Search Results - "Yang, Weizhu"

Constitutive TDO2 expression promotes liver cancer progression by an autocrine IL-6 signaling pathway by Wu, Zhengzhong, Yan, Leye, Lin, Junqing, Ke, Kun, Yang, Weizhu

“…Abstract Background Increased tryptophan (Trp) metabolism by indoleamine 2,3-dioxygenase (IDO)/tryptophan 2,3-dioxygenase (TDO) represents one of the most…”
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Interventional Optical Imaging-Monitored Synergistic Effect of Radio-Frequency Hyperthermia and Oncolytic Immunotherapy by Zheng, Hui, Zhang, Feng, Monsky, Wayne, Ji, Hongxiu, Yang, Weizhu, Yang, Xiaoming

“…To develop a new interventional oncology technique using indocyanine green (ICG)-based interventional optical imaging (OI) to monitor the synergistic effect of…”
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Large-deformation and high-strength amorphous porous carbon nanospheres by Yang, Weizhu, Mao, Shimin, Yang, Jia, Shang, Tao, Song, Hongguang, Mabon, James, Swiech, Wacek, Vance, John R., Yue, Zhufeng, Dillon, Shen J., Xu, Hangxun, Xu, Baoxing

“…Carbon is one of the most important materials extensively used in industry and our daily life. Crystalline carbon materials such as carbon nanotubes and…”
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Significance of neuronal cytochrome P450 activity in opioid-mediated stress-induced analgesia by Hough, Lindsay B, Nalwalk, Julia W, Yang, Weizhu, Ding, Xinxin

“…Abstract Stressful environmental changes can suppress nociceptive transmission, a phenomenon known as “stress-induced analgesia”. Depending on the stressor and…”
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Transthyretin promotes the invasion of combined hepatocellular cholangiocarcinoma by tumor-associated macrophages by Ke, Kun, Lin, Junqing, Huang, Ning, Yan, Leye, Liao, Rihua, Yang, Weizhu

“…Patients with combined hepatocellular-cholangiocarcinoma (cHCC-CCA) have limited treatment options and poor prognosis. Tumor-associated macrophages (TAMs) are…”
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Evaluation of percutaneous transcatheter embolization for pulmonary arteriovenous malformations by Wu, ZhengZhong, Lin, JunQing, Yang, WeiZhu, Jiang, Na, Huang, Ning, Clavijo, Leonardo C

“…The purpose of this study was to assess the safety and efficacy of percutaneous transcatheter embolization (TCE) for the treatment of pulmonary arteriovenous…”
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Preliminary design of centrifugal compressor using multidisciplinary optimization method by Shouyi, Sun, Zhufeng, Yue, Lei, Li, Mengchuang, Zhang, Weizhu, Yang

“…Centrifugal compressor is widely used in turbochargers in which the aerodynamic performance and strength are invariable among the important design objectives…”
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Administration of Iodine-125 Seeds Promotes Apoptosis in Cholangiocarcinoma through the PI3K/Akt Pathway by Lin, Junqing, Yan, Leye, Wang, Xiaolong, Wu, Zhengzhong, Ke, Kun, Lin, Xin, Huang, Ning, Yang, Weizhu

“…Purpose. We aimed to examine the effects of 125I seeds on the gene expression of Bcl-2, Bax, and PI3K/Akt pathway components in cholangiocarcinoma cells…”
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Generation and characterization of a novel Cyp2a(4/5)bgs-null mouse model by Wei, Yuan, Li, Lei, Zhou, Xin, Zhang, Qing-Yu, Dunbar, Anwar, Liu, Fang, Kluetzman, Kerri, Yang, Weizhu, Ding, Xinxin

“…Knockout mouse models targeting various cytochrome P450 (P450 or CYP) genes are valuable for determining P450's biologic functions, including roles in drug…”
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Lenvatinib with or without Concurrent Drug-Eluting Beads Transarterial Chemoembolization in Patients with Unresectable, Advanced Hepatocellular Carcinoma: A Real-World, Multicenter, Retrospective Study by Xia, Dongdong, Bai, Wei, Wang, Enxin, Li, Jiaping, Chen, Xiaoming, Wang, Zhexuan, Huang, Mingsheng, Huang, Ming, Sun, Junhui, Yang, Weizhu, Lin, Zhengyu, Wu, Jianbing, Li, Zixiang, Yang, Shufa, Zhu, Xu, Chen, Zaizhong, Zhang, Yanfang, Fan, Wenzhe, Mai, Qicong, Ding, Rong, Nie, Chunhui, Feng, Long, Li, Xueda, Huang, Wukui, Sun, Jun, Wang, Qiuhe, Lv, Yong, Li, Xiaomei, Luo, Bohan, Wang, Zhengyu, Yuan, Jie, Guo, Wengang, Li, Kai, Li, Bing, Li, Ruijun, Yin, Zhanxin, Xia, Jielai, Han, Guohong

