Search Results - "Yang, Se‐Ran"
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Laurus nobilis leaf extract controls inflammation by suppressing NLRP3 inflammasome activation
Published in Journal of cellular physiology (01-05-2019)“…Laurus nobilis Linn. (Lauraceae), commonly known as Bay, has been used as a traditional medicine in the Mediterranean and Europe to treat diverse immunological…”
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An Update on the Role of Nrf2 in Respiratory Disease: Molecular Mechanisms and Therapeutic Approaches
Published in International journal of molecular sciences (05-08-2021)“…Nuclear factor erythroid 2-related factor (Nrf2) is a transcriptional activator of the cell protection gene that binds to the antioxidant response element…”
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Biocompatibility and hemocompatibility of efficiently decellularized whole porcine kidney for tissue engineering
Published in Journal of biomedical materials research. Part A (01-07-2018)“…Whole kidney decellularization is a promising approach in regenerative medicine for engineering a functional organ. The reaction of the potential host depends…”
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Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells
Published in American journal of physiology. Lung cellular and molecular physiology (01-03-2008)“…Nuclear erythroid-related factor 2 (Nrf2), a redox-sensitive transcription factor, is involved in transcriptional regulation of many antioxidant genes,…”
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5
Acute Inhibition of the Human Kv1.5 Channel by H1 Receptor Antagonist Dimenhydrinate: Mode of Action
Published in Biological & pharmaceutical bulletin (01-10-2023)“…Dimenhydrinate, an H1 receptor antagonist, is generally used for the prevention and treatment of nausea and vomiting. However, cardiac arrhythmias have been…”
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Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells
Published in Respiratory research (24-10-2006)“…Cigarette smoke mediated oxidative stress and inflammatory events in the airway and alveolar epithelium are important processes in the pathogenesis of smoking…”
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7
CD49f Enhances Multipotency and Maintains Stemness Through the Direct Regulation of OCT4 and SOX2
Published in Stem cells (Dayton, Ohio) (01-05-2012)“…CD49f (integrin subunit α6) regulates signaling pathways in a variety of cellular activities. However, the role of CD49f in regulating the differentiation and…”
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Blockade of RAGE ameliorates elastase‐induced emphysema development and progression via RAGE‐DAMP signaling
Published in The FASEB journal (01-05-2017)“…ABSTRACT The receptor for advanced glycan end products (RAGE) has been identified as a susceptibility gene for chronic obstructive pulmonary disease (COPD) in…”
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Decellularized Liver Extracellular Matrix as Promising Tools for Transplantable Bioengineered Liver Promotes Hepatic Lineage Commitments of Induced Pluripotent Stem Cells
Published in Tissue engineering. Part A (01-03-2016)“…Liver transplantation is the last resort for liver failure patients. However, due to the shortage of donor organs, bioengineered liver generated from…”
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10
Inhibition of voltage‐dependent K+ channels by iloperidone in coronary arterial smooth muscle cells
Published in Journal of applied toxicology (01-09-2020)“…Iloperidone, a second‐generation atypical antipsychotic drug, is widely used in the treatment of schizophrenia. However, the side‐effects of iloperidone on…”
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Human pluripotent stem cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing
Published in Cell death discovery (15-03-2021)“…Detailed understanding of the pathogenesis and development of effective therapies for pulmonary fibrosis (PF) have been hampered by lack of in vitro human…”
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Porphyran Attenuates Neuronal Loss in the Hippocampal CA1 Subregion Induced by Ischemia and Reperfusion in Gerbils by Inhibiting NLRP3 Inflammasome-Mediated Neuroinflammation
Published in Marine drugs (01-04-2024)“…Porphyran, a sulfated polysaccharide found in various species of marine red algae, has been demonstrated to exhibit diverse bioactivities, including…”
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Inhibition of RAGE Attenuates Cigarette Smoke-Induced Lung Epithelial Cell Damage via RAGE-Mediated Nrf2/DAMP Signaling
Published in Frontiers in pharmacology (02-07-2018)“…The oxidative stress and cellular apoptosis by environmental factor including cigarette smoke induces alveolar airway remodeling leading to chronic obstructive…”
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Human Pluripotent Stem Cell-Derived Alveolar Organoids: Cellular Heterogeneity and Maturity
Published in Tuberculosis and respiratory diseases (01-01-2024)“…Chronic respiratory diseases such as idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, and respiratory infections injure the alveoli; the…”
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Human pluripotent stem cell-derived alveolar epithelial cells are alternatives for in vitro pulmotoxicity assessment
Published in Scientific reports (24-01-2019)“…Human pluripotent stem cell (hPSC)-derived alveolar epithelial cells (AECs) provide new opportunities for understanding lung development and the treatment of…”
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PTD-FGF2 Attenuates Elastase Induced Emphysema in Mice and Alveolar Epithelial Cell Injury
Published in Chronic obstructive pulmonary disease (31-12-2023)“…Aberrant communication in alveolar epithelium is a major feature of inflammatory response for the airway remodeling leading to chronic obstructive pulmonary…”
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Reactive Oxygen Species in Mesenchymal Stem Cell Aging: Implication to Lung Diseases
Published in Oxidative medicine and cellular longevity (01-01-2015)“…MSCs have become an emerging cell source with their immune modulation, high proliferation rate, and differentiation potential; indeed, they have been…”
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Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice
Published in American journal of physiology. Lung cellular and molecular physiology (01-06-2008)“…A variety of mouse models have been used to study the pathogenesis of pulmonary emphysema/chronic obstructive pulmonary disease. The effect of cigarette smoke…”
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Cigarette Smoke-Induced Respiratory Response: Insights into Cellular Processes and Biomarkers
Published in Antioxidants (01-06-2023)“…Cigarette smoke (CS) poses a significant risk factor for respiratory, vascular, and organ diseases owing to its high content of harmful chemicals and reactive…”
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Human pluripotent stem cell-derived macrophages and macrophage-derived exosomes: therapeutic potential in pulmonary fibrosis
Published in Stem cell research & therapy (02-09-2022)“…Pulmonary fibrosis (PF) is a fatal chronic disease characterized by accumulation of extracellular matrix and thickening of the alveolar wall, ultimately…”
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