence Gene Expression through RpoS in Borrelia burgdorferi by He, Ming, Zhang, Jun-Jie, Ye, Meiping, Lou, Yongliang, Yang, X Frank

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane by Xue, Feng, Dong, Haiyan, Wu, Jinyu, Wu, Zuowei, Hu, Weilin, Sun, Aihua, Troxell, Bryan, Yang, X Frank, Yan, Jie

“…Leptospira interrogans is the major causative agent of leptospirosis. Phagocytosis plays important roles in the innate immune responses to L. interrogans…”
Get full text

Essential Role of the Response Regulator Rrp2 in the Infectious Cycle of Borrelia burgdorferi by Boardman, Bethany K, He, Ming, Ouyang, Zhiming, Xu, Haijun, Pang, Xiujuan, Yang, X. Frank

“…Alteration of surface lipoprotein profiles is a key strategy that the Lyme disease pathogen, Borrelia burgdorferi, has evolved to be maintained within its…”
Get full text

Increased interleukin-17 in peripheral blood and cerebrospinal fluid of neurosyphilis patients by Wang, Cuini, Zhu, Lin, Gao, Zixiao, Guan, Zhifang, Lu, Haikong, Shi, Mei, Gao, Ying, Xu, Huanbin, Yang, X Frank, Zhou, Pingyu

“…Treponema pallidum infection evokes vigorous immune responses, resulting in tissue damage. Several studies have demonstrated that IL-17 may be involved in the…”
Get full text