Search Results - "Yang, Lu M"

Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner by Yang, Lu M, Cheah, Kathryn S E, Huh, Sung-Ho, Ornitz, David M

“…The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop…”
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FGF20‐FGFR1 signaling through MAPK and PI3K controls sensory progenitor differentiation in the organ of Corti by Su, Yutao, Yang, Lu M., Ornitz, David M.

“…Background Fibroblast Growth Factor 20 (FGF20)‐FGF receptor 1 (FGFR1) signaling is essential for cochlear hair cell (HC) and supporting cell (SC)…”
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Analysis of FGF20‐regulated genes in organ of Corti progenitors by translating ribosome affinity purification by Yang, Lu M., Stout, Lisa, Rauchman, Michael, Ornitz, David M.

“…Background Understanding the mechanisms that regulate hair cell (HC) differentiation in the organ of Corti (OC) is essential to designing genetic therapies for…”
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Sculpting the skull through neurosensory epithelial–mesenchymal signaling by Yang, Lu M., Ornitz, David M.

“…The vertebrate skull is a complex structure housing the brain and specialized sensory organs, including the eye, the inner ear, and the olfactory system. The…”
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FGF20-Expressing, Wnt-Responsive Olfactory Epithelial Progenitors Regulate Underlying Turbinate Growth to Optimize Surface Area by Yang, Lu M., Huh, Sung-Ho, Ornitz, David M.

“…The olfactory epithelium (OE) is a neurosensory organ required for the sense of smell. Turbinates, bony projections from the nasal cavity wall, increase the…”
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Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent by Mok, Ka-Wai, Saxena, Nivedita, Heitman, Nicholas, Grisanti, Laura, Srivastava, Devika, Muraro, Mauro J., Jacob, Tina, Sennett, Rachel, Wang, Zichen, Su, Yutao, Yang, Lu M., Ma’ayan, Avi, Ornitz, David M., Kasper, Maria, Rendl, Michael

“…Cell fate transitions are essential for specification of stem cells and their niches, but the precise timing and sequence of molecular events during embryonic…”
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Cellular and humoral immune response to SARS-CoV-2 vaccination and booster dose in immunosuppressed patients: An observational cohort study by Yang, Lu M., Costales, Cristina, Ramanathan, Muthukumar, Bulterys, Philip L., Murugesan, Kanagavel, Schroers-Martin, Joseph, Alizadeh, Ash A., Boyd, Scott D., Brown, Janice M., Nadeau, Kari C., Nadimpalli, Sruti S., Wang, Aileen X., Busque, Stephan, Pinsky, Benjamin A., Banaei, Niaz

“…•Both cellular and humoral immune responses to SARS-CoV-2 vaccination wane over time.•The rate of vaccine response decline is comparable between…”
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FGF20-expressing, Wnt-Responsive Olfactory Epithelial Progenitors Regulate Growth of Underlying Turbinates to Optimize Epithelial Surface Area by Yang, Lu M., Huh, Sung-Ho, Ornitz, David M.

“…The olfactory epithelium (OE) is a neurosensory organ required for the sense of smell. Turbinates, bony projections from the nasal cavity wall, increase the…”
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Aged gut microbiota contribute to different changes in antioxidant defense in the heart and liver after transfer to germ-free mice by Hong, Yang, Dong, Han, Zhou, Jing, Luo, Ya, Yuan, Ming-Ming, Zhan, Jia-Fei, Liu, Yang-Lu, Xia, Jie-Ying, Zhang, Lei

“…Age-associated impairment in antioxidant defense is an important cause of oxidative stress, and elderly individuals are usually associated with gut microbiota…”
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An XGBoost Machine Learning Based Model for Predicting Ki-67 Value ≥ 15% in TNM Stage Primary Breast Cancer Receiving Neoadjuvant Chemotherapy Using Clinical Data and Delta-Radiomic Features on Ultrasound Images and Overall Survival Analysis: A 5-Year Postoperative Follow-Up Study by Yang Lu MD, Fei Yang MD, Yichao Tao PhD, Pang An PhD

“…Objective: To establish a model based on clinical and delta-radiomic features within ultrasound images using XGBoost machine learning to predict…”
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Feasibility Study of Computed Tomographic Radiomics Model for the Prediction of Early and Intermediate Stage Hepatocellular Carcinoma Using BCLC Staging by Dong, Han, Yang, Lu, Shaofeng, Duan, Lili, Guo

