Search Results - "Yang, Sujuan"

Role of TNF-TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications by Yang, Sujuan, Wang, Julie, Brand, David Douglass, Zheng, Song Guo

“…Tumor necrosis factor α (TNFα) is a pleiotropic cytokine which signals through TNF receptor 1 (TNFR1) and TNF receptor 2 (TNFR2). Emerging evidence has…”
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Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer by Kamerkar, Sushrut, LeBleu, Valerie S., Sugimoto, Hikaru, Yang, Sujuan, Ruivo, Carolina F., Melo, Sonia A., Lee, J. Jack, Kalluri, Raghu

“…The mutant form of the GTPase KRAS is a key driver of pancreatic cancer but remains a challenging therapeutic target. Exosomes are extracellular vesicles…”
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Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer by Chen, Yang, Yang, Sujuan, Tavormina, Jena, Tampe, Desiree, Zeisberg, Michael, Wang, Huamin, Mahadevan, Krishnan K., Wu, Chang-Jiun, Sugimoto, Hikaru, Chang, Chia-Chi, Jenq, Robert R., McAndrews, Kathleen M., Kalluri, Raghu

“…In contrast to normal type I collagen (Col1) heterotrimer (α1/α2/α1) produced by fibroblasts, pancreatic cancer cells specifically produce unique Col1…”
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Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta by Chen, Yang, Yang, Sujuan, Lovisa, Sara, Ambrose, Catherine G., McAndrews, Kathleen M., Sugimoto, Hikaru, Kalluri, Raghu

“…Type I collagen (Col1) is the most abundant protein in mammals. Col1 contributes to 90% of the total organic component of bone matrix. However, the precise…”
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Generation and testing of clinical-grade exosomes for pancreatic cancer by Mendt, Mayela, Kamerkar, Sushrut, Sugimoto, Hikaru, McAndrews, Kathleen M, Wu, Chia-Chin, Gagea, Mihai, Yang, Sujuan, Blanko, Elena V Rodriges, Peng, Qian, Ma, Xiaoyan, Marszalek, Joseph R, Maitra, Anirban, Yee, Cassian, Rezvani, Katayoun, Shpall, Elizabeth, LeBleu, Valerie S, Kalluri, Raghu

“…Exosomes are extracellular vesicles produced by all cells with a remarkable ability to efficiently transfer genetic material, including exogenously loaded…”
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Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer by Carstens, Julienne L., Yang, Sujuan, Correa de Sampaio, Pedro, Zheng, Xiaofeng, Barua, Souptik, McAndrews, Kathleen M., Rao, Arvind, Burks, Jared K., Rhim, Andrew D., Kalluri, Raghu

“…Pancreatic ductal adenocarcinoma (PDAC) is therapeutically recalcitrant and metastatic. Partial epithelial to mesenchymal transition (EMT) is associated with…”
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Improved Cross-Label Suppression Dictionary Learning for Face Recognition by Zhou, Tian, Yang, Sujuan, Wang, Lei, Yao, Jiming, Gui, Guan

“…Cross-label suppression dictionary learning is an effective approach to preserve the label property for signal representation in face recognition. This paper…”
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4078 Identification of distinct fibroblast populations with unique roles in pancreatic cancer progression and tumor immunity by Darpolor, Josephine Kebbeh, Zheng, Xiaofeng, Yang, Sujuan, Sugimoto, Hikaru, Carstens, Julienne, de Sampiao, Pedro Correa, LeBleu, Valerie, Kalluri, Raghu

“…OBJECTIVES/GOALS: The desmoplastic reaction in PDAC involves a significant accumulation of immune cells and fibroblasts.The functional diversity of carcinoma…”
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Oligomerization of Cry9Aa in solution without receptor binding, is not related with insecticidal activity by Fang, Longfa, Wang, Bo, Zhou, Zishan, Yang, Sujuan, Shu, Changlong, Song, Fuping, Bravo, Alejandra, Soberón, Mario, Zhang, Jie

“…Background: Bacillus thuringiensis Cry toxins bind with different insect midgut proteins leading to toxin oligomerization, membrane insertion and pore…”
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Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer by Chen, Yang, Kim, Jiha, Yang, Sujuan, Wang, Huamin, Wu, Chang-Jiun, Sugimoto, Hikaru, LeBleu, Valerie S., Kalluri, Raghu

