Search Results - "Yang, Tie"

PopLDdecay: a fast and effective tool for linkage disequilibrium decay analysis based on variant call format files by Zhang, Chi, Dong, Shan-Shan, Xu, Jun-Yang, He, Wei-Ming, Yang, Tie-Lin

“…Abstract Motivation Linkage disequilibrium (LD) decay is of great interest in population genetic studies. However, no tool is available now to do LD decay…”
Get full text

LDBlockShow: a fast and convenient tool for visualizing linkage disequilibrium and haplotype blocks based on variant call format files by Dong, Shan-Shan, He, Wei-Ming, Ji, Jing-Jing, Zhang, Chi, Guo, Yan, Yang, Tie-Lin

“…Abstract The triangular correlation heatmap aiming to visualize the linkage disequilibrium (LD) pattern and haplotype block structure of SNPs is ubiquitous…”
Get full text

A road map for understanding molecular and genetic determinants of osteoporosis by Yang, Tie-Lin, Shen, Hui, Liu, Anqi, Dong, Shan-Shan, Zhang, Lei, Deng, Fei-Yan, Zhao, Qi, Deng, Hong-Wen

“…Osteoporosis is a highly prevalent disorder characterized by low bone mineral density and an increased risk of fracture, termed osteoporotic fracture. Notably,…”
Get full text

Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders by Guo, Jing, Yu, Ke, Dong, Shan-Shan, Yao, Shi, Rong, Yu, Wu, Hao, Zhang, Kun, Jiang, Feng, Chen, Yi-Xiao, Guo, Yan, Yang, Tie-Lin

“…Observational studies have reported the correlations between brain imaging-derived phenotypes (IDPs) and psychiatric disorders; however, whether the…”
Get full text

Assessment of bidirectional relationships between brain imaging-derived phenotypes and stroke: a Mendelian randomization study by Yu, Ke, Chen, Xiao-Feng, Guo, Jing, Wang, Sen, Huang, Xiao-Ting, Guo, Yan, Dong, Shan-Shan, Yang, Tie-Lin

“…Stroke is a major cause of mortality and long-term disability worldwide. Whether the associations between brain imaging-derived phenotypes (IDPs) and stroke…”
Get full text

RTN4B‐mediated suppression of Sirtuin 2 activity ameliorates β‐amyloid pathology and cognitive impairment in Alzheimer's disease mouse model by Wang, Yan, Yang, Jing‐Qi, Hong, Ting-Ting, Sun, Yuan‐Hong, Huang, Hai‐Li, Chen, Feng, Chen, Xiong‐Jin, Chen, Hui‐Yi, Dong, Shan‐Shan, Cui, Li‐Li, Yang, Tie‐Lin

“…Sirtuin 2 (SIRT2) is an NAD+ dependent deacetylase that is the most abundant sirtuin protein in the brain. Accumulating evidence revealed the role of SIRT2 in…”
Get full text

Scutellarin inhibits oleic acid induced vascular smooth muscle foam cell formation via activating autophagy and inhibiting NLRP3 inflammasome activation by Gao, Wen‐Cong, Yang, Tie‐Hua, Wang, Bin‐Bao, Liu, Qian, Li, Qing, Zhou, Xiao‐Huan, Zheng, Chang‐Bo, Chen, Peng

“…Abnormalities in vascular smooth muscle cells (VSMCs) are pivotal in the pathogenesis of cardiovascular pathologies such as atherosclerosis and hypertension…”
Get full text

Multiple Functional Variants at 13q14 Risk Locus for Osteoporosis Regulate RANKL Expression Through Long‐Range Super‐Enhancer by Zhu, Dong‐Li, Chen, Xiao‐Feng, Hu, Wei‐Xin, Dong, Shan‐Shan, Lu, Bing‐Jie, Rong, Yu, Chen, Yi‐Xiao, Chen, Hao, Thynn, Hlaing Nwe, Wang, Nai‐Ning, Guo, Yan, Yang, Tie‐Lin

“…ABSTRACT RANKL is a key regulator involved in bone metabolism, and a drug target for osteoporosis. The clinical diagnosis and assessment of osteoporosis are…”
Get full text

Super-regular breathers for an inhomogenous optical fiber system by Yang, Tie-Mei

“…It is critical to excite pulse wave with higher amplitudes and higher frequencies in optical application. In this work, under investigation is an inhomogeneous…”
Get full text

A Nano Drug Delivery System Based on Angelica sinensis Polysaccharide for Combination of Chemotherapy and Immunotherapy by Wang, Min-Zhe, He, Xin, Yu, Zhe, Wu, Hong, Yang, Tie-Hong

“…Combination of chemotherapy and immunotherapy has been a promising strategy in cancer treatment. Polysaccharides from (AP), a well-known Chinese herbal…”
Get full text

An Osteoporosis Risk SNP at 1p36.12 Acts as an Allele-Specific Enhancer to Modulate LINC00339 Expression via Long-Range Loop Formation by Chen, Xiao-Feng, Zhu, Dong-Li, Yang, Man, Hu, Wei-Xin, Duan, Yuan-Yuan, Lu, Bing-Jie, Rong, Yu, Dong, Shan-Shan, Hao, Ruo-Han, Chen, Jia-Bin, Chen, Yi-Xiao, Yao, Shi, Thynn, Hlaing Nwe, Guo, Yan, Yang, Tie-Lin

