Search Results - "Yang, Shengqian"
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The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro
Published in Biochemical pharmacology (01-01-2021)“…[Display omitted] Baicalein is the main active compound of Scutellaria baicalensis Georgi, a medicinal herb with multiple pharmacological activities, including…”
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Static Control-Flow Analysis of User-Driven Callbacks in Android Applications
Published in 2015 IEEE/ACM 37th IEEE International Conference on Software Engineering (01-05-2015)“…Android software presents many challenges for static program analysis. In this work we focus on the fundamental problem of static control-flow analysis…”
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Conference Proceeding -
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Predictions of BuChE Inhibitors Using Support Vector Machine and Naive Bayesian Classification Techniques in Drug Discovery
Published in Journal of chemical information and modeling (25-11-2013)“…Butyrylcholinesterase (BuChE, EC 3.1.1.8) is an important pharmacological target for Alzheimer’s disease (AD) treatment. However, the currently available…”
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Systematic testing for resource leaks in Android applications
Published in 2013 IEEE 24th International Symposium on Software Reliability Engineering (ISSRE) (01-11-2013)“…The use of mobile devices and the complexity of their software continue to grow rapidly. This growth presents significant challenges for software correctness…”
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Conference Proceeding -
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Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice
Published in Acta pharmaceutica Sinica. B (01-03-2018)“…A mangiferin aglycon derivative J99745 has been identified as a potent xanthine oxidase (XOD) inhibitor by previous in vitro study. This study aimed to…”
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Prevention of vascular smooth muscle cell proliferation and injury-induced neointimal hyperplasia by CREB-mediated p21 induction: An insight from a plant polyphenol
Published in Biochemical pharmacology (01-03-2016)“…[Display omitted] Cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA)/cAMP response element (CRE)-binding protein (CREB) signaling cascade negatively…”
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Testing for poor responsiveness in android applications
Published in 2013 1st International Workshop on the Engineering of Mobile-Enabled Systems (MOBS) (01-05-2013)“…An important category of defects in Android applications are related to poor responsiveness. When the user interface thread performs expensive operations, the…”
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Conference Proceeding -
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BPGen: an automated breakpoint generator for debugging
Published in 2010 ACM/IEEE 32nd International Conference on Software Engineering (01-05-2010)“…During debugging processes, breakpoints are frequently used to inspect and understand runtime behaviors of programs. Although most development environments…”
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Conference Proceeding -
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Static Window Transition Graphs for Android (T)
Published in 2015 30th IEEE/ACM International Conference on Automated Software Engineering (ASE) (01-11-2015)“…This work develops a static analysis to create a model of the behavior of an Android application's GUI. We propose the window transition graph (WTG), a model…”
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Conference Proceeding -
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Phillyrin attenuates norepinephrine-induced cardiac hypertrophy and inflammatory response by suppressing p38/ERK1/2 MAPK and AKT/NF-kappaB pathways
Published in European journal of pharmacology (15-07-2022)“…Phillyrin, a well-known natural compound from the dried fruits of Forsythia suspensa (Thunb.) Vahl., has shown anti-inflammatory, antioxidant and anti-virus…”
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Salidroside attenuates myocardial remodeling in DOCA-salt-induced mice by inhibiting the endothelin 1 and PI3K/AKT/NFκB signaling pathways
Published in European journal of pharmacology (05-01-2024)“…Myocardial remodeling, which occurs in the final stage of cardiovascular diseases such as hypertension, can ultimately result in heart failure. However, the…”
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Phillyrin improves myocardial remodeling in salt-sensitive hypertensive mice by reducing endothelin1 signaling
Published in Journal of pharmacy and pharmacology (06-06-2024)“…Prolonged exposure to chronic hypertension places the heart under excessive strain, resulting in myocardial remodeling. Phillyrin, derived from the natural…”
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The natural product bergenin ameliorates lipopolysaccharide-induced acute lung injury by inhibiting NF-kappaB activition
Published in Journal of ethnopharmacology (22-03-2017)“…Bergenin, an active constituent of the plants of the genus Bergenia, was reported to have anti-inflammatory effects in the treatment of chronic bronchitis and…”
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Static window transition graphs for Android
Published in Automated software engineering (01-12-2018)“…This work develops a static analysis to create a model of the behavior of an Android application’s GUI. We propose the window transition graph (WTG), a model…”
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Anti-inflammatory effects and mechanism of the total flavonoids from Artemisia scoparia Waldst. et kit. in vitro and in vivo
Published in Biomedicine & pharmacotherapy (01-08-2018)“…[Display omitted] Artemisia scoparia Waldst. et Kit. is traditionally used for the treatment of jaundice urinary retention, itching wet sores, infectious…”
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Phillyrin Inhibits Isoproterenol-Induced Cardiac Hypertrophy Via P38 and NF-κB Pathways
Published in Natural product communications (01-01-2023)“…Cardiac hypertrophy (CH) is the main compensatory response to chronic heart stress and often progresses to a decompensation state potentially leading to heart…”
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Mir-454-3p induced WTX deficiency promotes hepatocellular carcinoma progressions through regulating TGF-β signaling pathway
Published in Journal of Cancer (01-01-2022)“…Wilms tumor gene on X chromosome (WTX) is an X-linked tumor suppressor gene in Wilms tumor; however, however, the molecular mechanism of WTX in the occurrence…”
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Therapeutic effect of methyl salicylate 2-O-β-d-lactoside on LPS-induced acute lung injury by inhibiting TAK1/NF-kappaB phosphorylation and NLRP3 expression
Published in International immunopharmacology (01-11-2016)“…Acute lung injury (ALI), characterized by pulmonary edema and inflammatory cell infiltration, is a common syndrome of acute hypoxemic respiratory failure…”
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Consensus models for CDK5 inhibitors in silico and their application to inhibitor discovery
Published in Molecular diversity (01-02-2015)“…Cyclin-dependent kinase 5 (CDK5) has emerged as a principal therapeutic target for Alzheimer’s disease. It is highly desirable to develop computational models…”
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