“…Stromal desmoplastic reaction in pancreatic ductal adenocarcinoma (PDAC) involves significant accumulation of type I collagen (Col1). However, the precise…”
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Induced regulatory T cells remain suppressive capability on effector T cells and synovial fibroblasts in collagen-induced arthritis by Liu, Aiqun, Cui, Qi, Yang, Sujuan

“…Rheumatoid arthritis (RA) is a common autoimmune disorder initiated by inflammatory synovitis. Hyperproliferation of destructive synovial fibroblasts (SFs) is…”
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Serratus Anterior Fascia for Immediate Implant-Based Breast Reconstruction: A Case Series of 65 Patients With Breast Cancer by Chen, Ying, Yang, Can, Yang, Sujuan, Chen, Xia, Huang, Liying

“…After immediate implant-based breast reconstruction (IIBR) after mastectomy, implant exposure or capsular contracture can occur. This study aimed to evaluate…”
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Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis by Tang, Min, Chen, Yang, Li, Bingrui, Sugimoto, Hikaru, Yang, Sujuan, Yang, Changqing, LeBleu, Valerie S., McAndrews, Kathleen M., Kalluri, Raghu

“…Hepatic fibrosis is a wound healing response that results in excessive extracellular matrix (ECM) accumulation in response to chronic hepatic injury. Signal…”
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Wintertime cooling and a potential connection with transported aerosols in Hong Kong during recent decades by Yang, Xin, Zhao, Chuanfeng, Zhou, Lijing, Li, Zhanqing, Cribb, Maureen, Yang, Sujuan

“…As a southeast neighbor of the heavily industrialized and urbanized region of the Pearl River Delta (PRD), Hong Kong, China, has been susceptible to aerosols…”
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Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer by McAndrews, Kathleen M, Chen, Yang, Darpolor, J Kebbeh, Zheng, Xiaofeng, Yang, Sujuan, Carstens, Julienne L, Li, Bingrui, Wang, Huamin, Miyake, Toru, Correa de Sampaio, Pedro, Kirtley, Michelle L, Natale, Mariangela, Wu, Chia-Chin, Sugimoto, Hikaru, LeBleu, Valerie S, Kalluri, Raghu

“…The tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC) involves a significant accumulation of fibroblasts as part of the host response to…”
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Differential roles of TNFα-TNFR1 and TNFα-TNFR2 in the differentiation and function of CD4+Foxp3+ induced Treg cells in vitro and in vivo periphery in autoimmune diseases by Yang, Sujuan, Xie, Chichu, Chen, Ye, Wang, Julie, Chen, Xiaoqing, Lu, Zhengqi, June, Rayford R., Zheng, Song Guo

“…Tumor Necrosis Factor (TNF) α is a multifunctional cytokine with pro-inflammatory and anti-inflammatory characteristics. Increasing evidence suggests that…”
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Ambient air pollution exposed during preantral-antral follicle transition stage was sensitive to associate with clinical pregnancy for women receiving IVF by Li, Lipeng, Zhou, Lixiao, Feng, Tengfei, Hao, Guimin, Yang, Sujuan, Wang, Ning, Yan, Lina, Pang, Yaxian, Niu, Yujie, Zhang, Rong

“…Maternal exposure to air pollution is associated with poor reproductive outcomes in in vitro fertilization (IVF). However, the susceptible time windows are…”
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Sperm mtDNA copy number, telomere length, and seminal spermatogenic cells in relation to ambient air pollution: Results of a cross-sectional study in Jing-Jin-Ji region of China by Zhou, Lixiao, Li, Lipeng, Hao, Guimin, Li, Binghua, Yang, Sujuan, Wang, Ning, Liang, Jiaming, Sun, Hongyue, Ma, Shitao, Yan, Lina, Zhao, Chunfang, Wei, Yanjing, Niu, Yujie, Zhang, Rong

“…Evidences on the association of air pollutants and semen quality were limited and mechanism-based biomarkers were sparse. We enrolled 423 men at a fertility…”
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TGF-β: Its role in the differentiation and function of T regulatory and effector cells by YANG, Sujuan, ZHENG, Songguo

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Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer by Yang, Sujuan, Che, Sara P. Y., Kurywchak, Paul, Tavormina, Jena L., Gansmo, Liv B., Correa de Sampaio, Pedro, Tachezy, Michael, Bockhorn, Maximilian, Gebauer, Florian, Haltom, Amanda R., Melo, Sonia A., LeBleu, Valerie S., Kalluri, Raghu

“…Pancreatic cancer presents with a dismal mortality rate and is in urgent need of methods for early detection with potential for timely intervention. All living…”
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