Search Results - "Yang, Joy"

A new versatile primer set targeting a short fragment of the mitochondrial COI region for metabarcoding metazoan diversity: application for characterizing coral reef fish gut contents by Leray, Matthieu, Yang, Joy Y, Meyer, Christopher P, Mills, Suzanne C, Agudelo, Natalia, Ranwez, Vincent, Boehm, Joel T, Machida, Ryuji J

“…The PCR-based analysis of homologous genes has become one of the most powerful approaches for species detection and identification, particularly with the…”
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Resolving the structure of phage–bacteria interactions in the context of natural diversity by Kauffman, Kathryn M., Chang, William K., Brown, Julia M., Hussain, Fatima A., Yang, Joy, Polz, Martin F., Kelly, Libusha

“…Microbial communities are shaped by viral predators. Yet, resolving which viruses (phages) and bacteria are interacting is a major challenge in the context of…”
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lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs by Yang, Liuqing, Lin, Chunru, Jin, Chunyu, Yang, Joy C., Tanasa, Bogdan, Li, Wenbo, Merkurjev, Daria, Ohgi, Kenneth A., Meng, Da, Zhang, Jie, Evans, Christopher P., Rosenfeld, Michael G.

“…A study of prostate cancer cells reveals a transcriptional activation role for long non-coding RNAs (PRNCR1 and PCGEM1) that bind to the androgen receptor, and…”
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Mechanisms of resistance in castration-resistant prostate cancer (CRPC) by Chandrasekar, Thenappan, Yang, Joy C, Gao, Allen C, Evans, Christopher P

“…Despite advances in prostate cancer diagnosis and management, morbidity from prostate cancer remains high. Approximately 20% of men present with advanced or…”
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Intracrine Androgens and AKR1C3 Activation Confer Resistance to Enzalutamide in Prostate Cancer by Liu, Chengfei, Lou, Wei, Zhu, Yezi, Yang, Joy C, Nadiminty, Nagalakshmi, Gaikwad, Nilesh W, Evans, Christopher P, Gao, Allen C

“…The introduction of enzalutamide and abiraterone has led to improvement in the treatment of metastatic castration-resistant prostate cancer. However, acquired…”
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Cross-sector comovements and policy impact in the COVID-19 stock market: A dynamic factor approach by Yang, Joy D. Xiuyao

“…This study investigates the remarkable comovements in U.S. equity returns during the COVID-19 pandemic. It constructs a dynamic factor model (DFM) to…”
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A phase IIb randomized, double-blind, placebo-controlled trial of ubrogepant for the acute treatment of migraine by Voss, Tiffini, Lipton, Richard B, Dodick, David W, Dupre, Nicole, Ge, Joy Yang, Bachman, Robert, Assaid, Christopher, Aurora, Sheena K, Michelson, David

“…The aim of this trial was to evaluate the efficacy and tolerability of ubrogepant (MK-1602), a calcitonin gene-related peptide receptor antagonist (CGRP-RA),…”
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Autophagy as a modulator and target in prostate cancer by Farrow, Jason M., Yang, Joy C., Evans, Christopher P.

“…Key Points Autophagy is a dynamic metabolic process that facilitates nutrient utilization and toxin removal: too little or too much autophagy can have…”
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Cross-Resistance Among Next-Generation Antiandrogen Drugs Through the AKR1C3/AR-V7 Axis in Advanced Prostate Cancer by Zhao, Jinge, Ning, Shu, Lou, Wei, Yang, Joy C, Armstrong, Cameron M, Lombard, Alan P, D'Abronzo, Leandro S, Evans, Christopher P, Gao, Allen C, Liu, Chengfei

“…The next-generation antiandrogen drugs, XTANDI (enzalutamide), ZYTIGA (abiraterone acetate), ERLEADA (apalutamide) and NUBEQA (darolutamide) extend survival…”
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Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer by Liu, Chengfei, Lou, Wei, Yang, Joy C., Liu, Liangren, Armstrong, Cameron M., Lombard, Alan P., Zhao, Ruining, Noel, Onika D. V., Tepper, Clifford G., Chen, Hong-Wu, Dall’Era, Marc, Evans, Christopher P., Gao, Allen C.

