Search Results - "Yang, Niansheng"

Pathogenesis of lupus nephritis: RIP3 dependent necroptosis and NLRP3 inflammasome activation by Guo, Chaohuan, Fu, Rong, Zhou, Mianjing, Wang, Shuang, Huang, Yuefang, Hu, Haoqiang, Zhao, Jijun, Gaskin, Felicia, Yang, Niansheng, Fu, Shu Man

“…RIP3 activation leads to activation of necroptosis and the NLRP3 inflammasome pathways. The activation of RIP3 in lupus nephritis (LN) has not been…”
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Podocyte Activation of NLRP3 Inflammasomes Contributes to the Development of Proteinuria in Lupus Nephritis by Fu, Rong, Guo, Chaohuan, Wang, Shuang, Huang, Yuefang, Jin, Ou, Hu, Haoqiang, Chen, Jingxian, Xu, Bihua, Zhou, Mianjing, Zhao, Jijun, Sung, Sun‐sang J., Wang, Hongyang, Gaskin, Felicia, Yang, Niansheng, Fu, Shu Man

“…Objective Development of proteinuria in lupus nephritis (LN) is associated with podocyte dysfunction. The NLRP3 inflammasome has been implicated in the…”
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RIP3 dependent NLRP3 inflammasome activation is implicated in acute lung injury in mice by Chen, Jingxian, Wang, Shuang, Fu, Rong, Zhou, Mianjing, Zhang, Tengyue, Pan, Wenxu, Yang, Niansheng, Huang, Yuefang

“…NLRP3 inflammasome is involved in the inflammatory responses during acute lung injury (ALI). RIP3 triggered NLRP3 inflammasome activation independent of…”
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Anti-dsDNA antibodies bind to TLR4 and activate NLRP3 inflammasome in lupus monocytes/macrophages by Zhang, Hui, Fu, Rong, Guo, Chaohuan, Huang, Yuefang, Wang, Hongyue, Wang, Shuang, Zhao, Jijun, Yang, Niansheng

“…NLRP3 inflammasome has been implicated in the pathogenesis of systemic lupus erythematosus (SLE). The activation of NLRP3 inflammasome results in the…”
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TIGIT regulates CD4 + T cell immunity against polymicrobial sepsis by Zhong, Xuexin, Xie, Haiping, Wang, Shuang, Ren, Tingting, Chen, Junlin, Huang, Yuefang, Yang, Niansheng

“…Sepsis is one of the major causes of death and increased health care burden in modern intensive care units. Immune checkpoints have been prompted to be key…”
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Activation of necroptosis pathway in podocyte contributes to the pathogenesis of focal segmental glomerular sclerosis by Hu, Haoqiang, Li, Mengyuan, Chen, Binfeng, Guo, Chaohuan, Yang, Niansheng

“…Background Focal segmental glomerulosclerosis (FSGS) is characterized by podocyte damage and severe proteinuria. The exact mechanism of podocyte damage and…”
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Blockage of P2X7 attenuates acute lung injury in mice by inhibiting NLRP3 inflammasome by Wang, Shuang, Zhao, Jijun, Wang, Hongyue, Liang, Yingjie, Yang, Niansheng, Huang, Yuefang

“…NLRP3 inflammasome is engaged in the inflammatory response during acute lung injury (ALI). Purinergic receptor P2X7 has been reported to be upstream of NLRP3…”
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TIGIT Deficiency Protects Mice From DSS-Induced Colitis by Regulating IL-17A–Producing CD4+ Tissue-Resident Memory T Cells by Chen, Binfeng, Ye, Baokui, Li, Mengyuan, Wang, Shuyi, Li, Jin, Lai, Yimei, Yang, Niansheng, Ke, Zunfu, Zhang, Hui

“…Tissue-resident memory T cells (T RM cells) have been shown to play an instrumental role in providing local immune responses for pathogen clearance in barrier…”
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CaMK4 Promotes Acute Lung Injury Through NLRP3 Inflammasome Activation in Type II Alveolar Epithelial Cell by Zhang, Tengyue, Li, Mengyuan, Zhao, Siyuan, Zhou, Mianjing, Liao, Huai, Wu, Haiyan, Mo, Xinyue, Wang, Hongxing, Guo, Chaohuan, Zhang, Hui, Yang, Niansheng, Huang, Yuefang

“…Background Type II alveolar epithelial cell (AEC II), in addition to its roles in maintaining lung homeostasis, takes an active role in inflammatory response…”
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Time of day influences immune response to an inactivated vaccine against SARS-CoV-2 by Zhang, Hui, Liu, Yihao, Liu, Dayue, Zeng, Qin, Li, Liubing, Zhou, Qian, Li, Mengyuan, Mei, Jie, Yang, Niansheng, Mo, Suilin, Liu, Qiusheng, Liu, Min, Peng, Sui, Xiao, Haipeng

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Time of day influences immune response to an inactivated vaccine against SARS-CoV-2 by Zhang, Hui, Liu, Yihao, Liu, Dayue, Zeng, Qin, Li, Liubing, Zhou, Qian, Li, Mengyuan, Mei, Jie, Yang, Niansheng, Mo, Suilin, Liu, Qiusheng, Liu, Min, Peng, Sui, Xiao, Haipeng

