Search Results - "Yang, Liangchun"

PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation by Xie, Min, Yu, Yan, Kang, Rui, Zhu, Shan, Yang, Liangchun, Zeng, Ling, Sun, Xiaofang, Yang, Minghua, Billiar, Timothy R., Wang, Haichao, Cao, Lizhi, Jiang, Jianxin, Tang, Daolin

“…Sepsis, severe sepsis and septic shock are the main cause of mortality in non-cardiac intensive care units. Immunometabolism has been linked to sepsis;…”
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PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis by Yang, Liangchun, Xie, Min, Yang, Minghua, Yu, Yan, Zhu, Shan, Hou, Wen, Kang, Rui, Lotze, Michael T., Billiar, Timothy R., Wang, Haichao, Cao, Lizhi, Tang, Daolin

“…Increasing evidence suggests the important role of metabolic reprogramming in the regulation of the innate inflammatory response, but the underlying mechanism…”
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HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells by Chai, Wenwen, Ye, Fanghua, Zeng, Li, Li, Yanling, Yang, Liangchun

“…Sodium/iodide symporter (NIS)-mediated iodide uptake plays an important physiological role in regulating thyroid gland function, as well as in diagnosing and…”
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The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents by Yu, Yan, Xie, Yangchun, Cao, Lizhi, Yang, Liangchun, Yang, Minghua, Lotze, Michael T., Zeh, Herbert J., Kang, Rui, Tang, Daolin

“…Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Development of resistance to chemotherapeutic agents is a major hurdle in the…”
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S100A8 contributes to drug resistance by promoting autophagy in leukemia cells by Yang, Minghua, Zeng, Pei, Kang, Rui, Yu, Yan, Yang, Liangchun, Tang, Daolin, Cao, Lizhi

“…Autophagy is a double-edged sword in tumorigenesis and plays an important role in the resistance of cancer cells to chemotherapy. S100A8 is a member of the…”
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Antileukemic effect of venetoclax and hypomethylating agents via caspase-3/GSDME-mediated pyroptosis by Ye, Fanghua, Zhang, Wen, Fan, Chenying, Dong, Jiajia, Peng, Min, Deng, Wenjun, Zhang, Hui, Yang, Liangchun

“…The identifying of B-cell lymphoma 2 (Bcl-2) as a therapeutic target has led to a paradigm shift in acute myeloid leukemia (AML) treatment. Pyroptosis is a…”
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microRNA 30A promotes autophagy in response to cancer therapy by Yu, Yan, Cao, Lizhi, Yang, Liangchun, Kang, Rui, Lotze, Michael, Tang, Daolin

“…microRNAs (miRNAs) are a class of small regulatory RNAs that regulate gene expression at the post-transcriptional level. miRNAs play important roles in the…”
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Extracellular HMGB1 prevents necroptosis in acute myeloid leukemia cells by Liu, Yingting, Chen, Pan, Xu, Linyong, Ouyang, Meifei, Wang, Dan, Tang, Daolin, Yang, Liangchun, Xie, Min, Cao, Lizhi, Yang, Minghua

“…[Display omitted] •Etoposide induced necroptosis and promoted the release of HMGB1 in AML cells.•HMGB1 was involved in etoposide-induced…”
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Outcome of infants with acute lymphoblastic leukemia treated with the Chinese Children's Cancer Group Acute Lymphoblastic Leukemia 2015 study protocol by Leung, Alex Wk, Cai, Jiaoyang, Wan, Zhi, Qin, Jiefen, Fang, Yongjun, Sun, Lirong, Zhu, Jiashi, Hu, Shaoyan, Wang, Ningling, Gao, Pan, Tian, Xin, Zhu, Xiaofan, Zhou, Fen, Wu, Xuedong, Ju, Xiuli, Zhai, Xiaowen, Jiang, Hua, Hu, Qun, Liang, Changda, Yang, Liangchun, Zhang, Hui, Tang, Jingyan, Gao, Ju, Pui, Ching-Hon, Li, Chi-Kong

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A novel STAT1 loss-of-function mutation associated with Mendelian susceptibility to mycobacterial disease by Ye, Fanghua, Zhang, Wen, Dong, Jiajia, Peng, Min, Fan, Chenying, Deng, Wenjun, Zhang, Hui, Yang, Liangchun

“…Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare congenital immune deficiency characterized by susceptibility to weakly virulent…”
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Clinical characteristics, pathology features and outcomes of pediatric myeloid sarcoma: A retrospective case series by Ye, Fanghua, Zhang, Hui, Zhang, Wen, Dong, Jiajia, Deng, Wenjun, Yang, Liangchun

“…Myeloid sarcoma (MS) is a rare extramedullary mass with myeloid expression, which is easy to be missed and misdiagnosed, especially in the pediatric…”
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The Prognostic and Risk Factors for Children With High‐Risk Mature B‐Cell Non‐Hodgkin's Lymphoma: A Retrospective Multicenter Study by Wang, Xiaoming, Ding, Luping, Fang, Yongjun, Yan, Jie, Gao, Ju, Yang, Liangchun, Liu, Aiguo, Lu, Jun, Wang, Jingfu, Zhang, Aijun, Gao, Yijin, Ju, Xiuli