“…Protein homeostasis (proteostasis) is a potential mechanism that contributes to cancer cell survival and drug resistance. Constitutively active androgen…”
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AKR1C3 Promotes AR-V7 Protein Stabilization and Confers Resistance to AR-Targeted Therapies in Advanced Prostate Cancer by Liu, Chengfei, Yang, Joy C, Armstrong, Cameron M, Lou, Wei, Liu, Liangren, Qiu, Xiaomin, Zou, Binhao, Lombard, Alan P, D'Abronzo, Leandro S, Evans, Christopher P, Gao, Allen C

“…The mechanisms resulting in resistance to next-generation antiandrogens in castration-resistant prostate cancer are incompletely understood. Numerous studies…”
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Development of a stress response therapy targeting aggressive prostate cancer by Nguyen, Hao G, Conn, Crystal S, Kye, Yae, Xue, Lingru, Forester, Craig M, Cowan, Janet E, Hsieh, Andrew C, Cunningham, John T, Truillet, Charles, Tameire, Feven, Evans, Michael J, Evans, Christopher P, Yang, Joy C, Hann, Byron, Koumenis, Constantinos, Walter, Peter, Carroll, Peter R, Ruggero, Davide

“…Oncogenic lesions up-regulate bioenergetically demanding cellular processes, such as protein synthesis, to drive cancer cell growth and continued…”
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Distinct signaling mechanisms regulate migration in unconfined versus confined spaces by Hung, Wei-Chien, Chen, Shih-Hsun, Paul, Colin D, Stroka, Kimberly M, Lo, Ying-Chun, Yang, Joy T, Konstantopoulos, Konstantinos

“…Using a microchannel assay, we demonstrate that cells adopt distinct signaling strategies to modulate cell migration in different physical microenvironments…”
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Topographic diversity of fungal and bacterial communities in human skin by Findley, Keisha, Oh, Julia, Yang, Joy, Conlan, Sean, Deming, Clayton, Meyer, Jennifer A., Schoenfeld, Deborah, Nomicos, Effie, Park, Morgan, Kong, Heidi H., Segre, Julia A.

“…Microbial sequencing of samples obtained from multiple skin sites in healthy human adults shows that core-body and arm sites are dominated by fungal species of…”
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ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer by Wang, Junjian, Zou, June X, Xue, Xiaoqian, Cai, Demin, Zhang, Yan, Duan, Zhijian, Xiang, Qiuping, Yang, Joy C, Louie, Maggie C, Borowsky, Alexander D, Gao, Allen C, Evans, Christopher P, Lam, Kit S, Xu, Jianzhen, Kung, Hsing-Jien, Evans, Ronald M, Xu, Yong, Chen, Hong-Wu

“…ROR-γ antagonists suppress androgen receptor expression and growth of prostate tumors, but not of androgen-responsive healthy tissue, in preclinical models…”
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KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis by Wang, Ling-Yu, Hung, Chiu-Lien, Chen, Yun-Ru, Yang, Joy C., Wang, Junjian, Campbell, Mel, Izumiya, Yoshihiro, Chen, Hong-Wu, Wang, Wen-Ching, Ann, David K., Kung, Hsing-Jien

“…The histone lysine demethylase KDM4A/JMJD2A has been implicated in prostate carcinogenesis through its role in transcriptional regulation. Here, we describe…”
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Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine by Hewitt, David J, Aurora, Sheena K, Dodick, David W, Goadsby, Peter J, Ge, Yang Joy, Bachman, Robert, Taraborelli, Donna, Fan, Xiaoyin, Assaid, Christopher, Lines, Christopher, Ho, Tony W

“…This study evaluated the CGRP receptor antagonist MK-3207 for acute treatment of migraine. Multicenter, double-blind, randomized, placebo-controlled,…”
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KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC by Wang, Hung-Jung, Pochampalli, Mamata, Wang, Ling-Yu, Zou, June X, Li, Pei-Shan, Hsu, Sheng-Chieh, Wang, Bi-Juan, Huang, Shih-Han, Yang, Ping, Yang, Joy C., Chu, Cheng-Ying, Hsieh, Chia-Ling, Sung, Shian-Ying, Li, Chien-Feng, Tepper, Clifford G., Ann, David K., Gao, Allen C., Evans, Christopher P., Izumiya, Yoshihiro, Chuu, Chi-Pin, Wang, Wen-Ching, Chen, Hong-Wu, Kung, Hsing-Jien

“…During the evolution into castration or therapy resistance, prostate cancer cells reprogram the androgen responses to cope with the diminishing level of…”
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Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways by Hung, Wei-Chien, Yang, Jessica R., Yankaskas, Christopher L., Wong, Bin Sheng, Wu, Pei-Hsun, Pardo-Pastor, Carlos, Serra, Selma A., Chiang, Meng-Jung, Gu, Zhizhan, Wirtz, Denis, Valverde, Miguel A., Yang, Joy T., Zhang, Jin, Konstantopoulos, Konstantinos

“…Cells adopt distinct signaling pathways to optimize cell locomotion in different physical microenvironments. However, the underlying mechanism that enables…”
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Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer by Chen, Bo, Xu, Pengfei, Yang, Joy C., Nip, Christopher, Wang, Leyi, Shen, Yuqiu, Ning, Shu, Shang, Yufeng, Corey, Eva, Gao, Allen C., Gestwicki, Jason E., Wei, Qiang, Liu, Liangren, Liu, Chengfei

“…Treatment-induced neuroendocrine prostate cancer (t-NEPC) often arises from adenocarcinoma via lineage plasticity in response to androgen receptor signaling…”
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