Search Results - "Yang, Sungchil"
-
1
Homeostatic plasticity drives tinnitus perception in an animal model
Published in Proceedings of the National Academy of Sciences - PNAS (06-09-2011)“…Hearing loss often results in tinnitus and auditory cortical map changes, leading to the prevailing view that the phantom perception is associated with…”
Get full text
Journal Article -
2
Transient Potassium Channels: Therapeutic Targets for Brain Disorders
Published in Frontiers in cellular neuroscience (13-06-2019)“…Transient potassium current channels (I channels), which are expressed in most brain areas, have a central role in modulating feedforward and feedback…”
Get full text
Journal Article -
3
Neuroinflammation mediates noise-induced synaptic imbalance and tinnitus in rodent models
Published in PLoS biology (18-06-2019)“…Hearing loss is a major risk factor for tinnitus, hyperacusis, and central auditory processing disorder. Although recent studies indicate that hearing loss…”
Get full text
Journal Article -
4
Short-term postsynaptic plasticity facilitates predictive tracking in continuous attractors
Published in Frontiers in computational neuroscience (02-11-2023)“…Introduction The N-methyl-D-aspartate receptor (NMDAR) plays a critical role in synaptic transmission and is associated with various neurological and…”
Get full text
Journal Article -
5
Increasing endogenous activity of NMDARs on GABAergic neurons increases inhibition, alters sensory processing and prevents noise-induced tinnitus
Published in Scientific reports (20-07-2020)“…Selective enhancement of GABAergic inhibition is thought to impact many vital brain functions and interferes with the genesis and/or progression of numerous…”
Get full text
Journal Article -
6
Graphene-electrode array for brain map remodeling of the cortical surface
Published in NPG Asia materials (01-10-2021)“…Cortical maps, which are indicative of cognitive status, are shaped by the organism’s experience. Previous mapping tools, such as penetrating electrodes and…”
Get full text
Journal Article -
7
Hybrid graphene electrode for the diagnosis and treatment of epilepsy in free-moving animal models
Published in NPG Asia materials (17-02-2023)“…Various electrophysiological and imaging techniques have been studied for the diagnosis and treatment of epilepsy. In particular, electrocorticography (ECoG)…”
Get full text
Journal Article -
8
Interlamellar CA1 network in the hippocampus
Published in Proceedings of the National Academy of Sciences - PNAS (02-09-2014)“…To understand the cellular basis of learning and memory, the neurophysiology of the hippocampus has been largely examined in thin transverse slice…”
Get full text
Journal Article -
9
Distinct Firing Activities of the Hypothalamic Arcuate Nucleus Neurons to Appetite Hormones
Published in International journal of molecular sciences (26-02-2022)“…The hypothalamic arcuate nucleus (Arc) is a central unit that controls the appetite through the integration of metabolic, hormonal, and neuronal afferent…”
Get full text
Journal Article -
10
Electrophysiological measurements of synaptic connectivity and plasticity in the longitudinal dentate gyrus network from mouse hippocampal slices
Published in STAR protocols (17-03-2023)“…Longitudinal synaptic connections between dentate gyrus (DG) granule neurons in the hippocampus have been found to be correlated with increased anxiety. Here,…”
Get full text
Journal Article -
11
Distinct kinetics of inhibitory currents in thalamocortical neurons that arise from dendritic or axonal origin
Published in PloS one (18-12-2017)“…Thalamocortical neurons in the dorsal lateral geniculate nucleus (dLGN) transfer visual information from retina to primary visual cortex. This information is…”
Get full text
Journal Article -
12
Failed stabilization for long-term potentiation in the auditory cortex of FMR1 knockout mice
Published in PloS one (12-08-2014)“…Fragile X syndrome is a developmental disorder that affects sensory systems. A null mutation of the Fragile X Mental Retardation protein 1 (Fmr1) gene in mice…”
Get full text
Journal Article -
13
Therapeutic effects of phlorotannins in the treatment of neurodegenerative disorders
Published in Frontiers in molecular neuroscience (18-05-2023)“…Phlorotannins are natural polyphenolic compounds produced by brown marine algae and are currently found in nutritional supplements. Although they are known to…”
Get full text
Journal Article -
14
β-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment
Published in Cell reports (Cambridge) (09-08-2016)“…G-protein-coupled receptors (GPCRs) initiate a variety of signaling cascades, depending on effector coupling. β-arrestins, which were initially characterized…”
Get full text
Journal Article -
15
Hypothalamic TTF-1 orchestrates the sensitivity of leptin
Published in Molecular metabolism (Germany) (01-12-2022)“…Thyroid transcription factor-1 (TTF-1), a homeodomain-containing transcription factor, is predominantly expressed in discrete areas of the hypothalamus, which…”
Get full text
Journal Article -
16
Altered synaptic plasticity of the longitudinal dentate gyrus network in noise-induced anxiety
Published in iScience (17-06-2022)“…Anxiety is characteristic comorbidity of noise-induced hearing loss (NIHL), which causes physiological changes within the dentate gyrus (DG), a subfield of the…”
Get full text
Journal Article -
17
A Postsynaptic Role for Short-Term Neuronal Facilitation in Dendritic Spines
Published in Frontiers in cellular neuroscience (30-09-2016)“…Synaptic plasticity is a fundamental component of information processing in the brain. Presynaptic facilitation in response to repetitive stimuli, often…”
Get full text
Journal Article -
18
Dynamics of longitudinal dentate gyrus axons associated with seizure
Published in The Journal of physiology (01-04-2021)“…Key points Axon collaterals of DG granule neurons project towards neighbouring DG granule cell layer Longitudinal axons in the DG‐DG circuit possess denser…”
Get full text
Journal Article -
19
Tinnitus Correlates with Downregulation of Cortical Glutamate Decarboxylase 65 Expression But Not Auditory Cortical Map Reorganization
Published in The Journal of neuroscience (11-12-2019)“…Hearing loss is the biggest risk factor for tinnitus, and hearing-loss-related pathological changes in the auditory pathway have been hypothesized as the…”
Get full text
Journal Article -
20
Cortical surface plasticity promotes map remodeling and alleviates tinnitus in adult mice
Published in Progress in neurobiology (01-12-2023)“…Tinnitus induced by hearing loss is caused primarily by irreversible damage to the peripheral auditory system, which results in abnormal neural responses and…”
Get full text
Journal Article