Search Results - "Yang, Nanyan"
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SARS-CoV-2 spike promotes inflammation and apoptosis through autophagy by ROS-suppressed PI3K/AKT/mTOR signaling
Published in Biochimica et biophysica acta. Molecular basis of disease (01-12-2021)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection-induced inflammatory responses are largely responsible for the death of novel…”
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Cholestasis-induced phenotypic transformation of neutrophils contributes to immune escape of colorectal cancer liver metastasis
Published in Journal of biomedical science (29-06-2024)“…Cholestasis is a common yet severe complication that occurs during the advancement of liver metastasis. However, how cholestasis impacts the development,…”
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Subsite‐specific metastatic organotropism and risk in gastric cancer: A population‐based cohort study of the US SEER database and a Chinese single‐institutional registry
Published in Cancer medicine (Malden, MA) (01-10-2023)“…Background Studies exploring whether metastatic organotropism and risk in gastric cancer (GC) differ by primary anatomical site are scarce. Methods This study…”
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Predicative value of IFITM2 in renal clear cell carcinoma: IFITM2 is associated with lymphatic metastasis and poor clinical outcome
Published in Biochemical and biophysical research communications (01-01-2021)“…Renal clear cell carcinoma (ccRCC), is an inflammation-related malignancy with poor therapeutic outcome. Interferon-induced transmembrane protein 2 (IFITM2),…”
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Cancer-Responsive Multifunctional Nanoplatform Based on Peptide Self-Assembly for Highly Efficient Combined Cancer Therapy by Alleviating Hypoxia and Improving the Immunosuppressive Microenvironment
Published in ACS applied materials & interfaces (01-02-2023)“…Hypoxia, as a main feature of the tumor microenvironment, has greatly limited the efficacy of photodynamic therapy (PDT), as well as its clinical application…”
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Matrix Stiffness Triggers Lipid Metabolic Cross-talk between Tumor and Stromal Cells to Mediate Bevacizumab Resistance in Colorectal Cancer Liver Metastases
Published in Cancer research (Chicago, Ill.) (01-11-2023)“…Abstract Bevacizumab is an anti-VEGF monoclonal antibody that plays an important role in the combination treatment of advanced colorectal cancer. However,…”
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Gold nanoparticles inhibit tumor growth via targeting the Warburg effect in a c-Myc-dependent way
Published in Acta biomaterialia (01-03-2023)“…Gold nanoparticles (AuNPs) are prospective tools for nano-based medicine that can directly target cellular biological processes to influence cell fate and…”
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EGFR‐rich extracellular vesicles derived from highly metastatic nasopharyngeal carcinoma cells accelerate tumour metastasis through PI3K/AKT pathway‐suppressed ROS
Published in Journal of extracellular vesicles (01-10-2020)“…Nasopharyngeal carcinoma (NPC) is the most common cancer with high metastatic potential that occurs in the epithelial cells of the nasopharynx. Distant…”
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Optimizing Human Epidermal Growth Factor for its Endurance and Specificity Via Directed Evolution: Functional Importance of Leucine at Position 8
Published in International journal of peptide research and therapeutics (01-12-2020)“…Epidermal growth factor regulates cell proliferation and migration by binding and activating the extracellular region of its receptor. Many engineered EGFs…”
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