“…Hepatocellular carcinoma (HCC) is a serious health concern because of its high morbidity and mortality. The prognosis of HCC largely depends on the disease…”
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Research Progress of Multiple Primary Malignancies Associated With Esophageal Cancer by Cui, Yu, Ren, Wenxia, Du, Xue, Yang, Lu, Tan, Bangxian

“…With the improvement in survival of patients with tumors, and continuous advancement of diagnostic technology and treatment modalities, instances of multiple…”
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Efficacy and safety of prostate-targeted local therapy in patients with newly diagnosed oligometastatic prostate cancer: a systematic review and meta-analysis by Qiu, Shi, Prof, Yang, Lu, MD, Deng, Linghui, MD, Liu, Liangren, MD, Han, Ping, MD, Wei, Qiang, Prof

“…Abstract Background The role of local therapy for the management of oligometastatic prostate cancer at diagnosis still remains poorly defined. We did a…”
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Risk of Neurological Toxicities Following the Use of Different Immune Checkpoint Inhibitor Regimens in Solid Tumors: A Systematic Review and Meta-analysis by Xu, Min, Nie, Yan, Yang, Ying, Lu, Yang-Tian, Su, Qiang

“…OBJECTIVES:The objective of this study was to assess risk of neurological toxicities following the use of different immune checkpoint inhibitor (ICI) regimens…”
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Aspirin and levofloxacin for the prevention of the occurrence of prostate cancer or transformation to castration-resistant prostate cancer: a two-part, open-label, randomised, controlled study by Yang, Lu, MD, Chen, Yongji, MD, Tang, Zhuang, MD, Xue, Wenbin, MD, Qiu, Shi, MD, Tan, Ping, MD, Wei, Qiang, Prof

“…Abstract Background The role that inflammation plays in the development of prostate cancer is unknown. We aimed to assess whether an anti-inflammatory drug or…”
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Noncontrast Perfusion Single-Photon Emission CT/CT Scanning by Lu, Yang, MD, PhD, Lorenzoni, Alice, MD, Fox, Josef J., MD, Rademaker, Jürgen, MD, Vander Els, Nicholas, MD, Grewal, Ravinder K., MD, Strauss, H. William, MD, Schöder, Heiko, MD

“…Background Standard ventilation and perfusion ( V ˙ / Q ˙ ) scintigraphy uses planar images for the diagnosis of pulmonary embolism (PE). To evaluate whether…”
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Laparoscopic Radical Hysterectomy and Pelvic Lymphadenectomy Can Be Routinely Used for Treatment of Early-stage Cervical Cancer: A Single-institute Experience With 404 Patients by Yang, Lu, MD, Cai, Jing, MD, PhD, Dong, Weihong, PhD, Shen, Yi, MD, Xiong, Zhoufang, MD, Wang, Hongbo, PhD, Min, Jie, MD, Li, Guiling, MD, Wang, Zehua, MD, PhD

“…Abstract Study Objective The aim of our study was to determine if laparoscopic radical hysterectomy (LRH) can be routinely used for the treatment of…”
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Low-Carbon Optimal Dispatch of Electric-Thermal System Considering Demand Response and Wind Power Consumption by LIU Zixu, MI Yang, LU Changkun, FU Yang, SU Xiangjing

“…To solve the problems of large thermoelectric coupling in combined heat and power, high carbon emission of thermal power units, and insufficient resource…”
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Comparison of Standard- and Low-Tube Voltage 320-Detector Row Volume CT Angiography in Detection of Intracranial Aneurysms with Digital Subtraction Angiography as Gold Standard by Sun, Gang, MD, PhD, Ding, Juan, MD, Lu, Yang, MD, PhD, Li, Min, MD, Li, Li, MD, Li, Guo-ying, MD, Zhang, Xu-ping, MD

“…Rationale and Objectives The aim of this study was to prospectively assess the effect of low–tube voltage (80 kVp) 320–detector row volume computed tomographic…”
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Congenital Atresia of Uterine Isthmus: Successful Diagnosis and End-To-End Anastomosis by Yang, Lin-dong, MD, Zhang, Cheng, MD, Yang, Lu, MD, Wu, Yuan-zhe, MD, Zhou, Qiu-ming, MD

“…Abstract Background Müllerian duct anomalies are rare and occasionally diagnosed in adolescents with primary amenorrhea, abdominal pain, and sexual…”
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