Search Results - "Yang, Wen K."

Mesenchymal Stem Cell Targeting of Microscopic Tumors and Tumor Stroma Development Monitored by Noninvasive In vivo Positron Emission Tomography Imaging by HUNG, Shih-Chieh, DENG, Win-Ping, WEI, Hon-Jian, GELOVANI, Juri G, YANG, Wen K, LIU, Ren-Shyan, LEE, Chien-Chih, SU, Tzu-Chi, LIN, Rue-Jen, YANG, Den-Mei, CHANG, Chi-Wei, CHEN, Wei-Hong

“…The aim of this study was to assess the efficacy human mesenchymal stem cells (hMSC) for targeting microscopic tumors and suicide gene or cytokine gene…”
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Factors associated with resistance to SARS-CoV-2 infection discovered using large-scale medical record data and machine learning by Yang, Kai-Wen K, Paris, Chloé F, Gorman, Kevin T, Rattsev, Ilia, Yoo, Rebecca H, Chen, Yijia, Desman, Jacob M, Wei, Tony Y, Greenstein, Joseph L, Taylor, Casey Overby, Ray, Stuart C

“…There have been over 621 million cases of COVID-19 worldwide with over 6.5 million deaths. Despite the high secondary attack rate of COVID-19 in shared…”
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Non-invasive in vivo imaging with radiolabelled FIAU for monitoring cancer gene therapy using herpes simplex virus type 1 thymidine kinase and ganciclovir by Deng, Win-Ping, Yang, Wen K, Lai, Wen-Fu, Liu, Ren-Shyan, Hwang, Jeng-Jong, Yang, Den-Mei, Fu, Ying-Kai, Wang, Hsin-Ell

“…An experimental cancer gene therapy model was employed to develop a non-invasive imaging procedure using radiolabelled 2'-fluoro-2'-deoxy-5-iodo-1-beta-…”
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Tissue engineered cartilage using human articular chondrocytes immortalized by HPV-16 E6 and E7 genes by Chen, Wei-Hung, Lai, Wen-Fu, Deng, Win-Ping, Yang, Wen K., Lo, Wen-Cheng, Wu, Cheng-Chia, Yang, Den-Mei, Lai, Ming-Tang, Lin, Che-Tong, Lin, Tsou-Wen, Yang, Charng-Bin

“…Chondrocytes are useful as a cell culture system for studying arthritic degeneration in tissue engineered cartilage. However, primary chondrocytes have short…”
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Colon cancer cells with high invasive potential are susceptible to induction of apoptosis by a selective COX‐2 inhibitor by Chen, Wei‐Shone, Liu, Jin‐Hwang, Wei, Sung‐Jen, Liu, Jacqueline Ming, Hong, Chi‐Yuan, Yang, Wen K.

“…Cyclooxygenase‐2 (COX‐2) expression has been shown to correlate with the invasiveness of colon cancer cells. To further investigate this positive correlation…”
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PIK3CA as an oncogene in cervical cancer by MA, Y.-Y, WEI, S.-J, LIN, Y.-C, LUNG, J.-C, CHANG, T.-C, WHANG-PENG, J, LIU, J. M, YANG, D.-M, YANG, W. K, SHEN, C.-Y

“…Amplification of chromosome arm 3q is the most consistent aberration in cervical cancer, and is implicated in the progression of dysplastic uterine cervical…”
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Immortalization without neoplastic transformation of human mesenchymal stem cells by transduction with HPV16 E6/E7 genes by Hung, Shih‐Chieh, Yang, Den‐Mei, Chang, Ching‐Fang, Lin, Ruey‐Jen, Wang, Jih‐Shiuan, Low‐Tone Ho, Larry, Yang, Wen K.

“…hMSCs derived from bone marrow are useful as a species‐specific cell culture system for studying cell lineage differentiation and tissue remodeling. However,…”
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Modifying the Design Sprint Methodology: Leveraging Online Tools for Collaborating and Prototyping in Research Settings by Coffen-Burke, Juandalyn, Yang, Kai-Wen K., Taylor, Casey Overby

“…This tutorial provides an overview of a human-centered design approach called a design sprint. The main structure of the tutorial includes a review of the…”
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Patterns of healthcare utilization according to health equity determinants during the first year of the pandemic at Johns Hopkins Medicine by Yang, Kai-Wen K, Rattsev, Ilia, Lkhagvajav, Zoljargal, Flaks-Manov, Natalie, Gorman, Kevin, Epstein, Jeremy Aaron, Crainiceanu, Ciprian M, Taylor, Casey O

“…Rapid telehealth adoption happened at the onset of the coronavirus disease 2019 (COVID-19) pandemic, resulting in a move from to care delivery. Later, in…”
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Protein tyrosine phosphatase activities are involved in apoptotic cancer cell death induced by GL331, a new homolog of etoposide by Huang, Tze-Sing, Shu, Chih-Hung, Shih, Yung-Luen, Huang, Huey-Chung, Su, Yi-Chun, Chao, Yee, Yang, Wen K., Whang-Peng, Jacqueline