“…Introduction: Lenvatinib is the first-line treatment for advanced hepatocellular carcinoma (HCC). We aimed to compare the clinical outcomes of lenvatinib plus…”
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Mechanism of chloroform-induced renal toxicity: Non-involvement of hepatic cytochrome P450-dependent metabolism by Fang, Cheng, Behr, Melissa, Xie, Fang, Lu, Shijun, Doret, Meghan, Luo, Hongxiu, Yang, Weizhu, Aldous, Kenneth, Ding, Xinxin, Gu, Jun

“…Chloroform causes hepatic and renal toxicity in a number of species. In vitro studies have indicated that chloroform can be metabolized by P450 enzymes in the…”
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In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa by Gu, Jun, Cui, Huadong, Behr, Melissa, Zhang, Li, Zhang, Qing-Yu, Yang, Weizhu, Hinson, Jack A, Ding, Xinxin

“…Acetaminophen overdose causes toxicity in liver and extrahepatic tissues. Although it is well established that cytochrome P450 enzymes play a critical role in…”
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Deletion of the NADPH-Cytochrome P450 Reductase Gene in Cardiomyocytes Does Not Protect Mice against Doxorubicin-Mediated Acute Cardiac Toxicity by Fang, Cheng, Gu, Jun, Xie, Fang, Behr, Melissa, Yang, Weizhu, Abel, E Dale, Ding, Xinxin

“…A genetic mouse model (designated cardiomyocyte- Cpr -null) with cardiomyocyte-specific deletion of the cytochrome P450 (P450) reductase ( Cpr ) gene was…”
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Brain P450 epoxygenase activity is required for the antinociceptive effects of improgan, a nonopioid analgesic by Hough, Lindsay B., Nalwalk, Julia W., Yang, Jun, Conroy, Jennie L., VanAlstine, Melissa A., Yang, Weizhu, Gargano, Joseph, Shan, Zhixing, Zhang, Shao-Zhong, Wentland, Mark P., Phillips, James G., Knapp, Brian I., Bidlack, Jean M., Zuiderveld, Obbe P., Leurs, Rob, Ding, Xinxin

“…The search for the mechanism of action of improgan (a nonopioid analgesic) led to the recent discovery of CC12, a compound that blocks improgan…”
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Transgenic mice with a hypomorphic NADPH-cytochrome P450 reductase gene: effects on development, reproduction, and microsomal cytochrome P450 by Wu, Lin, Gu, Jun, Cui, Huadong, Zhang, Qing-Yu, Behr, Melissa, Fang, Cheng, Weng, Yan, Kluetzman, Kerri, Swiatek, Pamela J, Yang, Weizhu, Kaminsky, Laurence, Ding, Xinxin

“…A mouse model with a hypomorphic NADPH-cytochrome P450 reductase (Cpr) gene (designated Cpr(low) allele) was generated and characterized in this study. The Cpr…”
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A mouse model with liver-specific deletion and global suppression of the NADPH-cytochrome P450 reductase gene: characterization and utility for in vivo studies of cyclophosphamide disposition by Gu, Jun, Chen, Chong-Sheng, Wei, Yuan, Fang, Cheng, Xie, Fang, Kannan, Kurunthachalam, Yang, Weizhu, Waxman, David J, Ding, Xinxin

“…A mouse model combining liver-specific deletion with global suppression of the NADPH-cytochrome P450 reductase gene (Cpr) has been developed and characterized…”
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Theoretical search for heterogeneously architected 2D structures by Yang, Weizhu, Liu, Qingchang, Gao, Zongzhan, Yue, Zhufeng, Xu, Baoxing

“…Architected 2D structures are of growing interest due to their unique mechanical and physical properties for applications in stretchable electronics,…”
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The Microstructure characteristic and Its influence on the stray grains of Nickel-based single crystal superalloys prepared by Laser directed energy deposition by Zeng, Yan, Guo, Jingyi, Zhang, Jiaqi, Yang, Weizhu, Li, Lei

“…The microstructure adjustment and the stray grains inhibition are important for the preparation of Nickel-based single crystal (SX) superalloys by laser…”
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Rotation mechanics of optical scatters in stretchable metasurfaces by Zhang, Haozhe, Yang, Weizhu, Xu, Baoxing

“…Stretchable metasurface comprised of an array of optical hard-material scatters on the surface of a soft substrate is emerging as an artificially designed…”
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Vibration fatigue behavior and failure mechanism of Ni-based single-crystal film cooling hole structure under high temperature by Zhao, Yujie, Qu, Yixin, Yang, Weizhu, Wu, Jiawei, Li, Lei

“…•Stress concentration and oxidation effect lead to crack initiation of FCH specimen.•Crack propagation path of FCH specimen depends on stress gradient…”
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