“…Genome-wide association studies (GWASs) have reproducibly associated variants within intergenic regions of 1p36.12 locus with osteoporosis, but the functional…”
Get full text

Multi‐tissue transcriptome‐wide association study reveals susceptibility genes and drug targets for insulin resistance‐relevant phenotypes by Duan, Yuan‐Yuan, Ke, Xin, Wu, Hao, Yao, Shi, Shi, Wei, Han, Ji‐Zhou, Zhu, Ren‐Jie, Wang, Jia‐Hao, Jia, Ying‐Ying, Yang, Tie‐Lin, Li, Meng, Guo, Yan

“…Aim Genome‐wide association studies (GWAS) have identified multiple susceptibility loci associated with insulin resistance (IR)‐relevant phenotypes. However,…”
Get full text

Bidirectional two-sample Mendelian randomization analysis identifies causal associations between relative carbohydrate intake and depression by Yao, Shi, Zhang, Meng, Dong, Shan-Shan, Wang, Jia-Hao, Zhang, Kun, Guo, Jing, Guo, Yan, Yang, Tie-Lin

“…Growing evidence suggests that relative carbohydrate intake affects depression; however, the association between carbohydrates and depression remains…”
Get full text

An Osteoporosis Susceptibility Allele at 11p15 Regulates SOX6 Expression by Modulating TCF4 Chromatin Binding by Zhu, Dong‐Li, Chen, Xiao‐Feng, Zhou, Xiao‐Rong, Hu, Shou‐Ye, Tuo, Xiao‐Mei, Hao, Ruo‐Han, Dong, Shan‐Shan, Jiang, Feng, Rong, Yu, Yang, Tie‐Lin, Yang, Zhi, Guo, Yan

“…ABSTRACT Osteoporosis is an age‐related complex disease clinically diagnosed with bone mineral density (BMD). Although several genomewide association studies…”
Get full text

Skin lesion image segmentation by using backchannel filling CNN and level sets by Huang, Lin, Zhao, Yi-Gong, Yang, Tie-Jun

“…Pigmented skin lesion image segmentation is a key step in the computer-aided diagnosis of melanoma. This image segmentation task is also difficult due to…”
Get full text

Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization study by Dong, Shan-Shan, Zhang, Kun, Guo, Yan, Ding, Jing-Miao, Rong, Yu, Feng, Jun-Cheng, Yao, Shi, Hao, Ruo-Han, Jiang, Feng, Chen, Jia-Bin, Wu, Hao, Chen, Xiao-Feng, Yang, Tie-Lin

“…Childhood obesity is reported to be associated with the risk of many diseases in adulthood. However, observational studies cannot fully account for confounding…”
Get full text

Piezoresistor defect classification using convolutional neural networks based on incremental branch growth by Huang, Lin, Zhao, Yi-Gong, Yang, Tie-Jun

“…Surface defects significantly deteriorate piezoresistor quality. We propose an accurate end-to-end classification method for piezoresistor surface defects…”
Get full text

Efficient FRET process between CsPbBr3 quantum dots and RhB dye molecules by pressure regulation by Gao, Yong-sheng, Xu, Yan-lin, Yang, Tie-shan, Wang, Hong-gang, Mu, Hai-feng, Tan, Xiao-ming, Yang, Chuan-lu, Wang, Kai, Li, Zhi-gang, Xu, Qin-feng

“…Fluorescence resonance energy transfer (FRET) based on quantum dots (QDs) and dye molecules have great application potential in biochemical fields. How to…”
Get full text

The engineering of defect-modified boron nitride ribbons: an effective adsorbent to rapid capture for tetracycline by Chen, Xi, Tang, Yufei, Xie, Zhangwen, Zheng, Wanxing, Lin, Xiuying, Tie, Yang, Liang, Qian, Zhang, Zhuangzhuang, Liu, Zhaowei, Zhao, Kang

“…Antibiotics, the persistent organic pollutants, have brought serious pollution to the aquatic environment. Therefore, it is necessary to select rapid…”
Get full text

Associations of corin genetic polymorphisms with salt sensitivity, blood pressure changes, and hypertension incidence in Chinese adults by Zou, Ting, Yao, Shi, Du, Ming‐Fei, Mu, Jian‐Jun, Chu, Chao, Hu, Gui‐Lin, Liao, Yue‐Yuan, Chen, Chen, Wang, Dan, Ma, Qiong, Yan, Yu, Jia, Hao, Wang, Ke‐Ke, Sun, Yue, Niu, Ze‐Jiaxin, Zhang, Xi, Yan, Rui‐Chen, Man, Zi‐Yue, Ren, Dan‐Feng, Wang, Lan, Gao, Wei‐Hua, Li, Hao, Wu, Yong‐Xing, Li, Chun‐Hua, Gao, Ke, Zhang, Jie, Yang, Tie‐Lin, Wang, Yang

“…Corin, a transmembrane serine protease that can cleave pro‐atrial natriuretic peptide (Pro‐ANP) into smaller bioactive molecule atrial natriuretic peptide, has…”
Get full text