“…GL331 is a semisynthetic topoisomerase II inhibitor derived from a plant toxin podophyllotoxin. In 72-h exposure assays, LD 50 values of GL331 range from 0.5…”
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Designing Software for Genomics Medicine Service Leaders to Engage Stakeholders by Coffen-Burke, Juandalyn, Yang, Kai-Wen K., Lkhagvajav, Zoljargal, Lu, Yuzhi L., Segbefia, Tamisha Dzifa, Wang, Natalie, Stevenson, James Michael, Taylor, Casey Overby

“…Background: Stakeholder engagement can be challenging yet is critically important for the success of a new genomic medicine service or genetic test offering…”
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Modulation of tissue factor and thrombomodulin expression in human aortic endothelial cells incubated with high glucose by Wang, Huang-Joe, Huang, Huey-Chun, Chuang, Yi-Ching, Liao, Pei-Ju, Yang, Den-Mei, Yang, Wen K., Huang, Haimei

“…Diabetes is often associated with atherothrombosis. It is unknown whether high glucose can modulate the expression of tissue factor (TF) and thrombomodulin…”
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Study of [18 F]FLT and [123 I]IaraU for cellular imaging in HSV1 tk -transfected murine fibrosarcoma cells: evaluation of the tracer uptake using 5-fluoro, 5-iodo and 5-iodovinyl arabinosyl uridines as competitive probes by Huang, Ho-Lien, Chiang, Li-Wu, Chen, Jia-Rong, Yang, Wen K, Jeng, Kee-Ching, Chen, Jenn-Tzong, Duh, Ting-Shien, Lin, Wuu-Jyh, Farn, Shiou-Shiow, Chiang, Chi-Shiun, Huang, Chia-Wen, Lin, Kun-I, Yu, Chung-Shan

“…Abstract As one of the most intensively studied probes for imaging of the cellular proliferation, [18 F]FLT was investigated whether the targeting specificity…”
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The transcriptional activity of HERV-I LTR is negatively regulated by its cis-elements and wild type p53 tumor suppressor protein by Chang, Nien-Tzu, Yang, Wen K, Huang, Huey-Chung, Yeh, Kai-Wun, Wu, Cheng-Wen

“…Human endogenous retroviruses (HERVs), abundantly inter-dispersed in the genome, carry long terminal repeats (LTRs) that may potentially retro-transpose to new…”
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Paradoxical effect of GM‐CSF gene transfer on the tumorigenicity and immunogenicity of murine tumors by Wang, Jie, Yang, Wen K., Yang, Yili, Wei, Sung‐Jan, Yang, Den‐Mei, Whang‐Peng, Jacqueline, Chen, Yuh‐Min, Ting, Kai‐Li, Ting, Chou‐Chik

“…The effect of granulocyte/macrophage colony‐stimulating factor (GM‐CSF) gene transfer on the tumorigenicity and immunogenicity of 2 different murine tumor…”
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Serial In Vivo Imaging of the Lung Metastases Model and Gene Therapy Using HSV1-tk and Ganciclovir by Deng, Win-Ping, Wu, Cheng-Chia, Lee, Chien-Chih, Yang, Wen K, Wang, Hsin-Ell, Liu, Ren-Shyan, Wei, Hon-Jian, Gelovani, Juri G, Hwang, Jeng-Jong, Yang, Den-Mei, Fu, Ying-Kai, Wu, Cheng-Wen

“…Noninvasive imaging in lung metastatic tumor models is used infrequently because of technical limitations in detecting metastases. We have previously used…”
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Overexpression of cyclin A but not Skp 2 correlates with the tumor relapse of human hepatocellular carcinoma by YEE CHAO, SHIH, Y.-L, CHIU, J.-H, CHAU, G.-Y, LUI, W.-Y, YANG, W. K, LEE, S.-D, HUANG, T.-S

“…Cyclin A is an S- and G2-M-phase regulatory protein, and its abnormal expression has been implicated in cellular transformation. This work was undertaken to…”
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IFN-beta induces caspase-mediated apoptosis by disrupting mitochondria in human advanced stage colon cancer cell lines by Juang, Shin-Hun, Wei, Sung-Jen, Hung, Yi-Mei, Hsu, Chiung-Yueh, Yang, Den-Mei, Liu, Ko-Jiunn, Chen, Wei-Shone, Yang, Wen K

“…Various human colon cancer cell lines tested in vitro differed significantly in susceptibility to growth inhibition of recombinant human interferon-beta…”
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S- and G2-phase Cell Cycle Arrests and Apoptosis Induced by Ganciclovir in Murine Melanoma Cells Transduced with Herpes Simplex Virus Thymidine Kinase by Wei, Sung-Jen, Chao, Yee, Hung, Yi-Mei, Lin, Wen-chang, Yang, Den-Mei, Shih, Yung-Luen, Ch'ang, Lan-Yang, Whang-Peng, Jacqueline, Yang, Wen K

“…Mechanism of cell killing by transfer of Herpes simplex virus type-1 thymidine kinase (HSVtk) and subsequent ganciclovir (GCV) treatment was examined in B16F10…”
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Abstract 3124: Cytotoxic effects of tumor-specific T lymphocytes on autologous cancer initiator stem-like glioblastoma cells by Huang, Yin-Cheng, Wei, Kuo-Chen, Chang, Chen-Nen, Yang, Wen K.

“…Abstract [Purpose] In clinical trial of autologous dendritic cell/autologous tumor cell antigens (ADCTA) adjuvant immunotherapy of glioblastoma multiforme…”
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