Search Results - "Yang, Shuaixi"
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Effect of exosomal miRNA on cancer biology and clinical applications
Published in Molecular cancer (11-10-2018)“…Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely present in various body fluids. Recently, microRNAs (miRNAs) have been…”
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2
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation
Published in Cancer cell (08-03-2021)“…Lung metastasis is the major cause of breast cancer-related mortality. The neutrophil-associated inflammatory microenvironment aids tumor cells in metastatic…”
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Spatiotemporal Immune Landscape of Colorectal Cancer Liver Metastasis at Single-Cell Level
Published in Cancer discovery (01-01-2022)“…Liver metastasis, the leading cause of colorectal cancer mortality, exhibits a highly heterogeneous and suppressive immune microenvironment. Here, we sequenced…”
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4
Emerging role of exosome-derived long non-coding RNAs in tumor microenvironment
Published in Molecular cancer (20-04-2018)“…Exosomes are extracellular vesicles released by many cell types and have been attributed for their roles in many diseases including cancer. Exosomes secreted…”
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Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma
Published in Nature communications (28-03-2022)“…Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. Here, by…”
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Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression
Published in Cell discovery (08-12-2020)“…Diverse immune cells in the tumor microenvironment form a complex ecosystem, but our knowledge of their heterogeneity and dynamics within hepatocellular…”
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Advances in Engineered Macrophages: A New Frontier in Cancer Immunotherapy
Published in Cell death & disease (01-04-2024)“…Macrophages, as pivotal cells within the tumour microenvironment, significantly influence the impact of and reactions to treatments for solid tumours. The…”
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Neutrophils in the premetastatic niche: key functions and therapeutic directions
Published in Molecular cancer (14-09-2024)“…Metastasis has been one of the primary reasons for the high mortality rates associated with tumours in recent years, rendering the treatment of current…”
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Publisher Correction: Single-cell transcriptomic analysis suggests two molecularly distinct subtypes of intrahepatic cholangiocarcinoma
Published in Nature communications (17-05-2022)Get full text
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Advances in targeting cancer-associated fibroblasts through single-cell spatial transcriptomic sequencing
Published in Biomarker research (29-07-2024)“…Cancer-associated fibroblasts (CAFs) are the major components of the tumor microenvironment and are related to tumor proliferation, metastasis, relapse, and…”
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11
Single-cell transcriptomic analysis suggests two molecularly distinct subtypes of intrahepatic cholangiocarcinoma
Published in Nature communications (28-03-2022)“…Intrahepatic cholangiocarcinoma (iCCA) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment. Here, by…”
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12
Targeting neutrophils: Mechanism and advances in cancer therapy
Published in Clinical and translational medicine (01-03-2024)“…Background Cancer is a thorny problem which cannot be conquered by mankind at present and recent researchers have put their focus on tumor microenviroment…”
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The Biological Effect and Clinical Application of Long Noncoding RNAs in Colorectal Cancer
Published in Cellular physiology and biochemistry (01-01-2018)“…Colorectal cancer (CRC) is one of the most common malignancies in the world. Easier recurrence and metastasis is the main cause of mortality in CRC patients,…”
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Pre-metastatic niche: formation, characteristics and therapeutic implication
Published in Signal transduction and targeted therapy (25-09-2024)“…Distant metastasis is a primary cause of mortality and contributes to poor surgical outcomes in cancer patients. Before the development of organ-specific…”
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Regulatory mechanisms and clinical perspectives of circRNA in digestive system neoplasms
Published in Journal of Cancer (01-01-2019)“…A new star, circular RNA (circRNA), is a class of noncoding RNA with a stable cyclic structure. Exonic circRNA mainly exists in the eukaryotic cytoplasm…”
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RETRACTED ARTICLE: YAP1-induced MALAT1 promotes epithelial–mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer
Published in Oncogene (04-04-2019)“…Yes-associated protein 1 (YAP1) exerts significant effects in various malignancies. However, the oncogenic role of YAP1 remains controversial, and the…”
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Pre-operative to post-operative serum carcinoembryonic antigen ratio is a prognostic indicator in colorectal cancer
Published in Oncotarget (15-08-2017)“…We explored the prognostic significance of the pre-operative-to-post-operative serum carcinoembryonic antigen (pre-post-CEA) ratio in colorectal cancer (CRC)…”
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YAP1-induced MALAT1 promotes epithelial-mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer
Published in Oncogene (01-04-2019)“…Yes-associated protein 1 (YAP1) exerts significant effects in various malignancies. However, the oncogenic role of YAP1 remains controversial, and the…”
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N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization
Published in Theranostics (01-01-2021)“…Tumor metastasis is the leading cause of death in patients with colorectal cancer (CRC). Circular RNAs (circRNAs) have been shown to be involved in cancer…”
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Abstract PO-055: Global immune characterization of hepatocellular carcinoma identifies macrophage and T cell subsets related to disease progression
Published in Cancer research (Chicago, Ill.) (01-11-2020)“…Abstract Diverse immune cells in the tumor microenvironment form a complex ecosystem, but our knowledge of their heterogeneity and dynamics within…”
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