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CRAC Channel Controls the Differentiation of Pathogenic B Cells in Lupus Nephritis by Li, Xue, Zeng, Qin, Wang, Shuyi, Li, Mengyuan, Chen, Xionghui, Huang, Yuefang, Chen, Binfeng, Zhou, Mianjing, Lai, Yimei, Guo, Chaohuan, Zhao, Siyuan, Zhang, Hui, Yang, Niansheng

“…Store-operated Ca release-activated Ca (CRAC) channel is the main Ca influx pathway in lymphocytes and is essential for immune response. Lupus nephritis (LN)…”
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Iron controls T helper cell pathogenicity by promoting glucose metabolism in autoimmune myopathy by Lai, Yimei, Zhao, Siyuan, Chen, Binfeng, Huang, Yuefang, Guo, Chaohuan, Li, Mengyuan, Ye, Baokui, Wang, Shuyi, Zhang, Hui, Yang, Niansheng

“…Background T helper cells in patients with autoimmune disease of idiopathic inflammatory myopathies (IIM) are characterized with the proinflammatory…”
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The usage of biological DMARDs and clinical remission of rheumatoid arthritis in China: a real-world large scale study by An, Yuan, Liu, Tian, He, Dongyi, Wu, Lijun, Li, Juan, Liu, Yi, Bi, Liqi, Zhou, Bin, Lin, Changsong, He, Lan, Liu, Xiangyuan, Li, Xiaofeng, Yang, Niansheng, Zhang, Zhuoli, Song, Hui, Wei, Wei, Liu, Jing, Bi, Yu, Li, Zhanguo

“…The aims of this study are to characterize the biological disease-modifying antirheumatic drug (bDMARD) usage patterns in real-life and examine the remission…”
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A clinical practice guideline for the screening and assessment of enthesitis in patients with spondyloarthritis by Wu, Xinyu, Liu, Dong, Li, Yanfei, Xie, Ya, Tu, Liudan, Zhang, Yanli, Zhang, Xi, Fang, Linkai, Luo, Xiqing, Lin, Zhiming, Liao, Zetao, Rong, Limin, Ren, Jie, Zhou, Yuqi, Yang, Niansheng, Xu, Jian, Zhang, Hua, Xu, Baijie, Wu, Zhenbiao, Zhan, Feng, Li, Zhenbin, Xiao, Weiguo, Liu, Shengyun, Zhou, Yi, Ye, Shanhui, Lv, Qing, Zhang, Lijun, Zhao, Dongbao, He, Shanzhi, Zhao, Like, Wu, Lijun, Lin, He, Zhu, Yunxiao, Guo, Donggeng, Yang, Zehong, Liu, Budian, Yang, Kehu, Gu, Jieruo

“…Objective The aim of this review is to provide guidance on the selection of approaches to the screening and assessment of enthesitis in patients with…”
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Impacts of delta and omicron variants on inactivated SARS‐CoV‐2 vaccine‐induced T cell responses in patients with autoimmune diseases and healthy controls by Wang, Shuyi, Li, Jin, Wang, Shuang, Ye, Yujin, Li, Mengyuan, Liu, Yihao, Chen, Binfeng, Lai, Yimei, Li, Liubing, Zhuang, Lili, Peng, Sui, Yang, Niansheng, Zhang, Hui, Xiao, Haipeng

“…Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection causes coronavirus disease 2019 (COVID‐19), which is still devastating…”
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Serum procalcitonin and C-reactive protein for differentiating bacterial infection from disease activity in patients with systemic lupus erythematosus by Yu, Jinquan, Xu, Bingling, Huang, Yuefang, Zhao, Jijun, Wang, Shuang, Wang, Hongyue, Yang, Niansheng

“…Abstract Objective. To study the clinical value of procalcitonin (PCT) and C-reactive protein (CRP) in differentiating bacterial infection from disease…”
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Increased expression of toll-like receptor 2 in rat diabetic nephropathy by Li, Fanglin, Yang, Niansheng, Zhang, Lili, Tan, Hechang, Huang, Bin, Liang, Yingjie, Chen, Miaoyan, Yu, Xueqing

“…Inflammation is implicated in the pathogenesis of diabetic nephropathy (DN). This study examined the role of Toll-like receptor 2 (TLR2) in the progression of…”
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Ac-SDKP ameliorates the progression of lupus nephritis in MRL/lpr mice by Tan, Hechang, Zhao, Jijun, Wang, Shuang, Zhang, Lili, Wang, Hongyue, Huang, Bin, Liang, Yingjie, Yu, Xueqing, Yang, Niansheng

“…N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is an endogenous tetrapeptide which can inhibit the differentiation, migration and activation of macrophages…”
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Inhibition of Jak/STAT signaling ameliorates mice experimental nephrotic syndrome by Li, Rong, Yang, Niansheng, Zhang, Lili, Huang, Yuefang, Zhang, Rui, Wang, Fang, Luo, Mingqian, Liang, Yingjie, Yu, Xueqing

“…This study investigated the role of JAK/STAT, an important pathway for cytokine signal transduction, in the progression of chronic glomerular diseases. BALB/c…”
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