“…ABSTRACT Backgrounds and Aims Our previous study (CCCG‐BNHL‐2015) reported the treatment strategies and outcomes of pediatric B‐cell non‐Hodgkin's lymphoma…”
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A Risk Model Composed of Complete Blood Count, BRAF V600E and MAP2K1 Predicts Inferior Prognosis of Langerhans Cell Histiocytosis in Children by Wang, Leyuan, Yuan, Lin, Du, Xizi, Zhou, Kai, Yang, Yu, Qin, Qingwu, Yang, Liangchun, Xiang, Yang, Qu, Xiangping, Liu, Huijun, Qin, Xiaoqun, Liu, Chi

“…In children, Langerhans cell histiocytosis (LCH), which is the most prevalent histiocytic disorder, exhibits a wide variety of manifestations and outcomes…”
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Effect of rituximab on immune status in children with aggressive mature B-cell lymphoma/leukemia–a prospective study from CCCG-BNHL-2015 by Dong, Jiajia, Xu, Zhou, Guo, Xia, Ye, Fanghua, Fan, Chenying, Gao, Ju, Gao, Yijin, Yang, Liangchun

“…Limited research has been conducted on the impact of rituximab on immune function and the incidence of side effects in children undergoing combination…”
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Knockdown of WAVE1 enhances apoptosis of leukemia cells by downregulating autophagy by ZHANG, ZHAOXIA, WU, BENQING, CHAI, WENWEN, CAO, LIZHI, WANG, YANGPING, YU, YAN, YANG, LIANGCHUN

“…Chemoresistance of leukemia constitutes a great challenge for successful treatment of leukemia. Autophagy has recently attracted increasing attention for its…”
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Stratified Treatment in Pediatric Anaplastic Large Cell Lymphoma: Result of a Prospective Open-Label Multiple-Institution Study by Chen, Tingting, Zeng, Chenggong, Wang, Juan, Sun, Feifei, Huang, Junting, Zhu, Jia, Lu, Suying, Liao, Ning, Zhang, Xiaohong, Chen, Zaisheng, Yuan, Xiuli, Yang, Zhen, Guo, Haixia, Yang, Liangchun, Wen, Chuan, Zhang, Wenlin, Li, Yang, Luo, Xuequn, Wu, Zelin, Yang, Lihua, Liu, Riyang, Zheng, Mincui, He, Xiangling, Sun, Xiaofei, Zhen, Zijun

“…The risk stratification of pediatric anaplastic large cell lymphoma (ALCL) has not been standardized. In this study, new risk factors were included to…”
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A prospective multicenter study on varicella-zoster virus infection in children with acute lymphoblastic leukemia by Xiao, Peifang, Cai, Jiaoyang, Gao, Ju, Gao, Wei, Guan, Xianmin, Leung, Alex Wing Kwan, He, Yiying, Zhuang, Yong, Chu, Jinhua, Zhai, Xiaowen, Qi, Benquan, Liu, Aiguo, Yang, Liangchun, Zhu, Jiashi, Li, Zheng, Tian, Xin, Xue, Yao, Hao, Li, Wu, Xuedong, Zhou, Fen, Wang, Lingzhen, Tang, Jingyan, Shen, Shuhong, Hu, Shaoyan

“…Background and methods The study evaluated prognostic factors associated with varicella-zoster virus (VZV) infection and mortality in children with acute…”
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HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cells by Zhao, Mingyi, Xiangya Hospital, Central South University, Changsha, Hunan, China, Yang, Minghua, Xiangya Hospital, Central South University, Changsha, Hunan, China, Yang, Liangchun, Xiangya Hospital, Central South University, Changsha, Hunan, China, Yu, Yan, Xiangya Hospital, Central South University, Changsha, Hunan, China, Xie, Min, Xiangya Hospital, Central South University, Changsha, Hunan, China, Zhu, Shan, Xiangya Hospital, Central South University, Changsha, Hunan, China, Kang, Rui, Xiangya Hospital, Central South University, Changsha, Hunan, China, Tang, Daolin, Hillman Cancer Center, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA, Jiang, Zhigang, Hunan Normal University, Changsha, Hunan, China, Yuan, Wuzhou, Hunan Normal University, Changsha, Hunan, China, Wu, Xiushan, Hunan Normal University, Changsha, Hunan, China, Cao, Lizhi, Xiangya Hospital, Central South University, Changsha, Hunan, China

“…HMGB1 is associated with human cancers and is an activator of autophagy which mediates chemotherapy resistance. We here show that the mRNA levels of HMGB1 are…”
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Primary synovial sarcoma in the orbit by Liu, Ke, MD, Duan, Xuanchu, MD, PhD, Yang, Liangchun, MD, PhD, Yu, Yan, MD, PhD, Liu, Baoan, MD, PhD

“…Synovial sarcoma is a rare malignant neoplasm that accounts for approximately 6% to 9% of all soft-tissue tumors. It occurs predominately in upper and lower…”
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Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis by Yang, Liangchun, Ye, Fanghua, Liu, Jiao, Klionsky, Daniel J., Tang, Daolin, Kang, Rui

“…Acute pancreatitis (AP) is an abdominal inflammatory disease initiated by damaged pancreatic acinar cells and developed by systemic inflammation. SQSTM1…”
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